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Research Article

Modulation of Murine Macrophage Nitric Oxide Synthesis by Liposomal Phospholipids: Correlation with Liposome Immune Adjuvant Activity

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Pages 137-147 | Received 07 Apr 1994, Accepted 29 Dec 1994, Published online: 28 Sep 2008

References

  • Abbas A. K., Urioste S., Collins T. L., Boom W. H. Heterogeneity of helper/inducer T lymphocytes. IV. Stimulation of resting and activated B cells by Thl and Th2 clones. J. Immunol. (1990); 144: 2031–2037
  • Alving C. R. Immunologic aspects of liposomes: Presentation and processing of liposomal protein and phospholipid antigens. Biochim. Biophys. Acta Rev. Biomembr. (1992); 1113: 307–322
  • Bakouche Q., David F., Gerlier D. Impairment of immunogenicity by antigen presentation in liposomes made from dimyristoylphosphatidylethanolamine linked to the secretion of prostaglandins by macrophages. Eur. J Immunol. (1987); 17: 1839–1842
  • Barratt G. M., Raddassi K., Petit J. F., Tenu J. P. MDP and LPS act synergistically to induce arginine-dependent cytostatic activity in rat alveolar macrophages. Int. J. Immunopharmacol. (1991); 13: 159–165
  • Bazzi M. D., Youakim M. A., Nelsestuen G. L. Importance of phosphatidylethanolamine for association of protein kinase C and other cytoplasmic proteins with membranes. Biochemistry (1992); 31: 1125–1134
  • Bromander A., Holmgren J., Lycke N. Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro. Cell. Immunol. (1991); 146: 2908–2914
  • Bui T., Dykers T., Hu S.-L., Faltynek C. R., Ho R. J.Y. effect of MTP-PE liposomes and interleukin-7 on induction of antibody and cell-mediated immune responses to a recombinant HIV-envelope protein. JAIDS (1994); 7: 799–806
  • Caselli E., Baricordi O. R., Melchiorri L., Bellini F., Ponzin D., Bruni A. Inhibition of DNA synthesis in peripheral blood mononuclear cells treated with phosphatidylserines containing unsaturated acyl chains. Immunopharmacology (1992); 23: 205–213
  • Caselli E., Bellini F., Ponzin D., Baricordi O. R., Bruni A. Role of protein kinase c in the phosphatidylserine-induced inhibition of DNA synthesis in blood mononuclear cells. Immunopharmacology (1992); 24: 191–201
  • Coutelier J. P., Van Der Logt J. T., Heessen F. W., Vink A., Van Snick J. Virally induced modulation of murine IgG antibody subclasses. J. Exp. Med. (1988); 168: 2373–2378
  • Cunha F. Q., Moncada S., Liew F. Y. Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-gamma in murine macrophages. Biochem. Biophys. Res. Commun. (1992); 182: 1155–1159
  • Deng W., Thiel B., Tannenbaum C. S., Hamilton T. A., Stuehr D. J. Synergistic cooperation between T cell lymphokines for induction of the nitric oxide synthase gene in murine peritoneal macrophages. J. Immunol. (1993); 151: 322–329
  • Drapier J. C., Wietzerbin J., Hibbs J. B., Jr. Interferongamma and tumor necrosis factor induce the L-argininedependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. (1988); 18: 1587–1592
  • Duits A. J., Van Puijenbroek A., Vermeulen H., Hofhuis F. M.A., Van De Winkel J. G.J., Capel P. J.A. Immunoadjuvant activity of a liposomal IL-6 formulation. Vaccine (1993); 11: 777–781
  • Fidler I. J., Sone S., Fogler W. E., Smith D., Braun D. G., Tarcsay L., Gisler R. H., Shroit A. J. Efficacy of liposomes containing a lipophilic derivative of muramyl tripeptide for activating the tumoricidal properties of alveolar macrophages in vivo. J. Biol. Resp. Modif. (1982); 1: 43–55
  • Finkelman F. D., Holmes J., Katona I. M., Urban J. F., Jr., Beckmann M. P., Park L. S., Schooley K. A., Coffman R. L., Mosmann T. R., Paul W. E. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol (1990); 8: 303–333
  • Fiorentino D. F., Bond M. W., Mosmann T. R. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. (1989); 170: 2081–2095
  • Gajewski T. F., Fitch F. W. Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J. Immunol (1988); 140: 4245–4252
  • Gajewski T. F., Pinnas M., Wong T., Fitch F. W. Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations. J. Immunol (1991); 146: 1750–1758
  • Garnier F., Forquet F., Bertolino P., Gerlier D. Enhancement of in vivo and in vitro T cell response against measles virus haemagglutinin after its incorporation into liposomes: Effect of the phospholipid composition. Vaccine (1991); 9: 340–345
  • Girolomoni G., Pastore S., Zacchi V., Cavani A., Marconi A., Giannetti A. Phosphatidylserine enhances the ability of epidermal Langerhans cells to induce contact hypersensitivity. J. Immunol (1993); 150: 4236–4243
  • Gregoriadis G., Davis D., Davies A. Liposomes as immunological adjuvants: antigen incorporation studies. Vaccine (1987); 5: 145–151
  • Harding C. V., Collins D. S., Kanagawa O., Unanue E. R. Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation. J. Immunol (1991); 147: 2860–2863
  • Ianaro A., O'Donnell C. A., Di Rosa M., Liew F. Y. A nitric oxide synthase inhibitor reduces inflammation, downregulates inflammatory cytokines and enhances interleukin-10 production in carrageenin-induced oedema in mice. Immunology (1994); 82: 370–375
  • Kelso A., Macdonald H. R., Smith K. A., Cerottini J.-C., Brunner K. T. Interleukin-2 enhancement of lymphokine secretion by T lymphocytes: analysis of established clones and primary limiting dilution microcultures. J. Immunol (1984); 132: 2932–2938
  • Kipps T. J., Parham P., Punt J., Herzenberg L. A. Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies. J. Exp. Med. (1985); 161: 1–17
  • Kleinerman E. S., Raymond A. K., Bucana C. D., Jaffe N., Harris M. B., Krakoff I. H., Benjamin R., Fidler I. J. Unique histological changes in lung metastases of osteosarcoma patients following therapy with liposomal muramyl tripeptide (CGP 19835A lipid). Cancer Immunol. Immunother. (1992); 34: 211–220
  • Kochs G., Hummel R., Fiebich B., Sarre T. F., Marme D., Hug H. Activation of purified human protein kinase c alpha and beta I isoenzymes in vitro by Ca2+, phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate. Biochem. J. (1993); 291: 627–633
  • Langrehr J. M., Hoffman R. A., Lancaster J. R., Jr., Simmons R. L. Nitric oxide-a new endogenous immunomodulator. Transplantation (1993); 55: 1205–1212
  • Liew F. Y., Li Y., Severn A., Millott S., Schmidt J., Salter M., Moncada S. A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Thl cell activity via the modulation of the induction of nitric oxide synthase on macrophages. Eur. J. Immunol (1991); 21: 2489–2494
  • Manca F., Fenoglio D., Li Pira G., Kunkl A., Celada F. Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies. J. Exp. Med. (1991); 173: 37–48
  • Manetti R., Barak V., Piccinni M.-P., Sampognaro S., Parronchi P., Maggi E., Dinarello C. A., Romagnani S. Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones. Res. Immunol (1994); 145: 93–100
  • Mannhalter J. W., Neychev H. O., Zlabinger G. J., Ahmad R., Eibl M. M. Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation. Clin. exp. Immunol (1985); 61: 143–151
  • Marcinkiewicz J., Chain B. M. Differential regulation of cytokine production by nitric oxide. Immunology (1993); 80: 146–159
  • Miyajima H., Hirano T., Hirose S., Karasuyama H., Okumura K., Ovary Z. Suppression by IL-2 of IgE production by B cells stimulated by IL-4. J. Immunol (1991); 146: 457–162
  • Monastra G., Bruni A. Decreased serum level of tumor necrosis factor in animals treated with lipopolysaccharide and liposomes containing phosphatidylserine. Lymph. Cytokine Res. (1992); 11: 39–43
  • Moncada S., Palmer R. M.J., Higgs E. A. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol. Rev. (1991); 43: 109–142
  • Mosmann T. R., Coffman R. L. Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol (1989); 7: 145–173
  • Orr J. W., Newton A. C. interaction of protein kinase c with phosphatidylserine. 1. Cooperativity in lipid binding. Biochemistry (1992); 31: 4661–1667
  • Pelassy C., Aussel C., Fehlmann M. Phospholipid metabolism and T cell activation: receptor triggering is associated with the inhibition of phosphatidylserine synthesis. Cell. Signal (1989); 1: 99–105
  • Phillips N. C., Emili A. Immunogenicity of immunoliposomes. Letters in Immunology (1991); 30: 291–296
  • Phillips N. C. Impaired stimulation of anti-bovine serum albumin IgG antibodies by vaccine adjuvants in murine acquired immunodeficiency syndrome. FEMS Microbiol Immunol (1992a); 89: 209–218
  • Phillips N. C. Liposomal carriers for the treatment of acquired immune deficiency syndromes. Bull. Inst. Pasteur (1992b); 90: 205–230
  • Phillips N. C., Emili A. Enhanced antibody response to liposome-associated proteins: preferential stimulation of IgG2a/IgG2b production. Vaccine (1992); 10: 151–158
  • Phillips N. C., Loutfi A., A-Kareem A. M., Shibata H. R., Baines M. G. Clinical evaluation of liposomal tumor antigen vaccines in patients with stage-III melanoma. Cancer Detect. Prevent. (1990); 14: 491–496
  • Phillips N. C., Moras M. L., Chedid L., Lefrancier P., Bernard J. M. Activation of alveolar macrophage tumoricidal activity and eradication of experimental metastases by freeze-dried liposomes containing a new lipophilic muramyl dipeptide. Cancer Res. (1985); 45: 128–134
  • Phillips N. C., Rioux J. D., Tsao M-S. Activation of murine Kupffer cell tumoricidal activity by liposomes containing lipophilic muramyl dipeptide. Hepatology (1988); 8: 1046–1050
  • Quill H., Carlson L., Fox B. S., Weinstein J. N., Schwartz R. H. Optimization of antigen presentation to T cell hybridomas by purified la molecules in planar membranes. J. Immunol. Methods (1987); 98: 29–41
  • Roof R. W., Luescher I. F., Unanue E. R. Phospholipids enhance the binding of peptides to class II major histocompatibility molecules. Proc. Natl. Acad. Sci. USA (1990); 87: 1735–1739
  • Shahum E., ThÉRien H-M. Immunopotentiation of the humoral response by liposomes:encapsulation versus linkage. Immunology (1988); 65: 315–317
  • Storm G., Oussoren C., Peeters P. A.M., Barenholz Y. Tolerability of liposomes in vivo. Liposome Technology, Volume III, G. Gregoriadis. CRC Press, Boca Raton, Florida (1993); 345–383
  • Tan L., Gregoriadis G. Effect of interleukin-2 on the immunoadjuvant action of liposomes. Biochem. Soc. Trans. (1989); 17: 693–694
  • Tzehoval E., Sztein M. B., Goldstein A. L. Thymosins α1, and β4 potentiate the antigen-presenting capacity of macrophages. Immunopharmacology (1989); 18: 107–113
  • Ullrich S. E., Fidler I. J. Liposomes containing muramyl tripeptide phosphatidylethanolamine (MTP-PE) are excellent adjuvants for induction of an immune response to protein and tumor antigens. J. Leukocyte Biol. (1992); 52: 489–494
  • Van Rooijen N., Van Nieuwmegen R. Use of liposomes as biodegradable and harmless adjuvants. Meth. Enzymol. (1983); 93: 83–95
  • Vingerhoets J., Vanham G., Kestens L., Penne G., Leroux-Roels G., Gigase P. Deficient T-cell responses in nonresponders to hepatitis B vaccination: absence of TH1 cytokine production. Immunol. Letts. (1994); 39: 163–168
  • Williams M. E., Chang T. L., Burke S. K., Litchman A. H., Abbas A. K. Activation of functionally distinct subsets of CD4+ lymphocytes. Immunol. Res. (1991); 142: 23–28

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