Genome-wide methylation profiling demonstrates hypermethylation in maternal leukocyte DNA in preeclamptic compared to normotensive pregnancies

References

• Tost J. DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Mol Biotechnol 2010;44:71–81
   PubMed Web of Science ®Google Scholar
• Bourque DK, Avila L, Penaherrera M, et al. Decreased placental methylation at the H19/IGF2 imprinting control region is associated with normotensive intrauterine growth restriction but not preeclampsia. Placenta 2010;31:197–202
   PubMed Web of Science ®Google Scholar
• Yuen RK, Avila L, Penaherrera MS, et al. Human placental-specific epipolymorphism and its association with adverse pregnancy outcomes. PLoS One 2009;4:e7389
   Web of Science ®Google Scholar
• Yuen RK, Penaherrera MS, von Dadelszen P, et al. DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia. Eur J Hum Genet 2010;18:1006–12
   PubMed Web of Science ®Google Scholar
• Zhao A, Cheng Y, Li X, et al. Promoter hypomethylation of COMT in human placenta is not associated with the development of pre-eclampsia. Mol Hum Reprod 2011;17:199–206
   PubMed Web of Science ®Google Scholar
• Chiu RW, Chim SS, Wong IH, et al. Hypermethylation of RASSF1A in human and rhesus placentas. Am J Pathol 2007;170:941–50
   PubMed Web of Science ®Google Scholar
• Bellido ML, Radpour R, Lapaire O, et al. MALDI-TOF mass array analysis of RASSF1A and SERPINB5 methylation patterns in human placenta and plasma. Biol Reprod 2010;82:745–50
   PubMed Web of Science ®Google Scholar
• Avila L, Yuen RK, Diego-Alvarez D, et al. Evaluating DNA methylation and gene expression variability in the human term placenta. Placenta 2010;31:1070–7
   PubMed Web of Science ®Google Scholar
• Kulkarni A, Chavan-Gautam P, Mehendale S, et al. Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia. DNA Cell Biol 2011;30:79–84
   PubMed Web of Science ®Google Scholar
• Bell CG, Teschendorff AE, Rakyan VK, et al. Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. BMC Med Genomics 2010;3:33
   PubMed Web of Science ®Google Scholar
• Sun Z, Chai HS, Wu Y, et al. Batch effect correction for genome-wide methylation data with Illumina Infinium platform. BMC Med Genomics 2011;4:84
   PubMed Web of Science ®Google Scholar
• Teschendorff AE, Menon U, Gentry-Maharaj A, et al. Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res 2010;20:440–6
   PubMed Web of Science ®Google Scholar
• Available online at: www.genego.com [last accessed Jul 2010]
   Google Scholar
• White WM, Brost BC, Sun Z, et al. Normal early pregnancy: A transient state of epigenetic change favoring hypomethylation. Epigenetics 2012;7:729–34
   PubMed Web of Science ®Google Scholar
• Quentmeier H, Tonelli R, Geffers R, et al. Expression of BEX1 in acute myeloid leukemia with MLL rearrangements. Leukemia 2005;19:1488–9
   Google Scholar
• Pike BL, Greiner TC, Wang X, et al. DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status. Leukemia 2008;22:1035–43
   PubMed Web of Science ®Google Scholar
• Bouchard L, Thibault S, Guay SP, et al. Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy. Diabetes Care 2010;33:2436–41
   PubMed Web of Science ®Google Scholar
• Katari S, Turan N, Bibikova M, et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet 2009;18:3769–78
   PubMed Web of Science ®Google Scholar
• Muller HM, Ivarsson L, Schrocksnadel H, et al. DNA methylation changes in sera of women in early pregnancy are similar to those in advanced breast cancer patients. Clin Chem 2004;50:1065–8
   Google Scholar
• Dionisio L, Jose De Rosa M, Bouzat C, Esandi Mdel C. An intrinsic GABAergic system in human lymphocytes. Neuropharmacology 2011;60:513–19
   PubMed Web of Science ®Google Scholar
• Nicholson AC, Unger ER, Mangalathu R, et al. Exploration of neuroendo-crine and immune gene expression in peripheral blood mononuclear cells. Brain Res Mol Brain Res 2004;129:193–7
   PubMedGoogle Scholar
• Mohr S, Liew CC. The peripheral-blood transcriptome: new insights into disease and risk assessment. Trends Mol Med 2007;13:422–32
   PubMed Web of Science ®Google Scholar
• Mougeot JL, Li Z, Price AE, et al. Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway. BMC Med Genomics 2011;4:74
   Google Scholar
• Plummer PN, Colson NJ, Lewohl JM, et al. Significant differences in gene expression of GABA receptors in peripheral blood leukocytes of migraineurs. Gene 2011;490:32–6
   Google Scholar
• Dammann G, Teschler S, Haag T, et al. Increased DNA methylation of neuropsychiatric genes occurs in borderline personality disorder. Epigenetics 2011;6:1454–62
   PubMed Web of Science ®Google Scholar
• Silver H, Susser E, Danovich L, et al. SSRI augmentation of antipsychotic alters expression of GABA(A) receptor and related genes in PMC of schizophrenia patients. Int J Neuropsychopharmacol 2011;14:573–84
   Google Scholar
• Bischoff FZ, Sinacori MK, Dang DD, et al. Cell-free fetal DNA and intact fetal cells in maternal blood circulation: Implications for first and second trimester non-invasive prenatal diagnosis. Hum Reprod 2002;8:493–500
   Google Scholar
• Rakyan VK, Down TA, Balding DJ, Beck S. Epigenome-wide association studies for common human diseases. Nat Rev Genet 2011;12:529–41
   PubMed Web of Science ®Google Scholar
• Liu YJ, Papasian CJ, Liu JF, et al. Is replication the gold standard for validating genome-wide association findings? PLoS One 2008;3:e4037
   Google Scholar