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Endothelium
Journal of Endothelial Cell Research
Volume 1, 1993 - Issue 3
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Original Article

Reversible Inhibition of Inducible, but Not Constitutive, Nitric Oxide Synthase by NG -Nitro-L-Arginine in Rat Aorta

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Pages 141-145 | Received 02 Oct 1993, Published online: 13 Jul 2009

References

  • Auguet M., Guillon J. M., Delaflotte S., Etiemble E., Chabrier P. E., Braquet P. Endothelium-independent protective effect of N -monomethyl-L-arginine on endotoxin-induced alterations of vascular reactivity. Life Sciences 1991; 48: 189–193
  • Auguet M., Lonchampt M. O., Delaflotte S., Goulin-Schultz J., Chabrier P. E., Braquet P. Induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in vascular smooth muscle cells. FEBS Letters 1992a; 297: 183–185
  • Auguet M., Delaflotte S., Chabrier P. E., Braquet P. Endothelial and smooth muscle NO synthase in rat isolated aorta. In Biology of nitric oxide, S. Moncada, M. A. Marietta, J. B. Hibbs. Portland Press. 1992b; 211–213
  • Beasley D., Schwartz J. H., Brenner B. M. Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells. Journal of Clinical Investigation 1991; 87: 602–608
  • Bogle R. G., Moncada S., Pearson J. D., Mann G. E. Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter. British Journal of Pharmacology 1992; 105: 768–770
  • Dwyer M. A., Bredt D. S., Snyder S. H. Nitric oxide synthase: irreversible inhibition by L-N -nitroarginine in brain in vitro and in vivo. Biochemical and Biophysical Research Communications 1991; 176: 1136–1141
  • Fleming I., Gray G. A., Julou-Schaeffer G., Parrat J. R., Stoclet J. C. Incubation with endotoxin activates the L-arginine pathway in vascular tissue. Biochemical and Biophysical Research Communications 1990; 171: 562–568
  • Kilbourn R. G., Jubran A., Gross S. S., Griffith O. W., Levi R., Adams J., Lodato R. F. Reversal of endotoxin-mediated shock by NG-Methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochemical and Biophysical Research Communications 1990; 172: 1132–1138
  • Moore P. K., Al-Swayeh O. A., Chong N. W. S., Evans R. A., Gibson A. L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro. British Journal of Pharmacology 1990; 99: 408–412
  • Moritoki H., Takeuchi S., Hisayama T., Kondoh W. Nitric oxide synthase responsible for L-arginine-induced relaxation of rat aortic rings in vitro may be an inducible type. Br. J. Pharmacol. 1992; 107: 361–366
  • Mülsch A., Busse R. Nitric oxide synthesis in endothelial cytosol : evidence for a calcium-dependent and calcium-independent mechanism. Naunyn Schmiedebergs Archives of Pharmacology 1990; 341: 143–147
  • Nava E., Palmer R. M. J., Moncada S. The role of nitric oxide in endotoxin shock. Journal of Vascular Research 1992; 29: 172
  • Palmer R. M. J., Ashton D. S., Moncada S. Vascular endothelial cells synthetize nitric oxide from L-arginine. Nature 1988; 333: 664–666
  • Rees D. D., Cellek S., Palmer R. M. J., Moncada S. Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone : an insight into shock. Biochemical and Biophysical Research Commununication 1990; 173: 541–547
  • Rotoli B. M., Bussolati O., Dall' Asta V., Gazzola G. C. The transport of L-arginine in Chinese hamster ovary cells. Biochemical and Biophysical Research Communications 1989; 164: 1093–1098
  • Christensen H. N., Kilberg M. S. Amino acid transport across the plasma membrane : role of regulation in interor-gan flows, in amino acid transport in animal cells., D. L.O. Yudilevich. C. A. R. Boyd University Press, ManchesterUK 1985; 10–46
  • Wright C. E., Rees D. D., Moncada S. Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovascular Research 1992; 26: 48–57

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