Publication Cover
Endothelium
Journal of Endothelial Cell Research
Volume 5, 1997 - Issue 3
5
Views
21
CrossRef citations to date
0
Altmetric
Original Article

Role of Adenosine in the Hypoxic Induction of Vascular Endothelial Growth Factor in Porcine Brain Derived Microvascular Endothelial Cells

, , , &
Pages 155-165 | Received 29 Nov 1996, Accepted 04 Mar 1997, Published online: 13 Jul 2009

References

  • Adair T. H., Gay W. J., Montani J. P. Growth regulation of the vascular system: evidence for a metabolic hypothesis. American Journal of Physiolology 1990; 259: R393–R404
  • Berne R. M., Rubio R., Curnish R. R. Release of adenosine from ischemic brain. Effect on cerebral vascular resistance and incorporation into cerebral adenine nucleotides. Circulation Research 1974; 35: 262–271
  • Bontemps P., Vincent M. F., Van den Berghe G. Mechanisms of elevation of adenosine levels in anoxic hepatocytes. Journal of Biochemistry 1993; 290: 671–677
  • Chomczynski P., Sachhi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 1987; 162: 156–159
  • Claffey K. P., Wilkison W. O., Spiegelman B. M. Vascular Endothelial Growth Factor: Regulation by cell differentiation and activated second messenger pathways. Journal of Biological Chemistry 1992; 267: 16317–16322
  • Cornfold E. M., Braun L. D., Crane P. D., Oldendorf W. Blood-brain barrier restriction of peptides and the low uptake of enkephalins. Endocrinology 1978; 103: 1297–1303
  • Crone C. The permeability of brain capillaries to non-electrolytes. Acta Physiologica Scandinavica 1965; 64: 407–417
  • Dragunow M., Faull R. L. M. Neuroprotective effects of adenosine. Trends of Pharmacological Science 1988; 9: 194
  • Dusseau J. W., Hutchins P. M., Malbasa D. S. Stimulation of angiogenesis by adenosine on chick chorioallantoic membrane. Circulation Research 1986; 59: 163–170
  • Faquin W. C., Schneider T. J., Goldberg M. A. Modulators of protein kinase C inhibit hypoxia-induced erythropoietin production. Experimental Hematology 1993; 21: 420–426
  • Ferrara N., Henzel W. J. Pituitary follicular cells secrete a novel Heparin-binding growth factor specific for vascular endothelial cells. Biochemical and Biophysical Research Communications 1989; 161: 851–858
  • Ferrara N., Houck K. A., Jakeman L. B., Winer J., Leung D. W. the vascular endothelial growth factor family of polypeptides. Journal of Cellular Biochemistry 1991; 47: 211–218
  • Fischer S., Sharma H. S., Karliczek G. F., Schaper W. Expression of vascular permeability factor/vascular endothelial growth factor in pig cerebral microvascular endothelial cells and its upregulation by adenosine. Molecular Brain Research 1995; 28: 141–148
  • Forsythe J. A., Jiang B. -H., Iyer N. V., Agani F., Leung S. W., Koos R. D., Semenza G. L. Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1. Molecular and Cellular Biology 1996; 16: 4604–4613
  • Goldberg M. A., Dunning S. P., Bunn H. F. Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein. Science 1988; 242: 1412–1415
  • Goldberg M. A., Schneider T. J. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. Journal of Biological Chemistry 1994; 269: 4355–4359
  • Greenberg M. E., Bender T. P. Identification of newly transcribed RNA. Current protocols in molecular biology, F. M. Ausubel, R. E. Kingston. Harvard medical school: Wiley interscience. 1994; 10.1–10.11
  • Hashimoto E., Kage K., Ogita T., Nakaoka T., Matsuoka R., Kira Y. Adenosine as an endogenous mediator of hypoxia for induction of vascular endothelial growth factor mRNA in U-937 cells. Biochemical and Biophysical Research Communication 1994; 204: 318–324
  • Hashimoto E., Kage K., Ogita T., Nakaoka T., Matsuoka R., Kira Y. Adenosine as an endogenous mediator of ischemia for enhancement of vascular endothelial growth factor messenger ribonucleic acid in rat heart. Circulation 1994; 90: 1–521
  • Hatashita S., Hoff J. T. Brain edema and cerebrovascular permeability during cerebral ischemia in rats. Stroke 1990; 21: 582–588
  • Hentze M. W. Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells. Biochimica and Biophysica Acta 1991; 1090: 281–292
  • Ijichi A., Sakuma S., Tofilon P. J. Hypoxia-Induced Vascular Endothelial Growth Factor Expression in Normal Rat Astrocyte Cultures. Glia 1995; 14: 87–93
  • Keck P. J., Hauser S. D., Krivi G., Sanzo K., Warren T., Feder J., Connolly D. T. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989; 246: 1309–1312
  • Klausner R. D., Rouault T. A., Harford J. B. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 1993; 72: 19–28
  • Knighton D. R., Hunt T. K., Scheuenstuhl H., Halliday B. J., Werb Z., Banda M. J. Oxygen tension regulates the expression of angiogenesis factor by macrophages. Science 1983; 221: 1283–1285
  • Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
  • Leung D. W., Cachianes G., Kuang W. J., Goeddel D. V., Ferrara N. Vascular Endothelial Growth Factor is a secreted angiogenic mitogen. Science 1989; 246: 1306–1309
  • Lindholm D., Heumann R., Hengerer B., Thoenen H. J. Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts. Journal of Biological Chemistry 1988; 263: 16348–16351
  • Loike J. D., Cao L., Brett J., Ogawa S., Silverstein S. C., Stern D. Hypoxia induces glucose transporter expression in endothelial cells. American Journal of Physiology 1992; 263: C326–C333
  • Meininger C. J., Schelling M. E., Granger H. J. Adenosine and hypoxia stimulate proliferation and migration of endothelial cells. American Journal of Physiology 1988; 255: H554–H562
  • Minchenko A., Salceda S., Bauer T., Caro J. Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cellular and Molecuar Biological Research 1994; 40: 35–39
  • Mischek U., Meyer J., Galla H. -J. Characterization of γ-glutamyl transpeptidase activity of cultured endothelial cells from porcine brain capillaries. Cell and Tissue Research 1989; 256: 221–226
  • O'Brien M. D., Jordan M. M., Waltz A. G. Ischemic cerebral edema and the blood-brain barrier. Archives of Neurology 1974; 30: 461–465
  • Olesen S. -P. Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition. Brain Research 1986; 368: 24–29
  • Plate K. H., Breier G., Weich H. A., Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas. Nature 1992; 359: 845–848
  • Rapoport S. -I., Ohno K., Pettigrew K. D. Drug entry into the brain. Brain Research 1979; 172: 354–359
  • Schubert P., Kreutzberg G. W. Neuroprotective mechanisms of endogenous adenosine action and pharmacological implications. Pharmacology of cerebral Ischemia, J. Krieglstein, H. Oberpichler. Wiss. Verlagsgesellschaft, Stuttgart 1990; 417–426
  • Semenza G. L., Wang G. L. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Molecular and Cellular Biology 1992; 12: 5447–5454
  • Sharma H. S., Sassen L., Verdouw P. D., Schaper W. Induced expression of a potent mitogen, vascular endothelial growth factor during ischemic preconditioning. Journal of Molecular and Cellular Cardiology 1992; 24(Suppl V)189, (abstract)
  • Shaw G., Kamen R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 1986; 46: 659–667
  • Shima D. T., Deutsch U., Damore P. A. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in messenger ma stability. FEBS Letters 1995; 370: 203–208
  • Shweiki D., Itin A., Soffer D., Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843–845
  • Shyu A. -B., Greenberg M. E., Belasco J. G. The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes Development 1989; 3: 60–72
  • Svensjo E., Grega G. J. Evidence for endothelial cellmediated regulation of macromolecular permeability by postcapillary venules. Federation Proceedings 1986; 45: 89–95
  • Toullet D., Pianette P., Coste H., Bellevergue P., Grand-Ferret T., Ajakane M., Baudet V., Boissin P., Boursier E., Loriolle F., Duhamel L., Charon D., Kirilovsky J. The Bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. Journal of Biological Chemistry 1991; 266: 15771–15781
  • van Daele P., van Coevorden A., Roger P. P., Boeynaems J. -M. Effects of adenine nucleotides on the proliferation of aortic endothelial cells. Circulation Research 1991; 70: 82–90
  • Voyta J. C., Via D. P., Butterfield C. E., Zetter B. R. Isolation and identification of endothelial cells based on their increased uptake of acetylated low density lipoprotein. Journal of Cellular Biology 1984; 99: 2034–2040
  • Yeo T. -K., Senger D. R., Dvorak H. F., Freter L., Yeo K. -T. Glycosylation is essential for efficient secretion but not for permeability-enhancing activity of vascular permeability factor. Biochemical and Biophysical Research Communication 1991; 179: 1568–1575

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.