Pathogenesis of Pregnancy-Induced Hypertensive Disorders A Review of Experimental Animal Models

References

• Abitbol M. M., Gallo G. R., Pirani C. L. “Production of experimental toxemia in the pregnant rabbit”. Am.J.Obstet.Gynecol. 1976; 124: 460
   PubMed Web of Science ®Google Scholar
• Abitbol M. M., Driscoll S. G., Ober W. B. “Placental lesions in experimental toxemia in the rabbit”. Am.J.Obstet.Gynecol. 1976; 125: 942
   PubMed Web of Science ®Google Scholar
• Abitbol M. M., Pirani C. L., Ober W. B. “Production of experimental toxemia in the pregnant dog”. Obstet.Gynecol. 1976; 48: 537
   PubMedGoogle Scholar
• Abitbol M. M., Ober W. B., Gallo G. R. “Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone”. Am.J.Pathol. 1977; 86: 573
   PubMedGoogle Scholar
• Abitbol M. M. “Hemodynamic studies in experimental toxemia of the dog”. Obstet.Gynecol. 1977; 50: 293
   PubMed Web of Science ®Google Scholar
• Abitbol M. M. “A simplified technique to produce toxemia in the pregnant dog”. Am.J.Obstet.Gynecol. 1981; 139: 526
   PubMed Web of Science ®Google Scholar
• Assali N. S., Longon L. U., Holm L. W. “Toxemia-like syndromes in animals Spontaneous and experimental”. Obstet.Gynecol.Surv. 1960; 15: 151
   PubMedGoogle Scholar
• Beer A. E. “Immunogenetic determinants of the size of the fetoplacental unit and their modus operandi”. Europ.J.Obstet.Gynec.Reprod.Biol. 1975; 5/1-2(135)
   Google Scholar
• Beer A. E., Scott J. R., Billingham R. E. “Histo-incompatibility and maternal immunological status as determinants of fetoplacental weight and litter size in rodents”. J.Exper.Med. 1975; 142: 180
   PubMed Web of Science ®Google Scholar
• Berger M., Cavanagh D. “Toxemia of pregnancy The hypertensive effect of acute experimental placental ischemia”. Am.J.Obstet.Gynec. 1963; 87: 293
   PubMedGoogle Scholar
• Berger M., Boucek R. J. “Irreversible uterine and renal changes induced by placental ischemia (rabbit)”. Am.J.Obstet.Gynec. 1964; 89: 230
   PubMedGoogle Scholar
• Berssenbrugge A. D., Goodfriend T. L., Ball D. L. “The effect of pregnancy on the angiotensin II pressor response in the rabbit”. Am.J.Obstet. Gynec. 1980; 136: 762
   PubMed Web of Science ®Google Scholar
• Billington W. D. “Influence of immunological dissimilarity of mother and foetus on size of placenta in mice”. Nature 1964; 202: 317
   PubMedGoogle Scholar
• van Bouwdljk Bastiaanse M. A., Mastboom J. L. “Ischaemia of the gravid uterus as a probable factor In the causation of toxaemia”. Toxaemias of Pregnancy Human and Veterinary, J. Hammond, F. J. Browne, G. E.W. Wolstenholm, Philadelphia, Blakiston 1950; 182
   Google Scholar
• Bregulla K., Hennig F. “Untersuchungen zum Problem des Schwangerschafts-hochdrucks als Folge einer utero-plazentaren Ischaemie”. Arch.Gynäk. 1977; 222: 345
   PubMedGoogle Scholar
• Cavanagh D., Rao P. S., Tung K. “Toxemia of pregnancy The development of an experimental model in the primate”. Obstet.Gynecol. 1972; 39: 637
   Google Scholar
• Cavanagh D., Rao P. S., Tung K. S.K. “Eclamptogenic toxemia: The development of an experimental model in the subhuman primate”. Am.J.Obstet. Gynecol. 1974; 120: 183
   PubMedGoogle Scholar
• Cavanagh D., Rao P. S., Tsai C. C. “Experimental toxemia in the pregnant primate”. Am.J.Obstet.Gynecol. 1977; 128: 75
   PubMed Web of Science ®Google Scholar
• Cavanagh D., Rao P. S., Knuppel R. A. “Pregnancy-induced hypertension: development of a model in the pregnant primate (papio anubis)”. Am.J.Obstet.Gynecol. 1985; 151: 987
   PubMed Web of Science ®Google Scholar
• Chesley L. C. “Hypertensive disorders in pregnancy”. Appleton Century Crofts, New York 1978
   Google Scholar
• Chez R. A. “Nonhuman primate models of toxemia of pregnancy”. Hypertension in Pregnancy, M. D. Lindheimer, A. I. Katz, F. P. Zuspan. Wiley & Sons, New York 1976; 421
   Google Scholar
• Church J. P., Reeves V. B., Schoene M. W. “Effects of essential fatty acid deficiency on blood pressure in the spontaneously hypertensive rat”. Fed.Proc. 1977; 36: 1159
   Google Scholar
• Clark K. E., Mills E. G., Stys S. J. “Effects of vasoactive polypeptides on the uterine vasculature”. Am.J.Obstet.Gynecol. 1981; 139: 182
   PubMedGoogle Scholar
• Clark K. E., Austin J. E., Seeds A. E. “Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep”. Am.J.Obstet. Gynecol. 1982; 142: 261
   PubMedGoogle Scholar
• Craig J. M. “Models for obstetrical and gynecological disease”. Fed.Proc. 1969; 28: 206
   PubMedGoogle Scholar
• Croy B. A., Rossant J., Clark D. A. “Histological and immunological studies of post implantation death of Mus caroli embryos in the Mus musculus uterus”. J.Reprod.Immunol. 1982; 4: 277
   PubMedGoogle Scholar
• Dawson W. D., Reuning S. C., Finlay M. F. “Immunological factors In Peromyscus Speciation”. J.Experim.Zool. 1982; 224: 1
   PubMedGoogle Scholar
• Donker A. J.M., Min I., Venuto R. C. “The conscious instrumented rabbit: a model for the study of mechanisms of blood pressure regulation during pregnancy”. Hypertension 1983; 5: 514
   PubMed Web of Science ®Google Scholar
• Douglas B. H., Langford H. G. “Toxemia of pregnancy: Production of lesions in the absence of signs”. Am.J.Obstet.Gynecol. 1966; 95: 534
   PubMedGoogle Scholar
• Franke H., Oswald B., Goetze E. “Elektronenoptische Untersuchungen über die Reaktion der Trophoblastzellen der Ratten-plazenta nach Einwirkung von Kaninchennormal- und Kaninchen-anti-rattenplazentaserum”. Acta Biol.Med.Germ. 1971; 26: 371
   PubMedGoogle Scholar
• Head J. R., Smith W. G. “Pregnancy-induced hyporesponsiveness to paternal alloantigens. II Factors affecting altered expressions of immunity in parous rats”. Transplantation 1982; 34: 258
   PubMedGoogle Scholar
• Hodari A. A. “Chronic uterine ischemia and reversible experimental “toxemia of pregnancy”. Am.J.Obstet.Gynecol. 1967; 97: 597
   PubMed Web of Science ®Google Scholar
• Hollister M. C., Reid D. L., Phennerton T. M. “Dose-response curves of the uterine and placental vascular beds to prostaglandin 12”. Am.J.Obstet.Gynaecol. 1988; 159: 1372
   PubMedGoogle Scholar
• Hutten J. W.M., Kuijpers J. C., van Velzen D., Wallenburg H. C.S. “Pregnancy-induced hypertension in crossbred rats. I. Maternal and fetal outcome of pregnancy”. Int.J.Feto-Maternal Med. 1988; 1: 51
   Google Scholar
• Hutten J. W.M., Kuijpers J. C., van Velzen D., Wallenburg H. C.S. “Pregnancy-induced hypertension in crossbred rats. II. Quantification of histologic expression in placenta and fetal liver”. Int.J.Feto-Maternal Med. 1988; 2: 9
   Google Scholar
• Karpen C. W., Merola A. J., Trewijn R. W., Cornwell D. G., Panganamala R. V. “Modulation of platelet thromboxane A2 and arterial prostacyclin by dietary vitamin E”. Prostaglandins 1981; 22: 651
   PubMed Web of Science ®Google Scholar
• Katz M., Creasy R. K. “Uterine blood flow distribution after indomethacin infusion in the pregnant rabbit”. Am.J.Obstet.Gynecol. 1981; 140: 430
   PubMed Web of Science ®Google Scholar
• Keith J. C., Thatcher C. D., Schaub R. G. “Benificial effects of U-63, 557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension”. Am.J.Obstet.Gynec. 1987; 157: 199
   PubMed Web of Science ®Google Scholar
• Keith J. C., Miller K., Eggleston M. K., Kutruff J., Howerton T., Konczal C., McDaniels C. “Effects of thromboxane synthetase inhibition on maternal-fetal homeostasis in gravid ewes with ovine pregnancy-induced hypertension”. Am.J.Obstet.Gynecol. 1989; 161: 1305
   PubMed Web of Science ®Google Scholar
• Kumar D. “Chronic placental ischemia in relation to toxemias of pregnancy”. Am.J.Obstet.Gynecol 1962; 84: 1323
   Web of Science ®Google Scholar
• Langford H. G., Douglas B. H., Arhelger R. B. “A model of pre-eclampsia 1. Blood pressure changes produced by anti-placenta serum”. Johns Hopkins Med.J. 1967; 120: 213
   PubMedGoogle Scholar
• Leffler C. W., Hessler J. R., Green R. S., Fletcher A. M. “Effects of sodium chloride on pregnant sheep with reduced uteroplacental perfusion pressure”. Hypertension 1986; 8: 62
   PubMed Web of Science ®Google Scholar
• Losonczy G., Todd H., Palmer D. C. “Prostaglandins, norepinephrine, angiotensin II and blood pressure changes induced by uteroplacental ischemia in rabbits”. Clin.Exper.Hyper-Hyper in Pregn 1986; B5(271)
   Google Scholar
• MacGillivray I. “Pre-eclampsia. The hypertensive disease of pregnancy”. W.B.Saunders Co. Ltd., London, Philadelphia, Toronto 1983
   Google Scholar
• Mahoney D., Croft K., Beilin L. J. “Influence of dietary polyunsaturated fatty acids on renal and aortic prostaglandin synthesis in 1 kidney 1 clip Goldblatt hypertensive rats”. Prostaglandins 1983; 26: 479
   PubMedGoogle Scholar
• McKay D. G., Goldenberg V. E. “Pathogenesis of anatomic changes in experimental toxemia of pregnancy”. Obstet. Gynecol. 1963; 21: 651
   Google Scholar
• McKay D. G., Goldenberg V. E., Kaunitz H. “Experimental eclampsia An electron microscopic study and review”. Arch. Path. 1967; 84: 557
   PubMedGoogle Scholar
• Milgrom F., Comini-Andrada E., Chandhry A. P. “Fetal and neonatal fatality in rat hybrids from mothers stimulated with paternal skin”. Transpl.Proc. IX 1977; 2: 1409
   Google Scholar
• Misenhimer H. R., Ramsey E. M., Martin C. B. “Chronically impaired uterine artery blood flow”. Obstet. Gynecol. 1970; 36: 415
   PubMed Web of Science ®Google Scholar
• Moisey D. M., Tulenko T. “Increased sensitivity to angiotensin in uterine arteries from pregnant rabbits”. Am.J.Physiol 1983; 244, Heart Circ.Physiol. 13), H335
   PubMedGoogle Scholar
• Moncada S., Vane J. R. “Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin”. Pharmacol.Rev. 1979; 30: 293
   Web of Science ®Google Scholar
• Ogden E., Hildebrand G. J., Page E. W. “Rise of blood pressure during ischemia of the gravid uterus”. Proc.Soc.Exp.Biol.Med. 1940; 43: 49
   Google Scholar
• Okuda T., Grollman A. “Renal lesions in rats following injection of placental extracts”. Arch.Path. 1966; 82: 246
   PubMedGoogle Scholar
• Okuma M., Takayama H., Uchino H. “Generation of prostacyclin-like substance and lipid peroxidation in vitamin-E deficient rats”. Prostaglandins 1980; 19: 527
   PubMed Web of Science ®Google Scholar
• Paller M. S. “Mechanism of decreased pressor responsiveness to ANG II, NE, and vasopressin in pregnant rats”. Am.J.Physiol 1984; 247, (Heart Circ.Physiol 16), H100
   PubMedGoogle Scholar
• Palm J. “Maternal-fetal histoincompatibility in rats: an escape from adversity”. Cancer Res. 1974; 34: 2061
   PubMedGoogle Scholar
• Palmer A. E., London W. T., Sly D. L., Rice J. M. “Spontaneous preeclamptic toxemia of pregnancy in the Patas monkey (Erythrocebus patas)”. Lab.Anim.Sci. 1979; 29: 102
   PubMedGoogle Scholar
• Parisi V. M., Rankin J. H.G. “The effect of prostacyclin on angiotensin II-induced placental vasoconstriction”. Am.J.Obstet.Gynecol. 1985; 151: 444
   PubMedGoogle Scholar
• Parisi V. M., Walsh S. W. “Fetoplacental vascular responses to prostacyclin after thromboxane- induced vasoconstriction”. Am.J.obstet.Gynecol. 1989; 160: 502
   PubMedGoogle Scholar
• Rankin J. H.G., Bersenbrugge A., Anderson D. “Ovine placental vascular responses to indomethacin”. Am.J.Physiol 1979; 236, (Heart Circ.Physiol. 5), H61
   Google Scholar
• Rankin J. H.G., Phernetton T. M., Anderson D. F. “Effect of prostaglandin 12 on ovine placental vasculature”. J.Dev. Physiol. 1979; 1: 151
   PubMedGoogle Scholar
• Resnik R., Brink G. W. “Uterine vascular response to prostacyclin in non pregnant sheep”. Am.J.Obstet.Gynecol. 1980; 137: 267
   PubMedGoogle Scholar
• Robertson W. B., Khong T. Y., Brosens I. “The placental bed biopsy: review from three European centers”. Am.J.Obstet. Gynecol. 1986; 155: 401
   PubMed Web of Science ®Google Scholar
• Scherhag R., Kramer H. J., Duusing R. “Dietary administration of eicosapentanoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in rat”. Prostaglandins 1982; 23: 369
   PubMedGoogle Scholar
• Seegal B. C., Loeb E. N. “The production of chronic glomerulo-nephritis in rats by the injection of rabbit anti-rat-placenta serum”. J.Exp.Med. 1946; 84: 211
   Web of Science ®Google Scholar
• Smith R. W., Taniguchi A. G. “Angiotensin sentivity in experimental uteroplacental ischemia”. Am.J.Obstet.Gynecol. 1966; 94: 303
   PubMedGoogle Scholar
• Spitz B., Deckmyn H., Pijnenborg R., Van Assche F. A., Vermylen J. “Prostacyclin (PGI2) production by aortic rings and mesometrial triangles in pregnant rats, fed an anti-vitamin E stress diet” (Abstract). Thromb.Haemost. 1983; 50: 240
   Google Scholar
• Spitz B., Deckmyn H., Van Bree R., Pijnenborg R., Vermylen J., Van Assche F. A. “Influence of a vitamin-E deficient diet on prostacyclin production by mesometrial triangles and aortic rings from non diabetic and diabetic pregnant rats”. Am.J.Obstet.Gynecol. 1985; 151: 116
   PubMedGoogle Scholar
• Srivastava K. C. “Vitamin E exerts antiaggregating effects without inhibiting the enzymes of the arachidonic acid cascade in platelets”. Prostagl.Leukotr.Med. 1986; 21: 177
   PubMedGoogle Scholar
• Stamler W. F. “Fatal eclamptic disease of pregnant rats fed anti vitamin E stress diet”. Am.J.Pathol. 1959; 35: 1207
   PubMedGoogle Scholar
• Ten Hoor F., van de Graaf H. M. “The influence of a linoleic acid-rich diet and of acetyl salicylic acid on NaCl induced hypertension, Na+- and H2O- balance and urinary prostaglandin excretion in rats”. Acta Biol.Med.Germ. 1978; 37: 875
   PubMedGoogle Scholar
• Thatcher C. D., Keith J. C. “Pregnancy-induced hypertension: development of a model in the pregnant sheep”. Am.J.Obstet.Gynecol. 1986; 155: 201
   PubMed Web of Science ®Google Scholar
• Triebe G., Block H. U., Förster W. “On the blood pressure response of salt- loaded rats under different content of linoleic acid in the food”. Acta Biol.Med.Germ. 1976; 35: 1223
   PubMedGoogle Scholar
• Valentovic M. A., Gairola C., Lubawy W. C. “Lung, aorta, and platelet metabolism of 14C-arachidonic acid in vitamin E deficient rats”. Prostaglandins 1982; 24: 215
   PubMedGoogle Scholar
• Venuto R., Min I., Barone P. “Blood pressure control in pregnant rabbits: norepinephrine and prostaglandin interactions”. Am.J.Physiol 1984; 247, (Regulatory Integrative Comp.Physiol. 16), R 786
   PubMedGoogle Scholar
• Wallenburg H. C.S. “Prevention of preeclampsia”. J.Clin.Exp.Hyp. 1988; B7(121)
   Google Scholar
• Wardle E. N., Wright N. A. “Role of fibrin in a model of pregnancy toxemia in the rabbit”. Am.J.Obstet.Gynecol. 1973; 115: 17
   PubMedGoogle Scholar
• Wegmann T. G. “The presence of class I MHC antigens at the maternal-fetal interface and hypotheses concerning the survival of the murine fetal allograft”. J.Reprod.Immun. 1981; 3: 267
   PubMedGoogle Scholar
• Weiner C. P., Hdez M., Chestnut D. H. “The interaction between serotonin and angiotensin II in the chronically instrumented guinea pig and its alteration by indomethacin”. Am.J.Obstet.Gynecol. 1987; 156: 869
   PubMed Web of Science ®Google Scholar
• Weiner C. P., Hdez M., Chestnut D. H. “Effect of exogenous prostacyclin on central and uterine hemodynamics in the cronically instrumented pregnant guinea pig before and after indomethacin administration”. Am.J.Obstet.Gynecol 1989; 160(489)
   Google Scholar
• Woods L. L. “Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressure”. Am. J. Physiol. 1989; 257: 1558
   PubMed Web of Science ®Google Scholar
• Woods L. L., Brooks V. L. “Role of the renin-angiotensin system in hypertension during reduced uteroplacental perfusion pressure”. Am.J.Physiol. 1989; 257: 204
   PubMed Web of Science ®Google Scholar