Improved Body Distribution of ¹⁴C-labelled AZT bound to Nanoparticles in Rats determined by Radioluminography

References

• Beck P. H., Kreuter J., Miiller W. E.G., Schatton W. Improved peroral delivery of avarol with polybutylcyanoacry-late nanoparticles. Eur. J. Pharm. Biopharm. 1994; 40: 134–137
   Web of Science ®Google Scholar
• Bender A., Schäfer V., Steffan A., Royer C., Kreuter J., Rübsamen-Waigmann H., Briesen H. V. Inhibition of HIV in vitro by antiviral drug-targeting using nanoparticles. Res. Virol. 1994; 145: 215–220
   PubMedGoogle Scholar
• Damge C., Aprahamian M., Balboni G., Hoeltzel A., Andrieu V., Devissaguet J. P. Polyalkylcyanoacrylate nanocapsules increase the intestinal absorption of a lipophilic drug. Int. J. Pharm. 1987; 36: 121–125
   Web of Science ®Google Scholar
• Diepold R., Kreuter J., Himber J., Gurny R., Li V. H.K., Robinson J. R., Saettone M. F., Schnaudigel O. E. Comparison of different models for the testing of pilocarpine eyedrops using conventional eyedrops and a novel depot formulation (nanoparticles). Graefe's Arch. Clin. Exp. Ophthalmol. 1989; 227: 188
   PubMed Web of Science ®Google Scholar
• Eldridge J. H., Hammond C. J., Meulbroek J. A., Staas J. K., Gilley R. M., Tice T. R. Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer's patches. J. Controlled Rel. 1990; 11: 205–214
   Web of Science ®Google Scholar
• Gendelman H. E., Orenstein J. M., Baca L. M., Weiser B., Burger H., Kalter D. C., Meltzer M. S. The macrophage in the persistence and pathogenesis of HIV infection. AIDS 1989; 3: 475–495
   PubMed Web of Science ®Google Scholar
• Grislain L., Couvreur P., Lenaerts V., Roland M., Deprez-Decampeneere D., Speiser P. Pharmacokinetics and distribution of a biodegradable drug-carrier. Int. J. Pharm. 1983; 15: 335–345
   Web of Science ®Google Scholar
• Hamaoka T. Autoradiography of New Era Replacing Traditional X-ray Film. Cell Technology 1990; 9: 456–462
   Google Scholar
• Ilium L. D.S.S., Wilson C. G., Thomas N. W., Frier M., Hardy J. G. Blood clearance and organ deposition of intravenously administered colloidal particles. The effects of particle size, nature, and shape. Int. J. Pharm. 1982; 12: 135–146
   Google Scholar
• Jani P., Halbert W., Langride J., Florence A. T. The uptake and translocation of latex nanospheres and microspheres after oral administration to rats. J. Pharm. Pharmacol. 1989; 41: 809–812
   PubMed Web of Science ®Google Scholar
• Jani P., Halbert G. W., Langridge J., Florence A. T. Nanoparticle uptake by rat gastrointestinal mucosa: quantification and particle size dependency. J. Pharm. Pharmacol. 1990; 42: 821–826
   PubMed Web of Science ®Google Scholar
• Jani P., Nomura T., Yamashita F., Takakura Y., Florence A., Hashida M. Biliary excretion of polystyrene microspheres with covalently linked FITC flurescence after oral and parenteral administration to male Wistar rats. J. Drug Targeting 1996; 4: 87–93
   PubMed Web of Science ®Google Scholar
• Kanekal S., Sahai A., Jones R., Brown D. Storage-phosphor autoradiography: a rapid and highly sensitive method for spatial imaging and quantitation of radioisotopes. J. Pharmacol. Toxicol. Meth. 1995; 33: 171–178
   PubMed Web of Science ®Google Scholar
• Le Ray A. M., Vert M., Gautier J. C., Benoit J. P. Fate of [14 C]poly(DL-lactide-co-glycolide) nanoparticles after intravenous and oral administration to mice. Int. J. Pharm. 1994; 106: 201–211
   Web of Science ®Google Scholar
• Leroux J.-C., Cozens R. M., Roesel J. L., Galli B., Kubel F., Doelker E., Gurny R. Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice. J. Pharm. Sci. 1995; 84: 1387–1391
   PubMed Web of Science ®Google Scholar
• Löbenberg R., Kreuter J. Macrophage-targeting of AZT: A promising strategy for AIDS therapy. AIDS Res. Human Retroviruses 1996; 12: 1709–1715
   PubMed Web of Science ®Google Scholar
• Löbenberg R., Araujo L., Kreuter J. Body distribution of azidothymidine bound to nanooparticles after oral adminiatration. Eur. J. Pharm. Biopharm. 1996a, (in press)
   Google Scholar
• Löbenberg R., Araujo L., Von Briesen H., Rodgers E., Kreuter J. Targeting of azidothymidine bound to hexylcyanoacrylate nanoparticles to macrophages in vivo. J. Control. Rel. 1996b, (in press)
   PubMedGoogle Scholar
• Maincent P., Verge R. L., Sailo P., Couvreur P., Devissaguet J. P. Disposition kinetics and oral bioavailability of vincamine loaded polyalkylcyanoacrylate nanoparticles. J. Pharm. Sci. 1986; 75: 955–958
   PubMed Web of Science ®Google Scholar
• Miyahara J. Visualizing things never seen before. The imaging plate: A new radiation image sensor. Chemistry Today 1989; 223: 29–36
   Google Scholar
• Motoji N., Hayama E., Shigematsu A. Radioluminog-raphy for quantitative autoradiography of 14C. Europ. J. Drug Metabol. Pharmacokin. 1995; 20: 89–105
   PubMed Web of Science ®Google Scholar
• Nefzger M., Kreuter J., Voges R., Liehl E., Czok R. Distribution and elimination of polymethylmethacrylate nanoparticles after peroral administration to rats. J. Pharm. Sci. 1984; 73: 1309–1311
   PubMed Web of Science ®Google Scholar
• O'Hagan D. T. The intsetinal uptake of particles and the implication for drug and antigen delivery. J. Anal. 1996; 189: 477–482
   Google Scholar
• Scherer D., Robison J. R., Kreuter J. Influence of enzymes on the stability of polybutylcyanoacrylate nanoparticles. Int. J. Pharm. 1994; 101: 165–168
   Web of Science ®Google Scholar
• Singer J. M., Adlersberg L., Hoenig E. M., Ende E., Tchorsch Y. Radiolabeled latex particles in the investigation of phagocytosis in vivo: Clearance curves and histological observations. J. Reticuloendothelial Society 1969; 6: 561–589
   PubMedGoogle Scholar
• Tröster S. D., Müller U., Kreuter J. Modification of the body distribution of poly(methylmethacrylate) nanoparticles in rats coating with surfactants. Int. J. Pharm. 1990; 61: 85
   Web of Science ®Google Scholar
• Von Briesen H., Andreesen R., Esser R., Brugger W., Meichsner C., Becke K., Rubsamen-Waigmann H. Infection of monocytes/macrophages by HIV in vitro. Res. Virol. 1990; 141: 225–231
   PubMedGoogle Scholar
• Waser P. G., Müller U., Kreuter J., Berger S., Munz K., Kaiser E., Pfluger B. Localization of colloidal particles (liposomes, hexylcyanoacrylate nanoparticles and albumin nanoparticles) by histology and autoradiography in mice. Int. J. Pharm. 1987; 39: 213–227
   Web of Science ®Google Scholar
• Wood R. W., Li V. H.K., Kreuter J., Robison J. R. Ocular disposition of poly-hexyl-2-cyano[3-14C]acrylate nanoparticles in the albino rabbit. Int. J. Pharm. 1985; 23: 175–183
   Web of Science ®Google Scholar