Benzamide analogue-conjugated polyethylenimine for brain-targeting and gene delivery

References

• Bloomfield VA. (1996). DNA condensation. Curr Opin Struct Biol, 6, 334–341.
   PubMed Web of Science ®Google Scholar
• Boussif O, Lezoualc’h F, Zanta MA, Mergny MD, Scherman D, Demeneix B, Behr JP. (1995). A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc Natl Acad Sci USA, 92, 7297–7301.
   PubMed Web of Science ®Google Scholar
• De Smedt SC, Demeester J, Hennink WE. (2000). Cationic polymer based gene delivery systems. Pharm Res, 17, 113–126.
   PubMed Web of Science ®Google Scholar
• Fischer D, Bieber T, Li Y, Elsässer HP, Kissel T. (1999). A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res, 16, 1273–1279.
   PubMed Web of Science ®Google Scholar
• Bock N, Moll GH, Wicker M, Pilz J, Rüther E, Banaschewski T, Huether G, Rothenberger A. (2004). Early administration of tiapride to young rats without long-lasting changes in the development of the dopaminergic system. Pharmacopsychiatry, 37, 163–167.
   PubMed Web of Science ®Google Scholar
• Hosoya K, Kyoko H, Toyooka N, Kato A, Orihashi M, Tomi M, Tachikawa M. (2008). Evaluation of amino acid-mustard transport as L-type amino acid transporter 1 (LAT1)-mediated alkylating agents. Biol Pharm Bull, 31, 2126–2130.
   PubMed Web of Science ®Google Scholar
• Huang RQ, Qu YH, Ke WL, Zhu JH, Pei YY, Jiang C. (2007). Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. FASEB J, 21, 1117–1125.
   PubMed Web of Science ®Google Scholar
• Huang R, Ke W, Han L, Liu Y, Shao K, Jiang C, Pei Y. (2010). Lactoferrin-modified nanoparticles could mediate efficient gene delivery to the brain in vivo. Brain Res Bull, 81, 600–604.
   PubMed Web of Science ®Google Scholar
• Huang R, Ke W, Han L, Liu Y, Shao K, Ye L, Lou J, Jiang C, Pei Y. (2009). Brain-targeting mechanisms of lactoferrin-modified DNA-loaded nanoparticles. J Cereb Blood Flow Metab, 29, 1914–1923.
   PubMed Web of Science ®Google Scholar
• Huwyler J, Wu D, Pardridge WM. (1996). Brain drug delivery of small molecules using immunoliposomes. Proceedings of the National Academy of Sciences of the United States of America, 93, 14164–14169.
   Google Scholar
• Jones AR, Shusta EV. (2007). Blood-brain barrier transport of therapeutics via receptor-mediation. Pharm Res, 24, 1759–1771.
   PubMed Web of Science ®Google Scholar
• Ke W, Shao K, Huang R, Han L, Liu Y, Li J, Kuang Y, Ye L, Lou J, Jiang C. (2009). Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. Biomaterials, 30, 6976–6985.
   PubMed Web of Science ®Google Scholar
• Levey AI, Hersch SM, Rye DB, Sunahara RK, Niznik HB, Kitt CA, Price DL, Maggio R, Brann MR, Ciliax BJ. (1993). Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proc Natl Acad Sci USA, 90, 8861–8865.
   PubMed Web of Science ®Google Scholar
• Liu Y, Li J, Shao K, Huang R, Ye L, Lou J, Jiang C. (2010). A leptin derived 30-amino-acid peptide modified pegylated poly-L-lysine dendrigraft for brain targeted gene delivery. Biomaterials, 31, 5246–5257.
   PubMed Web of Science ®Google Scholar
• Farde L, Ehrin E, Eriksson L, Greitz T, Hall H, Hedström CG, Litton JE, Sedvall G. (1985). Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography. Proc Natl Acad Sci USA, 82, 3863–3867.
   PubMed Web of Science ®Google Scholar
• Louis MH, Dutoit S, Denoux Y, Erbacher P, Deslandes E, Behr JP, Gauduchon P, Poulain L. (2005). Intraperitoneal linear polyethylenimine (L-PEI)-mediated gene delivery to ovarian carcinoma nodes in mice. Cancer Gene Ther, 13, 367–374.
   Web of Science ®Google Scholar
• Mach RH, Huang Y, Freeman RA, Wu L, Vangveravong S, Luedtke RR. (2004). Conformationally-flexible benzamide analogues as dopamine D3 and [sigma]2 receptor ligands. Bioorganic & Medicinal Chemistry Letters, 14, 195–202.
   PubMed Web of Science ®Google Scholar
• Meng Q, Yu M, Gu B, Li J, Liu Y, Zhan C, Xie C, Zhou J, Lu W. (2010). Myristic acid-conjugated polyethylenimine for brain-targeting delivery: In vivo and ex vivo imaging evaluation. J Drug Target, 18, 438–446.
   PubMed Web of Science ®Google Scholar
• Merdan T, Kunath K, Petersen H, Bakowsky U, Voigt KH, Kopecek J, Kissel T. (2005). PEGylation of poly (ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice. Bioconjug Chem, 16, 785–792.
   PubMed Web of Science ®Google Scholar
• Pardridge WM. (2002). Drug and gene targeting to the brain with molecular Trojan horses. Nat Rev Drug Discov, 1, 131–139.
   PubMed Web of Science ®Google Scholar
• Pardridge WM. (2005). The blood-brain barrier: Bottleneck in brain drug development. NeuroRx, 2, 3–14.
   PubMedGoogle Scholar
• Pettersson I, Liljefors T. (1992). Conformational analysis of dopamine D-2 receptor antagonists of the benzamide series in relation to a recently proposed D-2 receptor-interaction model. J Med Chem, 35, 2355–2363.
   PubMed Web of Science ®Google Scholar
• Risau W, Wolburg H. (1990). Development of the blood-brain barrier. Trends Neurosci, 13, 174–178.
   PubMed Web of Science ®Google Scholar
• Sokolova V, Neumann S, Kovtun A, Chernousova S, Heumann R, Epple M. (2010). An outer shell of positively charged poly (ethyleneimine) strongly increases the transfection efficiency of calcium phosphate/DNA nanoparticles. Journal of Materials Science, 45, 4952–4957.
   Web of Science ®Google Scholar
• Son S, Hwang DW, Singha K, Jeong JH, Park TG, Lee DS, Kim WJ. (2010). RVG peptide tethered bioreducible polyethylenimine for gene delivery to brain. J Control Release, (In Press).
   Web of Science ®Google Scholar
• Takano A, Suhara T, Yasuno F, Suzuki K, Takahashi H, Morimoto T, Lee YJ, Kusuhara H, Sugiyama Y, Okubo Y. (2006). The antipsychotic sultopride is overdosed–a PET study of drug-induced receptor occupancy in comparison with sulpiride. Int J Neuropsychopharmacol, 9, 539–545.
   PubMed Web of Science ®Google Scholar
• Tu Z, Xu J, Chu W, Li S, Luedtke R, Mach R. (2008). Fluorine-18 labeled benzamide analogues as dopamine D3 receptor PET radiotracers. J Nucl Med Meeting Abstracts, 49, (Supple 1):142P.
   Google Scholar
• Uchino H, Kanai Y, Kim DK, Wempe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H. (2002). Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): Insights into the mechanisms of substrate recognition. Mol Pharmacol, 61, 729–737.
   PubMed Web of Science ®Google Scholar
• Ulasov AV, Khramtsov YV, Trusov GA, Rosenkranz AA, Sverdlov ED, Sobolev AS. (2011). Properties of PEI-based polyplex nanoparticles that correlate with their transfection efficacy. Mol Ther, 19, 103–112.
   PubMed Web of Science ®Google Scholar
• Wagner E, Cotten M, Foisner R, Birnstiel ML. (1991). Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci USA, 88, 4255–4259.
   PubMed Web of Science ®Google Scholar
• Zhan C, Yan Z, Xie C, Lu W. (2010). Loop 2 of Ophiophagus Hannah Toxin b Bind with Neuronal nAChRs and Enhance Intracranial Drug Delivery. Mol Pharm, 6;7, 1940–1947.
   Google Scholar