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Research Article

Attenuation of hyperglycemia-induced apoptotic signaling and anti-angiogenic milieu in cultured cytotrophoblast cells

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Pages 159-169 | Received 01 Sep 2015, Accepted 15 Nov 2015, Published online: 01 Mar 2016

References

  • Anderson UD, Olsson MG, Kristensen KH, Akerstrom B, Hansson SR. Review: biochemical markers to predict preeclampsia. Placenta. 2012;33( Suppl.):S42–S47.
  • Pridjian G, Puschett JB. Preeclampsia. Part I: clinical and pathophysiological considerations. Obstet Gynecol Surv. 2002;57:598–618.
  • Yu Y, Jenkins AJ, Nankervis AJ, et al. Antiangiogenic factors and pre-eclampsia in type 1 diabetic women. Diabetologia. 2009;52:160–168.
  • Uddin MN, Beeram MR, Kuehl TJ. Diabetes mellitus and preeclampsia. Med J Obstet Gynecol. 2013;1:1016.
  • Combs EA, Rosenn B, Kitzmiller JL, et al. Early-pregnancy proteinuria in diabetes related to preeclampsia. Obstet Gynecol. 1993;82:802–807.
  • Fox H. The placenta in pregnancy hypertension. In: Rubin PC, ed. Handbook of Hypertension. Hypertension in Pregnancy. Vol. 10. New York: Elsevier; 1988:16–37.
  • [No authors listed] Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol. 2000;183:S1–S22.
  • Zhou Y, Fisher SJ, Janatpour M, et al. Human cytotrophoblasts adopt a vascular phenotype as they differentiate: a strategy for successful endovascular invasion? J Clin Invest. 1997;99:2139–2151.
  • Harris LK, Keogh RJ, Wareing M, et al. Invasive trophoblasts stimulate vascular smooth muscle cell apoptosis by a fas ligand-dependent mechanism. Am J Pathol. 2006; 169:1863–1874.
  • Chang L, Karin M. Mammalian MAP kinase signaling cascades. Nature. 2001;410:37–40.
  • Garrington TP, Johnson GL. Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol. 1999;11:211–218.
  • Kolch W. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J. 2000;351:289–305.
  • Kyriakis JM, Avruch J. Mammalian mitogen activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev. 2001;81:807–869.
  • Nebreda AR, Porras A. p38 MAP kinases: beyond the stress response. Trends Biochem Sci. 2000;25:257–260.
  • Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB. Examination of the cellular mechanisms by which marinobufagenin inhibits cytotrophoblast function. J Biol Chem. 2008;283:17946–17953.
  • Zauberman A, Zipori D, Krupsky M, Ben-Levy R. Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of STAT3. Oncogene. 1999;18:388–393.
  • Barak Y, Nelson MC, Ong ES, et al. PPARgamma is required for placental, cardiac, and adipose tissue development. Mol Cell. 1999;4:585–595.
  • Marvin KW, Eyholt RL. The 15-deoxy-D12. 14-prostaglandin J2 receptor, peroxisome proliferator-activated receptor-gamma (PPARgamma) is expressed in human gestational tissues and is functionally active in JEG3 choriocarcinoma cells. Placenta. 2000;21:436–440.
  • Schaiff WT, Carlson MG, Smith SD, Levy R, Nelson DM, Sadovsky Y. Peroxisome proliferator activated receptor-gamma modulates differentiation of human trophoblast in a ligand-specific manner. J Clin Endocrinol Metab. 2000;85:3874–3881.
  • McCarthy FP, Drewlo S, Kingdom J, Johns EJ, Walsh SK, Kenny LC. Peroxisome proliferator-activated receptor-g as a potential therapeutic target in the treatment of preeclampsia. Hypertension. 2011;58:280–286.
  • Cawyer CR, Horvat D, Leonard D, et al. Hyperglycemia impairs cytotrophoblast function via stress signaling. Am J Obstet Gynecol. 2014;211:541.e1–541. e8.
  • Athanassiades A, Hamilton GS, Lala PK. Vascular endothelial growth factor stimulates proliferation but not migration or invasiveness inhuman extravillous trophoblast. Biol Reprod. 1998;59:643–654.
  • Crocker IP, Strachan BK, Lash GE, Cooper S, Warren AY, Barker PN. Vascular endothelial growth factor but not placental growth factor promotes trophoblast syncytialization in vitro. J Soc Gynecol Invest. 2001;8:341–346.
  • Torry DS, Hinrichs M, Torry R. Determinants of placental vascularity. Am J Reprod Immunol. 2004;51:257–268.
  • Maglione D, Guerriero V, Viglietto G, et al. Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene on chromosome 14. Oncogene. 1993;8:925–931.
  • Venkatesha S, Toporsian M, Lam C, et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med. 2006;12:642–649.
  • Allaire, AD, Ballenger KA, Wells SR, McMahon MJ, Lessey BA. Placental apoptosis in preeclampsia. Obstet Gynecol. 2000;96:271–276.
  • Smith SC, Baker PN, Symonds EM. Placental apoptosis in normal human pregnancy. Am J Obstet Gynecol. 1997;177:57–65.
  • Donovan M, Cotter TG. Control of mitochondrial integrity by BCL-2 family members and caspase-independent cell death. Biochimica et Biophysica Acta. 2003;1644(2004):133–147.
  • Sorenson CM. Review BCL-2 family members and disease. Biochimica et Biophysica Acta. 2003;1644(2004):169–177.
  • Ratts VS, Tao XJ, Webster CB, et al. Expression of BCL-2, BAX and BAK in trophoblast layer of term human placenta: a unique model of apoptosis within a syncytium. Placenta. 2000;21:361–366.
  • Genbacev O, DiFederico E, McMaster M, Fisher SJ. Invasive cytotrophoblast apoptosis in pre-eclampsia. Human Repro. 1999;14:59–66.
  • Cobellis L, DeFalco M, Torella M, et al. Modulation of bax expression in physiological and pathological human placentas throughout pregnancy. In Vivo. 2007;21:777–784.
  • Otto JC, Smith WL. Prostaglandin endoperoxide synthase-1 and -2. J Lipid Med Cell Sign. 1995;13:139–156.
  • Smith WL, Garavito M, DeWitt DL. Prostaglandin endoperoxide H synthases (Cycloxygenase)-1 and -2. J Bio Chem. 1996;271:33157–33160.
  • Zhou L, Xue H, Wang Z, et al. Angiotensin-(1e7) attenuates high glucoseinduced proximal tubular epithelial-tomesenchymal transition via inhibiting ERK1/2 and p38 phosphorylation. Life Sci. 2012;90:454–462.
  • Desoye G, Mouzon SH, Shafrir E. The placenta in diabetic pregnancy. In: Hod M, Jovanovic L, Di Renzo GC, Leiva A, Langer O, eds. Textbook of Diabetes and Pregnancy. London: Martin Dunitz; 2003:126–143.

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