Advanced search
Publication Cover
Hypertension in Pregnancy Volume 12, 1993 - Issue 1
Submit an article Journal homepage
9
Views
15
CrossRef citations to date
0
Altmetric
Original Article

Increases in Urinary Inhibitor Activity and Excretion of an Inhibitor of Crystalluria in Pregnancy: A Defense Against the Hypercalciuria of Normal Gestation

John M. Davison Department of Obstetrics and Gynaecology, The University of Newcastle, Newcastle upon Tyne, UK
,
Yasushi Nakagawa Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL; Nephrology Program, Department of Medicine, The University of Chicago, Chicago, IL
,
Fredric L. Coe Nephrology Program, Department of Medicine, The University of Chicago, Chicago, IL
&
Marshall D. Lindheimer Nephrology Program, Department of Medicine, The University of Chicago, Chicago, IL; Department of Obstetrics and Gynecology, The University of Chicago, Chicago, IL
Pages 25-35 | Published online: 07 Jul 2009

References

  • Belizan JM, Villar J, Repke J. The relationship between calcium intake and pregnancy-induced hypertension: up-to-date evidence. Am J Obstet Gynecol. 1988; 158: 898–902
  • MaCarron DA. Calcium and hypertension. Kidney Int. 1989; 35: 717–736
  • Taufield PA, Ales KL, Resnick LM, Druzin ML, Gertue JM, Laragh J. Hypocalciuria in preeclampsia. N Eng J Med. 1987; 316: 715–718
  • Rodriguez MH, Masaki DI, Mestman J, Kumar D, Rude R. Calcium/creatinine ratio and microalbuminuria in the prediction of preeclampsia. Am J Obstet Gynecol. 1988; 159: 1452–1456
  • Covi G, Corsato M, Paluani F, Marcolongo A, Minuz P, Lechi A. Reduced urinary excretion of calcium in pregnancy-induced hypertension. Clin Exp Hypertens. 1990; B9: 151–167
  • Hutchesson ACJ, Macintosh MC, Duncan SLB, Forrest ARW. Hypocalciuria and hypertension in pregnancy: a prospective study. Clin Exp Hypertens. 1990; B9: 115–134
  • Sanchez-Ramoz L, Sandroni S, Andres FJ, Kaunitz AM. Calcium excretion in preeclampsia. Obstet Gynecol. 1991; 77: 510–513
  • Belizan JM, Villar J, Zalazar A, Rojas L, Chan D, Graeme FB. Preliminary evidence of the effect of calcium supplementation on blood pressure in normal pregnant women. Am J Obstet Gynecol. 1983; 146: 175–180
  • Villar J, Repke J, Belizan JM, Pareja G. Calcium supplementation reduces blood pressure during pregnancy: results of a randomized controlled clinical trial. Obstet Gynecol. 1987; 70: 317–322
  • Lopez-Jaramillo P, Narvaez M, Weigel RM, Yepez R. Calcium supplementation reduced the risk of pregnancy-induced hypertension in an Andes population. Br J Obstet Gynaecol. 1989; 96: 648–655
  • Villar J, Repke J. Calcium supplementation during pregnancy may reduce preterm delivery in a high risk population. Am J Obstet Gynecol. 1990; 163: 1124–1131
  • Belizan JM, Villar J, Gonzales L, Campodonico L, Bergel E. Calcium supplementation to prevent hypertensive disorders of pregnancy. N Eng J Med. 1991; 325: 1399–1405
  • Maikranz P, Holley JL, Parks JH, Lindheimer MD, Nakagawa Y, Coe FL. Gestational hypercalciuria causes pathological urine calcium oxalate supersaturation. Kidney Int. 1989; 36: 108–113
  • Maikranz P, Coe FL, Parks JH, Lindheimer MD. Nephrolithiasis and gestation. Clin Obstet Gynaecol. (Bailliere) 1987; 1: 909–919
  • Nakagawa Y, Abram V, Kedzy FJ, Kaiser ET, Coe FL. Purification and characterization of the principal inhibitor of calcium oxalate monohydrate crystal growth in human urine. J Biol Chem. 1983; 258: 12594–12600
  • Nakagawa Y, Margolis HC, Yokoyama S, Kedzy FJ, Kaiser ET, Coe FL. Purification and characterization of the principal inhibitor from human kidney tissue culture medium. J Biol Chem. 1981; 256: 3936–3944
  • Nakagawa Y, Sirivongs D, Novy MB, Netzer MF, Michaels E, Vogelzang NJ, et al. Nephrocalcin: biosynthesis by human renal carcinoma cells in vitro and in vivo. Cancer Res. 1992; 52: 1573–1579
  • Towbin H, Straehlin T, Gordon J. Electrophoretic transfer of proteins from polyacrilimide gels to nitrocellulose sheets: procedure and some applications. Proc Nat Acad Sci. 1979; 76: 4350–4354
  • Nakagawa Y, Ahmed M-A, Hall SL, Deganello S, Coe FL. Isolation from human calcium oxalate renal stones of nephrocalcin, a glycoprotein inhibitor of calcium oxalate crystal growth. J Clin Invest. 1987; 79: 1782–1787
  • Matthews J, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. Br Med J. 1990; 300: 230–235
  • Howarth AT, Morgan D, Payne R. Urinary excretion of calcium in late pregnancy and its relation to creatinine clearance. Am J Obstet Gynecol. 1977; 129: 499–503
  • Coe FL, Parks JH, Lindheimer MD. Nephrolithiasis during pregnancy. N Eng J Med. 1978; 298: 324–326
  • Nakagawa Y, Abram V, Parks JH, Lau S-H, Kawooya JK, Coe FL. Urine glycoprotein crystal growth inhibitors: evidence for a molecular abnormality in calcium oxalate nephrolithiasis. J Clin Invest. 1985; 76: 1455–1462
  • Lindheimer MD, Katz AI. The kidney and hypertension in pregnancy. The Kidney.4th ed., BM Brenner, FC Rector, Jr. WB Saunders, Philadelphia 1991; 1551–1595
  • Nakagawa Y, Sirivongs D, Maikranz P, Lindheimer MD, Coe FC. Excretion of Tamm Horsfall glycoprotein (THP) during pregnancy: a defence against nephrolithiasis. Kidney Int. 1988; 33: 203, (abstr)
  • Rath W, Nebelhut T, Kuhn W. Urinary excretion of Tamm Horsfall protein and N-acetyl-β-glucosamidase in normal and hypertensive pregnancies. Clin Exp Hypertens. 1991; B10: 84, (abstr)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.