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Research Article

Pathophysiology of Chronic Nitric Oxide Synthase Inhibition-Induced Fetal Growth Restriction in the Rat

, DO, , BS, , MS & , PhD
Pages 28-36 | Published online: 26 May 2010

REFERENCES

  • Wight E, Küng CF, Moreau P, Takase H, Lüscher TF. Chronic blockade of nitric oxide-synthase and endothelin receptors during pregnancy in the rat: effect on pregnancy outcome. J Soc Gynecol Investig 1998; 5:132–139.
  • Thaete LG, Neerhof MG, Silver RK. Differential effects of endothelin A and B receptor antagonism on fetal growth in normal and nitric oxide-deficient rats. J Soc Gynecol Investig 2001; 8:18–23.
  • Helmbrecht GD, Farhat MY, Lochbaum L, Brown HE, Yadgarova KT, Eglington GS, L-arginine reverses the adverse pregnancy changes induced by nitric oxide synthase inhibition in the rat. Am J Obstet Gynecol 1996; 175:800–805.
  • Diket AL, Pierce MR, Munshi UK, Voelker CA, Eloby-Childress S, Greenberg SS, Nitric oxide inhibition causes intrauterine growth retardation and hind-limb disruptions in rats. Am J Obstet Gynecol 1994; 171:1243–1250.
  • Thaete LG, Kushner DM, Dewey ER, Neerhof MG. Endothelin and the regulation of uteroplacental perfusion in nitric oxide synthase inhibition-induced fetal growth restriction. Placenta 2005; 26:242–250.
  • Edwards DL, Arora CP, Bui DT, Castro LC. Long-term nitric oxide blockade in the pregnant rat: Effects on blood pressure and plasma levels of endothelin-1. Am J Obstet Gynecol 1996; 175:484–488.
  • Neerhof MG, Thaete LG. Chronic NOS-inhibition-induced IUGR is associated with increased circulating endothelin-1 levels in the rat. Hypertens Pregnancy 1997; 16:319.
  • Wu-Wong JR, Dixon DB, Chiou WJ, Sorensen BK, Liu G, Jae H-S, Tasker A, von Geldern TW, Winn M, Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A‐182086 and A-192621: in vitro studies. Clin Sci 2002; 103(Suppl. 48):107S–111S.
  • Wu-Wong JR, Dixon DB, Chiou WJ, Dayton BD, Novosad EI, Adler AL, Pharmacology of A-216546: a highly selective antagonist for endothelin ETA receptor. Eur J Pharmacol 1999; 366:189–201.
  • Mayr AJ, Lederer W, Wolf HJ, Dünser M, Pfaller K, Mörtl MG. Morphologic changes of the uteroplacental unit in preeclampsia-like syndrome in rats. Hypertens Pregnancy 2005; 24:29–37.
  • Bahtiyar MO, Buhimschi CS, Ravishankar V, Julien SD, Copel JA, Norwitz ER, Nitric oxide (NO) inhibition and hypoxia significantly alters maternal serum angiogenic factors in a rat model of preeclampsia. J Soc Gynecol Investig 2005; 12(Suppl.):269A (Abstract #580).
  • Miller MJS, Voelker CA, Olister S, Thompson JH, Zhang X-J, Rivera D, Fetal growth retardation in rats may result from apoptosis: role of peroxynitrite. Free Radical Biol Med 1996; 21:619–629.
  • Haynes WG, Ferro CJ, O'Kane KPJ, Somerville D, Lomax CC, Webb DJ. Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in humans. Circulation 1996; 93:1860–1870.
  • Weber C, Schmitt R, Birnboeck H, Hopfgartner G, van Marle SP, Peeters PAM, Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects. Clin Pharmacol Ther 1996; 60:124–137.
  • Krum H, Viskoper RJ, Lacourciere Y, Budde M, Charlon V. The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. New Engl J Med 1998; 338:784–790.
  • Opgenorth TJ, Wessale JL, Dixon DB, Adler AL, Calzadilla SV, Padley RJ, Effects of endothelin receptor antagonists on the plasma immunoreactive endothelin-1 level. J Cardiovasc Pharmacol 2000; 36(Suppl 1):S292–S296.

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