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Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy Volume 8, 1989 - Issue 1
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Original Article

Plasma 19-Hydroxyandrostenedione in Hypertensive Diseases of Pregnancy-Influence of Delivery and Betamethasone

M. E. Hähnel Department of Obstetrics and Gynaecology, University of Western Australia King Edward Memorial Hospital for Women Subiaco, Western Australia, 6008, Australia
,
J. D. Martin Department of Obstetrics and Gynaecology, University of Western Australia King Edward Memorial Hospital for Women Subiaco, Western Australia, 6008, Australia
&
R. Hähnel Department of Obstetrics and Gynaecology, University of Western Australia King Edward Memorial Hospital for Women Subiaco, Western Australia, 6008, Australia
Pages 13-24 | Published online: 07 Jul 2009

References

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  • Martin J. D., Hähnel M. E., Hähnel R. Plasma androstenedione in normotensive and hypertensive pregnancy. Steroids 1987, in press
  • Hähnel M. E., Martin J. D., Hähnel R. Plasma 19‐Hydroxyandrostenedione in hypertensive diseases of pregnancy: Influence of delivery and betamethasone, (Abstract). Clin. Biochem. Revs. 1985; 6: 104
  • Buster J. E., Chang R. J., Preston D. L., et al. Interrelationships of circulating maternal steroid concentrations in third trimester pregnancies. II.C1 and C19 steroids: Estradiol, estriol, dehydroepiandrosterone. dehyroepiandrosterone sulfate, Δ‐androstenediol, Δ4‐androstenedione, testosterone and dihydrotestosterone. J. Clin. Endocrinol. Metab. 1979; 48: 139
  • Rivarola M. A., Forest M. G., Migeon C. J. Testosterone, androstenedione and dehydroepiandrostenedione in plasma during pregnancy and at delivery: Concentration and protein binding. J. Clin. Endocrinol. Metab. 1968; 28: 34
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  • Lehmann W. D., Lauritzen Ch., Schumann R. In vitro conversion of (4–14C) dehydroepiandrosterone and androstenedione to oestrogens by the microsomes of placentas from normal, toxaemic, diabetic and postmature pregnancies. Acta Endocr. Copenh. 1973; 73: 771
  • Mancuso S., Dellacqua S., Eriksson G., Wiquist N., Diczfalusy E. Aromatization of androstenedione and testosterone by the human fetus. Steroids 1965; 5: 183
  • Sekihara H. 19‐Hydroxyandrostenedione: Evidence for a new class of sodium‐retaining and hypertensinogenic steroids. Endocrinology 1983; 113: 1141
  • Sekihara S., Torii R., Osawa Y., Takaku F. Angiotensin II induces the release of 19‐hydroxyandrostenedione in man. J. Clin. Endocrinol. Metab. 1985; 61: 291
  • Gomez‐Sanchez E. P., Gomez‐Sanchez C. E. A re‐evaluation of the mineralocorticoid and hypertensinogenic potential of 19‐hydroxyandrostenedione. J. Clin. Endocrinol. 1986; 118: 2582
  • Sekihara H., Yonemitsu K., Takaku F. Enhancement of the hypertensiongenic action of 19‐hydroxyandrostenedione by aromatase inhibitor Δ‐testolactone. J. Clin. Endocrinol. Metab. 1987; 121: 1931
  • Adam W. R., Funder J. W., Mercer J., Ulick S. Amplification of the Action of Aldosterone by 5α‐Dihydrocortisol. Endocrinology 1978; 103: 465
  • Sekihara H. 19‐Hydroxyandrostenedione: A potent hypertensinogenic steroid in man. J. Steroid. Biochem. 1983; 19: 353
  • Rosing U., Carlstrom K. Serum levels of unconjugated and total oestrogens and dehydroepiandrostexone, progesterone and urinary oestriol excretion in pre‐eclampsia. Gynaecol. Obstet. Invest. 1984; 18: 199
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