Role of Tyrosine Phosphorylation in Thrombin-Induced Endothelial Cell Contraction and Barrier Function

References

• Akiyama T., Ishida J., Nakagawa S., Ogawara H., Watanabe S., Itoh N., Shibuva M, Fukami Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. Journal of Biological Chemistry 1987; 262: 5592–5595
   PubMed Web of Science ®Google Scholar
• Akiyama T., Ogawara H. Use and specificity of genistein as inhibitor of protein tyrosine kinases. Methods in Enzymology 1991; 201: 362–370
   PubMed Web of Science ®Google Scholar
• Asahi M., Yamagi, Ohta S., Inazu T., Sakai K., Takeuchi F., Taniguchi T., Yamamura H. Thrombin-induced human platelet aggregation is inhibited by protein-tyrosine kinase inhibitors. St 638 and genistein. FEBS Letters 1992; 309: 10–14
   PubMed Web of Science ®Google Scholar
• Beretz A., Stoclet J., Anton R. Inhibition of isolated rat aorta contraction by flavonoids: Possible correlation with cyclic AMP phosphodiesterase inhibition. Planta Medica 1980; 39: 236–237
   Web of Science ®Google Scholar
• Berk B. C., Alexander R. W., Brock T. A., Gimbrone M. A., Webb R. C. Vasoconstriction: a new action for platelet-derived growth factor. Science 1986; 232: 87–90
   PubMed Web of Science ®Google Scholar
• Berk B. C., Brock T. A., Webb R. C., Taubman M. B., Atkinson W. J., Gimbrone M. A., Alexander R. W. Epidermal growth factor: a vascular smooth muscle mitogen, induces rat aortic contraction. Journal of Clinical Investigation 1985; 75: 1083–1086
   PubMed Web of Science ®Google Scholar
• Di Salvo J., Pfitzer G., Semenchuk L. A. Protein tyrosine phosphorylation, cellular Ca2+, and Ca2+ sensitivity for contraction of smooth muscle. Canadian Journal of Physiological Pharmacology 1994; 72: 1434–1439
   PubMed Web of Science ®Google Scholar
• Di Salvo J., Semenchuk L. A., Lauer J. Vanadate-induced contraction of smooth muscle and enhanced protein tyrosine phosphorylation. Archives of Biochemistry and Biophysics 1993; 304: 386–391
   PubMed Web of Science ®Google Scholar
• Di Salvo J., Steusloft A., Semenchuk L., Satoh S., Kolguist K, Pfitzer G. Tyrosine kinase inhibitors suppress agonist induced contraction in smooth muscle. Biochemical and Biophysical Research Communications 1993; 190: 968–974
   PubMed Web of Science ®Google Scholar
• Durieu-Trautmann O, Chaverot S C, Cazaubon S, Strosberg A D, Couraud P-O. Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells. J Bio Chem 1994; 17: 12536–12540
   Google Scholar
• Fantl W. J., Johnson D. E., Williams L. T. Signalling by receptor tyrosine kinases. Annual Reviews of Biochemistry 1993; 62: 453–481
   PubMed Web of Science ®Google Scholar
• Fleming I., Fisslthaler B., Busse R. Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen-activated protein kinases. Circulation Research 1995; 76: 522–529
   PubMed Web of Science ®Google Scholar
• Fleming I., Fisslthaler B, Busse R. Interdependence of calcium signaling and protein tyrosine phosphorylation in human endothelial cells. Journal of Biological Chemistry 1996; 271: 11009–11015
   PubMed Web of Science ®Google Scholar
• Gallagher D. J., Garcia J. G.N., Herring B. P. Expression of a novel myosin light chain kinase in embryonic tissues and cultured cells. Journal of Biological Chemistry 1995; 270: 29090–29095
   PubMed Web of Science ®Google Scholar
• Garcia J. G.N., Birnboim A. S., Bizios R., Del Vecchio P. J., Fenton J. W., Malik A. B. Thrombin- induced increases in albumin clearance across cultured endothelial monolayers. Journal of Cellular Physiology 1986; 128: 96–104
   PubMed Web of Science ®Google Scholar
• Garcia I. G.N., Davis H. W., Patterson C. E. Regulation of endothelial cell gap formation and barrier dysfunction: role of myosin light chain phosphorylation. Journal of Cellular Physiology 1995; 163: 510–522
   PubMed Web of Science ®Google Scholar
• Garcia J. G.N, Gilbert-McClain L. I. Regulation of myosin phosphorylation and barrier function in endothelium. Pulmonary Edema, K. Weir, J. T. Reeves. Futura Publishing Company, Armonk, New York 1998; 18: 261–273
   Google Scholar
• Garcia J. G.N., Lazar V, Gilbert-McClain L. I., Gallagher P. J., Verin A. D. Myosin light chain kinase in endothelium: Molecular cloning and regulation. American Journal of Respiratory Cell and Molecular Biology 1997a; 16: 489–494
   PubMed Web of Science ®Google Scholar
• Garcia J. G.N., Patterson C. E., Bahler C., Aschner J., Hart C. M., English D. Thrombin receptor activating peptides induce Ca++ mobilization, barrier dysfunction, prostaglandin synthesis and platelet-derived growth factor mRN A expression in cultured endothelium. Journal of Cellular Physiology 1993; 156: 541–549
   PubMed Web of Science ®Google Scholar
• Garcia J. G.N., Schaphorst K. L., Shi S., Verin A. D., Hart C M., Callahan K. S., Patterson C. E. Mechanisms of ionomycin-induced endothelial cell barrier dysfunction. American Journal of Physiology: Lung Cellular and Molecular Physiology 1997b; 17: LI72–L184
   Google Scholar
• Garcia J. G.N, Schaphorst K. L. Regulation of endothelial cell gap formation and paracellular permeability. Journal of Investigative Medicine 1995; 43(2)117–126
   PubMed Web of Science ®Google Scholar
• Gilbert-McClain L. I, Verin A. D, Cook C. D, Garcia J. G.N. Regulation of endothelial cell myosin light chain kinase activity by tyrosine phosphatases. J Cell Biochem 1998; 10: 141–155
   Google Scholar
• Groden D. L, Guan Z, Stokes B. T. Determination of fura-2 dissociation constants following adjustment of the apparent Ca-EGTA association constant for temperature and ionic strength. Cell Calcium 1991; 12: 279–287
   PubMed Web of Science ®Google Scholar
• Irwin R. P., Lin S. Z., Roganski M. A., Purdy R. H., Paul S. M. Steroid potentiation and inhibition of N-Methyl-O-Aspartate receptor-mediated intracellular Ca++responses. Structure-activity studies. Journal of Pharmacology Exp Ther 1994; 271: 677–682
   PubMed Web of Science ®Google Scholar
• Kruse H. J., Negrescu E. V., Weber P. C., Siess W. Thrombin-induced Ca2+influx and protein tyrosine phosphorylation in endothelial cells is inhibited by herbimycin A. Biochemical and Biophysical Research Communications 1994; 202: 1651–1656
   PubMed Web of Science ®Google Scholar
• Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacterio-phage T4. Nature 1970; 227: 680–685
   PubMed Web of Science ®Google Scholar
• Lum H., Malik A. B. Regulation of vascular endothelial barrier function. American Journal of Physiology: Lung Cellular and Molecular Physiology 1994; 267: L223–L241
   PubMed Web of Science ®Google Scholar
• Marsen T. A., Simonson M. S., Dunn M. J. Thrombin induces the preproendothelin-1 gene in endothelial cells by a protein tyrosine kinase-linked mechanism. Circulation Research 1995; 76: 987–995
   PubMed Web of Science ®Google Scholar
• Merkel L. A., Rivera L. M., Colussi D. J., Perron M. H. Inhibition of EGF-induced vasoconstriction in isolated rabbit aortic rings with the tyrosine kinase inhibitor RG 50864. Biochemical and Biophysical Research Communications 1993; 192: 1319–1326
   PubMed Web of Science ®Google Scholar
• Molloy C. J., Taylor D. S., Weber H. Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells. Journal of Biological Chemistry 1993; 268: 7338–7345
   PubMed Web of Science ®Google Scholar
• Moy A. B., Shasby S. S., Scott B. D., Shasby D. M. The effect of histamine and cyclic adenosine monophosphate on myosin light chain phosphorylation in human umbilical vein endothelial cells. Journal of Clinical Investigation 1993; 92: 1198–1206
   PubMed Web of Science ®Google Scholar
• Morgan K. G., Defeo T. T., Wene K., Weinstien R. Alterations of excitation-contraction compling by platelet-derived growth factor in enzymatically isolated and cultured vascular smooth muscle cells. Pfluegers Archiv European Journal of Physiology 1985; 405: 77–79
   PubMed Web of Science ®Google Scholar
• Ozaki Y., Yatomi Y., Jinnai Y., Kume S. Effects of genistein, a tyrosine kinase inhibitor, on platelet functions. Genistein attenuates thrombin-induced Ca2+ mobilization in human platelets by affecting polyphosphoinositide turnover. Biochem Pharmacol 1993; 46(3)395–403
   PubMed Web of Science ®Google Scholar
• Patterson C. E., Davis H. W., Schaphorst K. L., Garcia J. G.N. Mechanisms of cholera toxin prevention of thrombin- and PMA- induced endothelial cell barrier dysfunction. Microvascular Research 1994; 48: 212–235
   PubMed Web of Science ®Google Scholar
• Patterson C. E., Rhoades R. A., Garcia J. G.N. Evans blue-albumin binding as a new marker of transendothelial macromolecule permeability. Journal of Applied Physiology 1992; 72: 865–873
   PubMed Web of Science ®Google Scholar
• Ramsby M. L., Makowski G. S., Khairallah E. A. Differential detergent fractionation of isolated hepatocytes: biochemical, immunochemical and two-dimensional gel electrophoresis characterization of cytoskeletal and noncytoskeletal compartments. Electrophoresis. 1994; 15: 265–277
   PubMed Web of Science ®Google Scholar
• Sargent P., Farndale R. W., Sage S. O. ADP-and Thapsigargin-evoked Ca2+entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2, 5-dihydroxycinnamate in fura-2-loaded human platelets. Journal of Biological Chemistry 1993; 268(24)18151–18156
   PubMed Web of Science ®Google Scholar
• Schägger H., Von Yagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of protein in the range from 1 to 100 kDa. Analytical Biochemistry 1987; 166: 368–379
   PubMed Web of Science ®Google Scholar
• Schaphorst K. L., Pavalko F., Patterson C. E., Garcia J. G.N. Thrombin-mediated barrier dysfunction in endothelium. Role of adhesion protein phosphorylation. American Journal of Respiratory Cell and Molecular Biology 1997; 17: 441–455
   Google Scholar
• Shasby D. M., Shasby S. S., Sullivan J. M., Peach M. J. Role of endothelial cell cytoskeleton in control of endothelial permeability. Circulation Research 1982; 51: 657–661
   PubMed Web of Science ®Google Scholar
• Stasek J. E., Patterson C. E., Garcia J. G.N. Protein kinase C phosphorylates caldesmon77 and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers. Journal of Cellular Physiology 1992; 153: 62–75
   PubMed Web of Science ®Google Scholar
• Tiruppathi C., Malik A. B., Del Vecchio P., Keese C. R., Giaever I. Electrical method for detection of endothelial cell shape change in real lime: Assessment of endothelial barrier function. Proceedings of the National Academy of Sciences USA 1992; 89: 7919–7923
   PubMed Web of Science ®Google Scholar
• Treuner M., Bohmer F. D., Schulze W., Petuchov S. P., Grosse R. Limited selectivity of a synthetic erbstatin derivative for tyrosine kinase and cell growth inhibition. Biochemical International 1992; 26(4)617–625
   PubMedGoogle Scholar
• Tsuda T., Kawahara Y., Shii K., Koide M., Ishida Y., Yokoyama M. Vasoconstrictor-induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells. FEBS Letters 1991; 285
   Google Scholar
• Umezawa K., Hori T., Tajima H., Itoh M., Issiki K., Tekeuchi T. Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors. FEBS Letters 1990; 260: 198–200
   PubMed Web of Science ®Google Scholar
• Umezawa K., Imoto M. Use of erbstatin as a protein tyrosine kinase inhibitor. Methods in Enzymology 1991; 201: 379–385
   PubMed Web of Science ®Google Scholar
• Verin A. D., Cooke C., Patterson C. E., Garcia J. G.N. Role of Ca2+/calmodulin-dependent phosphatase 2B in thrombin-induced endothelial cell contractile responses. Am. J Physiol: Lung Cell Molec Physiology 1998a, in press
   Web of Science ®Google Scholar
• Verin A. D., Gilbert-McClain L. I., Garcia J. G.N. Biochemical characterization and regulation of the 214 kDa endothelial cell myosin light chain kinase. American Journal of Respiratory Cell and Molecular Biology 1998b, in press
   Google Scholar
• Verin A. D., Patterson C. E., Day M. E., Garcia J. G.N. Regulation of endothelial cell gap formation and barrier function by myosin-associated phosphatase activities. American Journal of Physiology: Lung Cellular and Molecular Physiology 1995; 269: L99–L108
   PubMed Web of Science ®Google Scholar
• Villa-Moruzzi E., Zonca P. D., Crabb J. W. Phosphorylation of the catalytic subunit of type-1 protein phosphatase by the v-abl tyrosine kinase. FEBS Letters 1991; 293: 67–71
   PubMed Web of Science ®Google Scholar
• Wysolmerski R. B., Lagunoff D. Involvement of myosin light chain kinase in endothelial cell retraction. Proceedings of the National Academy of Sciences USA 1990; 87: 16–20
   PubMed Web of Science ®Google Scholar
• Yang S. G., Saifeddine M., Hollenbery M. O. Tyrosine kinase inhibitors and the contractile action of epidermal growth factor, urogastrone and other agonists in gastric smooth muscle. Canadian Journal of Physiology and Pharmacology 1992; 70: 85–93
   PubMed Web of Science ®Google Scholar