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Research Article

The Activity of Doxorubicin Niosomes Against an Ovarian Cancer Cell Line and Three in Vivo Mouse Tumour Models

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Pages 399-409 | Received 11 Sep 1995, Accepted 03 Oct 1995, Published online: 28 Sep 2008

References

  • Azmin M. N., Florence A. T., Handjani-Vila R. M., Stuart J. F.B., Vanlerberghe G., Whittaker J. S. The effect of non-ionic surfactant vesicle (niosome) entrapment on the absorption and distribution of methotrexate in mice. J. Pharm. Pharmacol. (1985); 37: 237–242
  • Balazsovits J. A.E., Mayer L. D., Bally M. B., Cullis P. R., McDonnel M., Ginsberg R. S., Falk R. E. Analysis of the effect of liposome encapsulation on the vesicant properties, acute and cardiac toxicities, and antitumour efficacy of doxorubicin. Cancer Chemother. Pharmacol. (1989); 23: 81–86
  • Calabersi P., Chabner B. A. Antineoplastic agents. Goodman and Gilman's Pharmacological Basis of Therapeutics (8th edition), A. Goodman Gilman, T. W. Rail, S. A. Nies, P. Taylor. Pergamon Press, New York (1990); 1209–1263
  • Cowens J. W., Creaven P. J., Greco W. R., Brenner D. E., Tung Y., Ostro M., Ginsberg R., Petrelli N. Initial clinical (phase I) trial of TLC D-99 (doxorubicin encapsulated in liposomes). Cancer Res. (1993); 53: 2796–2802
  • Cuvier C., Roblot-Treupel L., Millot J. M., Lizard G., Chevillard S., Manfait M., Couvreur P., Poupon M. F. Doxorubicin-loaded nanospheres bypass tumour cell multidrug resistance. Biochem. Pharmacol. (1992); 44: 509–517
  • Danhauser-Riedl S., Hausmann E., Schick H-D., Bender R., Dietzfelbinger H., Rastetter J., Hanauske A-R. Phase I clinical and pharmacokinetic trial of dextran conjugated doxorubicin (AD-70, DOX-OXD). Investig. New Drugs (1993); 11: 187–195
  • Duncan R. Drug-polymer conjugates: potential for improved chemotherapy. Anti-Cancer Drugs (1992); 3: 175–210
  • Duncan R., Vasey P., Kaye S. B., Cassidy J. Development of PK1, an HPMA copolymer doxorubicin conjugate, the CRC experience Pavlidis N. Proceedings of the EORTC Early. Drug Development Meeting 1995, Corfu, June, 21–241995. Oncology Department, University of Ionnina, Ionnina, 60–61
  • Florence A. T., Cable C., Cassidy J., Kaye S. B. Non-ionic surfactant vesicles as carriers of doxorubicin. Targeting of Drugs, G. Gregoriadis, A. C. Allison, G. Poste. Plenum Press, New York (1990); 117–126
  • Gabizon A. A. Selective tumour localization and improved therapeutic index of anthracyclines encapsulated in long-circulating liposomes. Cancer Res. (1992); 52: 891–896
  • Gabizon A., Dagan A., Goren D., Barenholz Y., Fuks Z. Liposomes as in vivo carriers of adriamycin: reduced cardiac uptake and preserved antitumour activity in mice. Cancer Res. (1982); 42: 4734–4739
  • Gabizon A., Catane R., Uziely B., Kaufmann B., Safra T, Cohen R., Martin E, Huang A., Barenholz Y. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. (1994); 54: 987–992
  • Haran G., Cohen R., Bar L. K., Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim. Biophys. Acta (1993); 1151: 201–215
  • Harrap K. R., Jones M., Pollard L. A., Kelland L. R. The establishment, characterization and calibration of human ovarian cancer xenografts for the evaluation of novel platinum anticancer drugs. Ann. Oncol. (1990); 1: 65–76
  • Houghton J. A., Houghton P. J. The suitability and use of human tumour xenografts. Rodent Tumour Models in Experimental Cancer Chemotherapy, R. F. Kallman. Pergamon Press, New York (1987); 199–204
  • Huang S. K., Lee K-D., Hong K., Friend D. S., Papahadjopoulos D. Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. Cancer Res. (1992); 52: 5135–5143
  • Katagari Y., Mabuchi K., Itakura T, Naora K., Iwamoto K., Nozu Y., Hirai S., Ikeda N., Kawai T. Adriamycin-lipiodol suspension for i.a. chemotherapy of hepatocellular carcinoma. Cancer Chemother. Pharmacol (1989); 23: 238–242
  • Kerr D. J., Rogerson A., Morrison G. J., Florence A. T., Kaye S. B. Antitumour activity and pharmacokinetics of niosome encapsulated adriamycin in monolayer, spheroid and xenograft. Br. J. Cancer (1988); 58: 432–436
  • Kwon G., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Enhanced tumour accumulation and prolonged circulation times of micelle forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J. Control. Rel (1994); 29: 17–23
  • Lin S-Y, Wu W-H., Lui W-Y. In vitro release, pharmacokinetic and tissue distribution studies of doxorubicin hydrochloride (adriamycin HC1) encapsulated in lipiodolized w/o emulsions and w/o/w multiple emulsions. Pharmazie (1992); 47: 439–443
  • Matsumara Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy; mechanism for tumoritropic accumulation of proteins and the antitumour agent SMANCS. Cancer Res. (1986); 6: 6387–6392
  • Oudard S., Thierry A., Jorgensen T. J., Rahman A. Sensitization of multidrug-resistant colon cancer cells to doxorubicin encapsulated in liposomes. Cancer Chemother. Pharmacol (1991); 28: 259–265
  • Priebe W., Van N. T., Burke T. G., Perez-Soler R. Removal of the basic centre from doxorubicin partially overcomes multidrug resistance and decreases cardiotoxicity. Anti-Cancer Drugs (1993); 4: 37–48
  • Rahman A., Husain S. R., Siddiqui J., Verma M., Agresti M., Center M., Safa A. R., Glazer R. I. Liposome-mediated modulation of multidrug resistance in human HL-60 leukemia cells. J. Natl. Cancer Inst. (1992); 84: 1909–1915
  • Rogerson A., Cummings J., Willmott N., Florence A. T. The distribution of doxorubicin in mice following administration in niosomes. J. Pharm. Pharmacol. (1988); 40: 337–342
  • Sadasivan R., Morgan R., Fabian C., Stephens R. Reversal of multidrug resistance in HL-60 cells by verapamil and liposome-encapsulated doxorubicin. Cancer Lett. (1991); 57: 165–171
  • Sharp S. Y., Rowlands M. G., Jarman M., Kelland L. R. Effects of a new antioestrogen, idoxifene, on cisplatin- and doxorubicin-sensitive and -resistant human ovarian carcinoma cell lines. Br. J. Cancer, 70: 409–414
  • Siemann D. Satisfactory and unsatisfactory tumour models: factors influencing the choice of a tumour model for experimental evaluation. Rodent Tumour Models in Experimental Cancer Chemotherapy, R. F. Kallman. Pergamon Press, New York (1987); 12–15
  • Sikic B. I. Modulation of multidrug resistance: at the threshold. J. Clin. Oncol. (1993); 111: 1629–1635
  • Skehan P., Storeng R., Scudiero D., Monks A., McMahon J., Vistica D., Warren J. T., Bokesh H., Kenney S., Boyd M. R. New colorimetric assay for anticancer-drug screening. J. Natl. Cancer Inst. (1990); 82: 1107–1113
  • Solary E., Bidan J-M., Calvo F., Chauffert B., Calliot D., Mugneret F., Gauville C., Tsuruo T., Carli P-M., Guy H. P-glycoprotein expression and in vitro reversion of doxorubicin resistance by verapamil in clinical specimens from acute leukaemia and myeloma. Leukemia (1991); 5: 592–597
  • Steel G. G. How well do xenografts maintain the therapeutic response characteristics of the source tumour in the donor patient?. Rodent Tumour Models in Experimental Cancer Chemotherapy, R. F. Kallman. Pergamon Press, New York (1987); 205–208
  • Thierry A. R., Jorgensen T. J., Forst D., Belli J. A., Dritschilo A., Rahman A. Modulation of multidrug resistance in Chinese hamster cells by liposome-encapsulated doxorubicin. Cancer Commun. (1989); 1: 311–316
  • Thierry A. R., Dritschilo A., Rahman A. Effect of liposomes on P-glycoprotein function in multidrug resistant cells. Biochem. Biophys. Res. Commun. (1992); 187: 1098–1105
  • Thierry A. R., Vigé D., Coughlin S. S., Belli J. A., Dritschillo A., Rahman A. Modulation of doxorubicin resistance in multidrug-resistant cells by liposomes. FASEB J. (1993); 7: 572–579
  • Uchegbu I. F., Turton J. A., Double J. A., Florence A. T. Drug distribution and a pulmonary adverse effect of intraperitoneally administered doxorubicin niosomes in the mouse. Biopharm. Drug Dispos. (1994); 15: 691–707
  • Uchegbu I. F., Double J. A., Turton J. A., Florence A. T. Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse. Pharm. Res. (1995); 12: 1019–1024
  • Unezaki S., Maruyama K., Ishida O., Takahashi N., Iwatsuru M. Enhanced tumour targeting of doxorubicin by ganglioside GM1-bearing long-circulating liposomes. J. Drug Target. (1993); 1: 287–292
  • Vaage J., Mayhew E., Lasic D., Martin F. Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes. Int. J. Cancer (1992); 51: 942–948
  • Vanlerberghe G., Handjani-Vila R-M., Berthelot C., Sebag H. (1973) Synthèse et activité de surface comparee d'une série de nouveaux dérivé non ioniques. Proceedings of the 6th International Congress on Surface Active Agents. 1972. Carl Hanser, Munchen, 139–155
  • Volm M., Mattern J. Detection of multiple resistance mechanisms in untreated human lung cancer. Onkologie (1993); 16: 189–194
  • Williams S., Alosco T. R., Mayhew E., Lasic D. D., Martin F. J., Bankert R. B. Arrest of human lung tumour xenograft growth in severe combined immunodeficient mice using doxorubicin encapsulated in sterically stabilized liposomes. Cancer Res. (1993); 53: 3964–3967
  • Willmott N., Kamel H. M.H., Cummings J., Stuart J. F.B., Florence A. T. Adriamycin-loaded albumin microspheres: lung entrapment and fate in the rat. Microspheres and Drug Therapy. Pharmaceutical, Immunological and Medical Aspects, S. S. Davis, L. Illum, J. G. McVie, E. Tomlinson. Elsevier Science, London (1984); 205–215
  • Woodcock D. M., Linsenmeyer M. E., Chojnowski G., Kriegler A. B., Nink V, Webster L. K., Sawyer W. H. Reversal of multidrug resistance by surfactants. Br. J. Cancer (1992); 66: 62–68
  • Yeung T. K., Hopewell J. W., Simmonds R. H., Seymour L. W., Duncan R., Bellini O., Grandi M., Spreafico F., Strohalm J., Ulbrich K. Reduced cardiotoxicity of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide conjugates: an experimental study in the rat. Cancer Chemother. Pharmacol. (1991); 29: 105–111
  • Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K., Inoue S. Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res. (1990); 50: 1693–1700
  • Zhang Y., Sweet K. M., Sognier M. A., Belli J. A. An enhanced ability for transforming adriamycin into a noncyto-toxic form in a multidrug-resistant cell line (LZ-8). Biochem. Pharmacol. (1992); 44: 1869–1877

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