Advanced search
Publication Cover
Hypertension in Pregnancy Volume 30, 2011 - Issue 4
Submit an article Journal homepage
119
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Genetic Variation of Myeloperoxidase Gene Contributes to Preeclampsia: A Preliminary Association Study in Turkish Population

Ebru OzturkDepartment of Obstetrics and Gynecology, Faculty of Medicine, Gaziantep University, Gaziantep, TurkeyCorrespondence[email protected]
, MD,
Ozcan BalatDepartment of Obstetrics and Gynecology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
, MD,
Sacide PehlivanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey;Department of Medical Biology and Genetics, Gaziantep University, Gaziantep, Turkey
,
Mete Gurol UgurDepartment of Obstetrics and Gynecology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
, MD &
Tugce SeverDepartment of Medical Biology and Genetics, Gaziantep University, Gaziantep, Turkey
, PhD
Pages 377-383 | Published online: 09 Aug 2011

REFERENCES

  • Cunningham FG, Lindheimer MD. Hypertension in pregnancy. N Eng J Med 1992; 326:927–932.
  • Vita JA, Brennan ML, Gokce N, . Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation 2004; 110:1134–1139.
  • Mellembakken JR, Hogasen K, Mollnes TE, . Increased systemic activation of neutrophils but not complement in preeclampsia. Obstet Gynecol 2001; 97:371–374.
  • Noyan T, Güler A, Sekeroglu MR, Kamac0 M. Serum advanced oxidation protein products, myeloperoxidase and ascorbic acid in preeclampsia and eclampsia. Aust N Z J Obstet Gynaecol 2006; 46:486–491.
  • Gandley RE, Rohlan J, Zhou Y, . Increased myeloperoxidase in the placenta and circulation of women with preeclampsia. Hypertension 2008; 52:387–393.
  • Austin GE, Lam L, Zaki SR, . Sequence comparison of putative regulatory DNA of the 59 flanking region of the myeloperoxidase gene in normal and leukemic bone marrow cells. Leukemia (Baltimore) 1993; 7:1445–1450.
  • Saygili EI, Aksoy N, Pehlivan M, . Enzyme levels and G-463A polymorphism of myeloperoxidase in chronic lymphocytic leukemia and multiple myeloma. Leuk Lymphoma 2009; 50:2030–2037.
  • Davey DA, MacGillivray I. The classification and definition of the hypertensive disorders of pregnancy. Am J Obstet Gynecol 1988; 158:892–898.
  • London SJ, Lehman TA, Taylor JA. Myeloperoxidase genetic polymorphism and lung cancer risk. Cancer Res 1997; 57:5001–5003.
  • Mendell NR, Simon GA. A general expression for the variance-covariance matrix of estimates of gene frequency: The effects of departures from Hardy-Weinberg equilibrium. Ann Hum Genet 1984; 48:283–286.
  • Roberts JM, Hubel CA. Is oxidative stress the link in the two-stage model of pre-eclampsia? Lancet 1999; 354:788–789.
  • Bretelle F, Sabatier F, Shojai R, . New insight in physiopathology of preeclampsia and intra-uterine growth retardation: Role of inflammation. Gynecol Obstet Fertil 2004; 32:482–489.
  • Holthe MR, Staff AC, Berge LN, Fagerhol MK, Lyberg T. Calprotectin plasma level is elevated in preeclampsia. Acta Obstet Gynecol Scand 2005; 84:151–154.
  • Redman CW, Sacks GP, Sargent IL. Preeclampsia: An excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999; 180:499–506.
  • Beckmann I, Efraim SB, Vervoort M, Visser W, Wallenburg HC. Tumor necrosis factor-alpha in whole blood cultures of preeclamptic patients and healthy pregnant and nonpregnant women. Hypertens Pregnancy 2004; 23:319–329.
  • Holthe MR, Staff AC, Berge LN, Lyberg T. Leukocyte adhesion molecules and reactive oxygen species in preeclampsia. Obstet Gynecol 2004; 103:913–922.
  • Malle E, Furtmüller PG, Sattler W, Obinger C. Myeloperoxidase: A target for new drug development? Brit J Pharmacol 2007; 152:838–854.
  • Kour H, Perkins MJ. The free radical chemistry of food additives. In: Aruoma OI, Halliwell B, eds. Free Radicals and Food Additives, New York, 1991.
  • Barrette WC, Hannum DM, Wheeler WD, Hurst JK. General mechanism for the bacterial toxicity of hypochlorous acid: Abolition of ATP production. Biochemistry 1989; 28:9172–9178.
  • Marcinkievicz J, Chain B, Nowak B, . Antimicrobial and cytotoxic activity of hypochlorous acid: Interactions with taurine and nitrite. Inflamm Res 2000; 49:280–289.
  • Abu-Soud HM, Hazen SL. Nitric oxide is a physiological substrate for mammalian peroxidases. J Biol Chem 2000; 275:37524–37532.
  • Zhang C, Patel R, Eiserich JP, . Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid. Am J Physiol Heart Circ Physiol 2001; 281:H1469–H1475.
  • Abu-Soud HM, Khassawneh MY, Sohn JT, . Peroxidases inhibit nitric oxide (NO) dependent bronchodilation: Development of a model describing NO-peroxidase interactions. Biochemistry 2001; 40:11866–11875.
  • Bowen RS, Moodley J, Dutton MF, Fickl H. Systemic inflammatory indices in pre-eclampsia and eclampsia. J Obstet Gynaecol 2001; 21:563–569.
  • Kim YJ, Park HS, Park MH, Suh SH, Pang MG. Oxidative stress-related gene polymorphism and the risk of preeclampsia. Eur J Obstet Gynecol Reprod Biol 2005; 119:42–46.
  • Akar ME, Eyi EG, Yilmaz ES, Yuksel B, Yilmaz Z. Maternal deaths and their causes in Ankara, Turkey, 1982–2001. J Health Popul Nutr 2004; 22:420–428.
  • Akbayram S, Sari N, Akgün C, . The frequency of consanguineous marriage in eastern Turkey. Genet Couns 2009;20: 207–214.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.