13
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Magnesium Sulfate Reduces Seizures Induced by Central Administration of the Excitatory Amino Acid N-Methyl-D-Aspartate in Rats

, , , &
Pages 235-244 | Published online: 07 Jul 2009

References

  • Dingledine R, McBain C J, McNamara J O. Excitatory amino acid receptors in epilepsy. Trends Pharmacol Sci 1990; 11: 334–8
  • Mayer L M, Westbrook G L, Guthrie P B. Voltage‐dependent block by Mg2+ of NMDA responses in spinal cord neurons. Nature 1984; 309: 261–3
  • Pritchard J A, Cunningham G, Pritchard S A. The Parkland Memorial Hospital protocol for treatment of eclampsia: evaluation of 245 cases. Am J Obstet Gynecol 1984; 148: 951–63
  • Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates2nd ed. Academic Press, New York 1986
  • Cotton D B, Janusz C A, Berman R F. Anticonvulsant effects of magnesium sulfate on hippocampal seizures: therapeutic implications in preeclampsia‐eclampsia. Am J Obstet Gynecol 1992; 166: 1127–36
  • Hallak M, Berman R F, Irtenkauf S M, Evans M I, Cotton D B. Peripheral magnesium sulfate enters the brain and increases the threshold for hippocampal seizures in rats. Am J Obstet Gynecol 1992; 167: 1605–10
  • Cotton D B, Hallak M, Janusz C, Irtenkauf S M, Berman R F. Central anticonvulsant effects of magnesium sulfate on NMDA‐induced seizures. Am J Obstet Gynecol 1993; 168: 974–8
  • Sibai B M, Spinnato J A, Watson D L, Lewis J A, Anderson G D. Effect of magnesium sulfate on electroencephalographic findings in preeclampsia‐eclampsia. Obstet Gynecol 1984; 64: 261–6
  • Borges L F, Gucer G. Effect of magnesium on epileptic foci. Epilepsia 1978; 19: 81–91
  • Katz A, Kerem D, Sherman D. Magnesium sulfate suppresses electroencephalographic manifestations of CNS oxygen toxicity. Undersea Biomed Res 1990; 28: 658–66
  • McDonald J W, Silverstein F S, Johnston M V. Magnesium reduces A'‐methyl‐D‐aspar‐tate (NMDA)‐mediated brain injury in perinatal rats. Neurosci Lett 1990; 109: 234–8
  • Dudel J, Parnas I, Parnas H. Neurotransmitter release and its facilitation in crayfish. III. amplitude of the facilitation and inhibition of entry of calcium into the terminal by magnesium. Pflugers Arch 1982; 393: 237–42
  • McLaughlin S G A, Szabo G, Eisenman G. Divalent ions and the surface potential of charged phospholipid membranes. J Gen Physiol 1971; 58: 667–87
  • Jones R S G, Heinemann U. Amino acid‐mediated synaptic transmission in temporal lobe structures in vitro, implications for the generation and spread of epileptic activity. Excitatory Amino Acids and Synaptic Function, H Wheal, A Thompson. Academic Press, San Diego 1991; 265–85
  • Chapman A G, Meldrum B S. Excitatory amino acid antagonists and epilepsy. Bio‐chem Soc Trans 1993; 21: 106–10
  • De Sarro G, De Sarro A. Anticonvulsant activity of competitive antagonists of NMDA receptor in genetically epilepsy‐prone rats. Eur J Pharmacol 1992; 215: 221–29
  • Morimoto K, Katayama K, Inoue K, Sato K. Effects of competitive and noncompetitive NMDA receptor antagonists on kindling and LTP. Pharmacol Biochem Behav 1991; 40: 893–9
  • Hallak M, Berman R F, Irtenkauf S M, Janusz C A, Cotton D B. Magnesium sulfate treatment decreases N,‐methyl‐D‐aspartate receptor binding in the rat brain: an autoradiographic study. J Soc Gynecol Invest 1994; 1: 25–30
  • Choi D W. Glutamate neurotoxicity and disease of the nervous system. Neuron 1988; 1: 623–34
  • Monaghan D T, Cotman C W. Distribution of N,‐methyl‐D‐aspartate‐sensitive L‐pH]glutamate‐binding sites in rat brain. J Neurosci 1985; 5: 2909–19
  • Dietrich W D, Malley M, Alonso O, Globus M Y.‐T, Busto R. Intraventricular infusion of N,‐methyl‐D‐aspartate 2. acute neuronal consequences. Acta Neuropathol 1992; 84: 630–7

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.