Chronic L-arginine Prevents Cholesterol-attenuation of Vasodilation to Acetylcholine and Serotonin

References

• Alsip N. L., Harris P. D. Serotonin-induced dilation of small arterioles is not mediated via endothelium-derived relaxing factor in skeletal muscle. European Journal Pharmacology 1992; 229: 117–124
   PubMed Web of Science ®Google Scholar
• Cayatte A. I., Palacino J. I., Horten K., Cohen R. A. Chronic inhibition of nitric oxide production accelerates neointima formation and impaires endothelial function in hypercholesterolemic rabbits. Arterioscler. Thromb 1994; 14: 753–759
   PubMedGoogle Scholar
• Chester A. H., O'Neil G. S., Moncada S., Tadjkariiimi S., Yacoub M. N. Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arterioles. Lancet 1990; 336: 897–900
   PubMed Web of Science ®Google Scholar
• Cho-Chung Y. S., Clair T., Bodwin J. S., Hill D. M. Arrest of mammary tumor growth in vivo by L-Arginine: stimulation of NAD-dependent activation of adenylate cyclase. Biochemistry and Biophysics Research Commun 1980; 95: 1306–1313
   PubMed Web of Science ®Google Scholar
• Cooke J. P., Andon N. A., Girerd X. J., Hirsch A. T., Creager M. A. Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta. Circulation 1991; 83: 1057–1062
   PubMed Web of Science ®Google Scholar
• Cooke J. P., Singer A. H., Tsao P., Zera P., Rowan R. A., Billingham M. E. Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit. J. Clin. Invest 1992; 90: 1168–1172
   PubMed Web of Science ®Google Scholar
• Creager M. A., Gallagher S. J., Girerd X. J., Coleman S. M., Dzau V. J., Cooke J. P. L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. Journal of Clinical Investigation 1992; 90: 1248–1253
   PubMed Web of Science ®Google Scholar
• Girerd X. J, Hirsch A. T., Cooke J. A., Dzau V. J., Creager M. A. L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits. Circulation Research 1990; 67: 1301–1308
   PubMed Web of Science ®Google Scholar
• Guerra R., Jr, Brotherton A. F. A., Goodwin P. J., Clark C. R., Armstrong M. D., Harrison D. G. Mechanisms ot abnormal endothelium-dependent vascular relaxation in atherosclerosis: implications for altered autocrine and paracrine functions of EDRF. Blood vessels 1989; 26: 300–314
   PubMedGoogle Scholar
• Ignarro L. J., Burke T. M., Wood K. S., Kadowitz P. J. Association between cyclic GMP accumulation and ace tylcholine elicited relaxation of bovine intrapulmonary artery. Journal of Pharmacology and Experimental Therapy 1984; 228: 682–690
   PubMed Web of Science ®Google Scholar
• Kaley G., Rodenburg J. M., Messina E. J., Wolin M. S. Endotheium-associated vasodilators in rat skeletal muscle microcirculation. American Journal of Physiology 1989; 256: H720–H725
   PubMed Web of Science ®Google Scholar
• Lüscher T. F. Imbalance of endothelium-derived ralaxing and contracting factors: A new concept in hypertension. American Journal of Hypertension 1990; 3: 317–330
   PubMed Web of Science ®Google Scholar
• Merkel L. A., Rivera L. M., Bilder G. E., Perrone M. H. Differential alteration of vascular reactivity in rabbit aorta with modest elevation of serum cholesterol. Circulation Research 1990; 67: 550–555
   PubMed Web of Science ®Google Scholar
• Miller F. N., Joshua I. G., Anderson G. L. Quantitation of vasodilator-induced micromolecular leakage by in vivo fluorescent microscopy. Microvasc. Res 1982; 24: 56–67
   PubMed Web of Science ®Google Scholar
• Milner J. A. Arginine: a dietary modifier of ammonia detoxification and pyrimidine biosynthesis. Absorption and Utilization of Amino Acids, M. Friedman. CRC Press, Boca Raton 1989; Vol II.: 25–40
   Google Scholar
• Palmer R. M. J., Ashton D. S., Moncada S. Vascular endothelial cells syntheize nitric oxide from L-Arginine. Nature 1988; 333: 664–666
   PubMed Web of Science ®Google Scholar
• Rossitch E., Jr, Alexander E., III., McBlack P. L., Cooke J. P. L-Arginine normalized endothelial function in cerebral vessels fromhypercholesterolemic rabbits. Journal of Clinical Investigation 1991; 87: 1295–1299
   PubMed Web of Science ®Google Scholar
• Schuschke D. A., Joshua I. G., Miller F. N. A comparison of early microcirculatory and aortic changes in hypercholesterolemic rats. Arteriosclerosis and Thrombosis 1991; 11: 154–160
   PubMedGoogle Scholar
• Schuschke D. A., Miller F. N., Lominadze D. G., Feldhoff R. C. L-arginine restores cholesterol-attenuated micro-vascular responses in the rat cremaster. International Journal of Microcirculation Clinical and Experimental 1994; 14: 204–211
   PubMedGoogle Scholar
• Shimokawa H., Vanhoutte P. M. Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hyper-cholesterolemia and atherosclerocis. Circulation Research 1989; 64: 900–914
   PubMed Web of Science ®Google Scholar
• Wang B. -Y., Singer A. H., Tsao P. S., Drexler H., Kosek J., Cooke J. P. Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit. J. Am. Coll. Cardiol 1994; 23: 452–458
   PubMed Web of Science ®Google Scholar