References
- M. Ashford, and J. Fell.(1994a). Targeting drugs to the colon: Delivery systems for oral administration J. Drug Targeting 2:241–258.
- M. Ashford, J. Fell, D. Attwood, H. Sharma, and P. Woodhead.(1994b). Studies on pectin formulations for colonic drug delivery J. Controlled. Release 30:225–232.
- H. Brøndsted, and J. Copečeke.(1992). Hydrogels for site‐specific drug delivery to the colon: In vitro and in vivo degradation Pharm. Res 9:1540–1545.
- I. Calder, C. Funder, C. Green, K. Ham, and I. Tange.(1972). Nephrotoxic lesions from 5‐aminosalicylic acid British Medical Journal 1:152–154.
- J. Dressman.(1986). Comparison of canine and human gastrointestinal physiology Pharm. Res 3:123–131.
- R. Geary, and H. Schlameus.(1993). Vancomycin and insulin used as models for oral delivery of peptides J. Controlled Release 23:65–74.
- B. Haeberlin, W. Rubas, H. NolenIII, and D. Friend.(1993). In vitro evaluation of dexamethasone‐β‐D‐glucuronide for colon‐specific drug delivery Pharm. Res 10:1553–1562.
- A. Hawthorne, and C. Hawkey.(1989). Immunosuppressive drugs in inflammatory bowel disease. A review of their mechanisms of efficacy and place in therapy Drugs 38:267–288.
- M. Kennedy, P. Chinwah, and D. Wade.(1979). A pharmacological method of measuring mouth caecal transit time in man Br. J. Clin. Pharmac 8:372–373.
- M. Kraeling, and W. Ritschel.(1992). Development of a colonic release capsule dosage form and the absorption of insulin Meth. Find. Exp. Clin. Pharmacol 14:199–209.
- A. McLeod, L. Tolentino, and T. Tozer.(1994). Glucocorticoid‐dextran conjugates as potential prodrugs for colon‐specific delivery: steady‐state pharmacokinetics in the rat Biopharmaceut. Drug Disposit 15:151–161.
- H. Mizuta, Y. Kawazoe, K. Haga, K. Ogawa, and T. Yokobe.(1989). Determination of small intestinal transit time in beagle dogs using salicylazosulfapyridine Yakugaku Zasshi 109:760–765.
- K. Niwa, T. Takaya, T. Morimoto, and K. Takada.(1995). Preparation and evaluation of a time‐controlled release capsule made of ethylcellulose for colon delivery of drugs J. Drug Targeting 3:83–89.
- M. Peppercorn, and P. Goldman.(1973). Distribution studies of salicylazosulfapyridine and its metabolites Gastroenterology 64:240–245.
- R. Pellicciari, A. Garzon‐Aburbeh, B. Natalini, M. Marinozzi, C. Clerici, G. Gentili, and A. Morelli.(1993). Brush‐border‐enzyme‐mediated intestine‐specific drug delivery. Amino acid prodrugs of 5‐aminosalicylic acid J. Med. Chem 36:4201–4207.
- S. Rao, and W. Ritschel.(1992). Development and in vitro/in vivo evaluation of a colonic release capsule of vasopressin Int. J. Pharm 86:35–41.
- M. Saffran, G. Kumar, C. Savariar, J. Burnham, F. Williams, and D. Neckers.(1986). A new approach to the oral administration of insulin and other peptide drugs Science 233:1081–1084.
- H. Sandberg‐Gertzen, G. Jarnerot, and W. Kraaz.(1986). Azodisal sodium in the treatment of ulcerative colitis. A study of tolerance and relapse‐prevention properties Gastroenterology 90:1024–1030.
- T. Takaya, C. Ikeda, N. Imagawa, K. Niwa, and K. Takada.(1995). Development of a colon delivery capsule and the pharmacological activity of recombinant human granulocyte colony‐stimulating factor (rhG‐CSF) in beagle dogs J. Pharm. Pharmacol 47:474–478.
- P. Watts, C. Wilson, M. Davies, and C. Melia.(1994). Radiolabelling of polymer microspheres for scintigraphic investigations by neutron activation. 4. A pharmacoscintigraphic study of colon‐targeted Eudragit RS‐sulphapyridine microspheres in human volunteers Int. J. Pharm 102:101–108.