Octreotide-mediated tumor cell uptake and intracellular pH-responsive drug delivery of the self-assembly supramolecular nanocarrier

References

• Karathanasis E, Chan L, Balusu SR, et al. Multifunctional nanocarriers for mammographic quantification of tumor dosing and prognosis of breast cancer therapy. Biomaterials 2008;29:4815–22
   PubMed Web of Science ®Google Scholar
• Gao Y, Gu W, Chen L, et al. A multifunctional nano device as non-viral vector for gene delivery: in vitro characteristics and transfection. J Control Release 2007;118:381–8
   PubMed Web of Science ®Google Scholar
• Wan F, You J, Sun Y, et al. Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro. Int J Pharm 2008;359:104–10
   PubMed Web of Science ®Google Scholar
• Guo M, Que C, Wang C, et al. Multifunctional superparamagnetic nanocarriers with folate-mediated and pH-responsive targeting properties for anticancer drug delivery. Biomaterials 2011;32:185–94
   PubMed Web of Science ®Google Scholar
• Hong M, Zhu S, Jiang Y, et al. Novel anti-tumor strategy: PEG-hydroxycamptothecin conjugate loaded transferrin-PEG-nanoparticles. J Control Release 2010;141:22–9
   PubMed Web of Science ®Google Scholar
• Bae Y, Kataoka K. Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation. J Control Release 2006;116:e49–50
   PubMed Web of Science ®Google Scholar
• Gao ZG, Lee DH, Kim DI, Bae YH. Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice. J Drug Target 2005;13:391–7
   PubMed Web of Science ®Google Scholar
• Lehn JM. Toward self-organization and complex matter. Science 2002;295:2400–03
   PubMed Web of Science ®Google Scholar
• Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv Drug Deliv Rev 2001;47:113–31
   PubMed Web of Science ®Google Scholar
• Satoh T, Higuchi Y, Kawakami S, et al. Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids’ release control. J Control Release 2009;136:187–95
   PubMed Web of Science ®Google Scholar
• Bae Y, Fukushima S, Harada A, Kataoka K. Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. Angew Chem Int Ed Engl 2003;42:4640–3
   PubMed Web of Science ®Google Scholar
• Bae Y, Nishiyama N, Fukushima S, et al. Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy. Bioconjug Chem 2005b;16:122–30
   PubMed Web of Science ®Google Scholar
• Capurso G, Panzuto F, Delle Fave G. Clinical relevance of the expression of somatostatin receptors in digestive endocrine tumours. Dig Liver Dis 2010;42:173–4
   PubMedGoogle Scholar
• Hillel PG, van Beek EJ, Taylor C, et al. The clinical impact of a combined gamma camera/CT imaging system on somatostatin receptor imaging of neuroendocrine tumours. Clin Radiol 2006;61:579–87
   PubMed Web of Science ®Google Scholar
• Watt HL, Kharmate G, Kumar U. Biology of somatostatin in breast cancer. Mol Cell Endocrinol 2008;286:251–61
   PubMed Web of Science ®Google Scholar
• Na DH, Murty SB, Lee KC, et al. Preparation and stability of poly (ethylene glycol) (PEG)ylated octreotide for application to microsphere delivery. AAPS Pharm Sci Tech 2003;4:E72
   PubMedGoogle Scholar
• Olson BJ, Markwell J. Assays for determination of protein concentration. Curr Protoc Protein Sci 2007;Chapter 3:Unit 3.4
   PubMedGoogle Scholar
• Wang CH, Hsiue GH. Polymeric micelles with a pH-responsive structure as intracellular drug carriers. J Control Release 2005;108:140–9
   PubMed Web of Science ®Google Scholar
• Speelmans G, Staffhorst RW, de Kruijff B, de Wolf FA. Transport studies of doxorubicin in model membranes indicate a difference in passive diffusion across and binding at the outer and inner leaflets of the plasma membrane. Biochemistry 1994;33:13761–8
   PubMed Web of Science ®Google Scholar
• Yoo HS, Park TG. Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer. J Control Release 2001;70:63–70
   PubMed Web of Science ®Google Scholar
• Hovorka O, St'astny M, Etrych T, et al. Differences in the intracellular fate of free and polymer-bound doxorubicin. J Control Release 2002;80:101–17
   PubMed Web of Science ®Google Scholar
• Awasthi VD, Garcia D, Goins BA, Phillips WT. Circulation and biodistribution profiles of long-circulating PEG-liposomes of various sizes in rabbits. Int J Pharm 2003;253:121–32
   PubMed Web of Science ®Google Scholar
• Sheng Y, Liu C, Yuan Y, et al. Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan. Biomaterials 2009;30:2340–8
   PubMed Web of Science ®Google Scholar
• Kajiwara E, Kawano K, Hattori Y, et al. Long-circulating liposome-encapsulated ganciclovir enhances the efficacy of HSV-TK suicide gene therapy. J Control Release 2007;120:104–10
   PubMed Web of Science ®Google Scholar
• Shao K, Huang R, Li J, et al. Angiopep-2 modified PE-PEG based polymeric micelles for amphotericin B delivery targeted to the brain. J Control Release 2010;147:118–26
   PubMed Web of Science ®Google Scholar
• Li SD, Huang L. Nanoparticles evading the reticuloendothelial system: role of the supported bilayer. Biochim Biophys Acta 2009;1788:2259–66
   PubMed Web of Science ®Google Scholar
• Kulaksiz H, Eissele R, Rossler D, et al. Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies. Gut 2002;50:52–60
   PubMed Web of Science ®Google Scholar
• Singh V, Brendel MD, Zacharias S, et al. Characterization of somatostatin receptor subtype-specific regulation of insulin and glucagon secretion: an in vitro study on isolated human pancreatic islets. J Clin Endocrinol Metab 2007;92:673–80
   PubMed Web of Science ®Google Scholar
• Wu JX, Yuan YZ, Xu JY, et al. Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis. Chin J Dig Dis 2004;5:35–9
   PubMedGoogle Scholar
• Maeda H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 2001;41:189–207
   PubMedGoogle Scholar
• Caliceti P, Veronese FM. Pharmacokinetic and biodistribution properties of poly (ethylene glycol)-protein conjugates. Adv Drug Deliv Rev 2003;55:1261–77
   PubMed Web of Science ®Google Scholar
• Rossi J, Giasson S, Khalid MN, et al. Long-circulating poly (ethylene glycol)-coated emulsions to target solid tumors. Eur J Pharm Biopharm 2007;67:329–38
   PubMed Web of Science ®Google Scholar
• Fang J, Sawa T, Maeda H. Factors and mechanism of “EPR” effect and the enhanced antitumor effects of macromolecular drugs including SMANCS. Adv Exp Med Biol 2003;519:29–49
   PubMed Web of Science ®Google Scholar
• Han HD, Lee A, Song CK, et al. In vivo distribution and antitumor activity of heparin-stabilized doxorubicin-loaded liposomes. Int J Pharm 2006;313:181–8
   PubMed Web of Science ®Google Scholar
• MacEwan SR, Callahan DJ, Chilkoti A. Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery. Nanomedicine (Lond) 2010;5:793–806
   PubMed Web of Science ®Google Scholar
• Yoo HS, Park TG. Folate receptor targeted biodegradable polymeric doxorubicin micelles. J Control Release 2004;96:273–83
   PubMed Web of Science ®Google Scholar
• Lee ES, Na K, Bae YH. Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor. J Control Release 2005;103:405–18
   PubMed Web of Science ®Google Scholar
• Bae Y, Jang WD, Nishiyama N, et al. Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery. Mol Biosyst 2005;1:242–50
   PubMed Web of Science ®Google Scholar
• Ko J, Park K, Kim YS, et al. Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly (beta-amino ester) block copolymer micelles for cancer therapy. J Control Release 2007;123:109–15
   PubMed Web of Science ®Google Scholar
• Park S, Yoo HS. In vivo and in vitro anti-cancer activities and enhanced cellular uptakes of EGF fragment decorated doxorubicin nano-aggregates. Int J Pharm 2010;383:178–85
   PubMed Web of Science ®Google Scholar
• Di Donato A, Ghiggeri GM, Di Duca M, et al. Lysyl oxidase expression and collagen cross-linking during chronic adriamycin nephropathy. Nephron 1997;76:192–200
   PubMed Web of Science ®Google Scholar
• Zeidan Q, Strauss M, Porras N, Anselmi G. Differential long-term subcellular responses in heart and liver to adriamycin stress. Exogenous L-carnitine cardiac and hepatic protection. J Submicrosc Cytol Pathol 2002;34:315–21
   PubMedGoogle Scholar