35
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Targeting of an Anti-CR3 (CD11b/CD18) Monoclonal Antibody to Spleen But Not Brain, In Vivo in Mice

&
Pages 9-14 | Received 29 Jul 1994, Accepted 29 Sep 1994, Published online: 28 Sep 2008

References

  • Andersson P. B., Perry V. H., Gordon S. The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissues. Neurosci (1992); 48: 169–186
  • Cervia S. J., Rosen H., Murray H. W. Effector role of blood monocytes in experimental visceral leishmaniasis. Inf. Immun (1993); 61: 1330–1333
  • Conlan W. J., North R. J. Monoclonal antibody NIMP‐R10 directed against the CD11b chain of the type 3 complement receptor can substitute for monoclonal antibody 5C6 to exacerbate listeriosis by preventing the focusing of myelomonocytic cells at infectious foci in the liver. J Leuc. Biol (1992); 52: 130–132
  • DiRenzo L., Yefenof E., Klein E. The function of human NK cells is enhanced by b‐glucan, a ligand of CR3 (CDllb/CD18). Eur. J. Immunol (1991); 21: 1755–1758
  • Duffy K. P., Pardridge W. M. Blood‐brain barrier transcytosis of insulin in developing rabbit. Brain Res (1987); 420: 32–38
  • Friden P. M., Walus L., Musso G. F., Taylor M. A., Malfroy B., Starzyk R. M. Antitransferrin receptor antibody and antibody‐drug conjugates cross the blood‐brain barrier. Proc. Natl. Acad. Sci. USA (1991); 88: 4771–4775
  • Hutchings P., Rosen H., O'Reilly L., Simpson E., Gordon S., Cooke A. Transfer of diabetes in mice prevented by blockade of adhesion‐promoting receptor macrophages. Nature (1990); 348: 639–642
  • Jaso‐Friedmann L., Leary J. H., III, John A. L., Harris St. D. T., Koren H. S., Evans D. L. Detection of function‐associated molecules on rat NK cells and their role in target cells lysis. Cell. Immunol (1992); 141: 131–147
  • Kang Y., Bickel U., Pardridge W. M. Pharmacokinetics and saturable blood‐brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferring receptor. Drug Metabol. Disp (1994); 22: 99–105
  • Ochs H. D., Nonoyama S., Zhu Q., Farrington M., Wedgwood R. J. Regulation of antibody responses: role of complement and adhesion molecules. Clin. Immunol. Immunopathol (1993); 67: S33–S40
  • Pardridge W. M., Buciak J. L., Friden P. M. Selective transport of anti‐transferrin receptor antibody through the blood‐brain barrier in vivo. J. Pharmacol. Exp. Ther (1991); 259: 66–70
  • Reid D. M., Perry V. H., Anderson P. B., Gordon S. Mitosis and apoptosis of microglia in vivo induced by anti‐CR3 antibody which crosses the blood‐brain barrier. Neurosci (1993); 56: 529–533
  • Rosen H., Gordon S. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J. Exp. Med (1987); 166: 1685–1701
  • Rosen H., Gordon S., North R. Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. J. Exp. Med (1989); 170: 27–37
  • Ross G. D., Vetvicka V. CR3(CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions. Clin. Exp. Immunol (1993); 92: 181–184
  • Rossler K., Neuchrist C., Kitz K., Scheiner O., Kraft D., Lassmann H. Expression of leucocyte adhesion molecules at the human blood‐brain barrier (BBB). J. Neurosci. Res (1992); 31: 365–374
  • Schutze G. E., Hall M. A., Baker C. J., Edwards M. S. Role of neutrophil receptors in opsonophagocytosis of coagulasenegative staphylocci. Infect. Immun (1991); 59: 2573–2578
  • Sloan D. J., Wood M. J., Charlton H. M. Leucocyte recruitment and inflammation in the CNS. Trends Neurosci (1992); 15: 276–278
  • Tuomanen E. I., Saukkonen K., Sande S., Cioffe C., Wright S. D. Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion‐promoting receptors of leukocytes. J. Exp. Med (1989); 170: 959–968
  • Tuomanen E. I., Prasad S. M., George J. S., Hoepelman A. I.M., Ibsen P., Heron I., Starzyk R. M. Reversible opening of the blood‐brain barrier by anti‐bacterial antibodies. Proc. Nat. Acad. Sci. USA (1993); 90: 7824–7828

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.