10
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Kinetic Analysis of the Reaction of Human Renin with Human High and Low Molecular Weight Angiotensinogen

&
Pages 327-338 | Published online: 07 Jul 2009

References

  • Bunnemann B, Fuxe K, Bjelke B, Ganten D. The brain renin‐angiotensin system and its possible involvement in volume transmission. Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission, K Fuxe, L F Agnati. Raven Press, New York 1991; 131–58
  • Taddei S, Salvetti A. Vascular tissue renin‐angiotensin system in hypertensive humans. J Hypertens 1992; 10: S165–72
  • Mulrow P J. Adrenal renin: regulation and function. Front Neuroendocrinol 1992; 13: 47–60
  • Inagami T, Mizuno K, Kawamura M, Okamura T, Clemens D L, Higashimori K. Localization of components of the renin‐angiotensin system within the kidney and sustained release of angiotensins from isolated and perfused kidney. Tohoku J Exp Med 1992; 166: 17–26
  • Shaw K J, Do Y S, Kjos S, Anderson P W, Shinagawa T, Dubeau L, Hsueh W A. Human decidua is a major source of renin. J Clin Invest 1989; 83: 2085–92
  • Poisner A M, Wood G W, Poisner R, Inagami T. Renin and inactive renin in human amnion at term pregnancy. Proc Soc Exp Biol Med 1982; 169: 4–6
  • Lenz T, Sealey J E, Tewksbury D A. Regional distribution of the angiotensinogens in human placentas. Placenta 1993; 14: 695–9
  • Tewksbury D A, Tryon E S, Burrill R E, Dart R A. High molecular weight angiotensinogen: a pregnancy associated protein. Clin Chim Acta 1986; 158: 7–12
  • Tewksbury D A, Dart R A. High molecular weight angiotensinogen levels in hypertensive pregnant women. Hypertension 1982; 4: 729–34
  • Tewksbury D A, Burrill R E, Tryon E S, Dart R A. Study on high molecular weight angiotensinogen. Placental and Endometrial Proteins: Basic and Clinical Aspects. VSP, Utrecht 1988; 651–4
  • Tewksbury D A. Angiotensinogen. Fed Proc 1983; 42: 2724–8
  • Tewksbury D A, Dart R A, Travis J. The amino terminal amino acid sequence of human angiotensinogen. Biochem Biophys Res Commun 1981; 99: 1311–5
  • Kageyama R, Ohkubo H, Nakanishi S. Primary structure of human preangioten‐sinogen deduced from the cloned cDNA sequence. Biochemistry 1984; 23: 3603–9
  • Gaillard I, Clauser E, Corvol P. Structure of human angiotensinogen gene. DNA 1989; 8: 87–99
  • Tewksbury D A, Tryon E S. Immunochemical comparison of high molecular weight angiotensinogen from amniotic fluid, plasma of men and plasma of pregnant women. Am J Hypertens 1989; 2: 411–3
  • Tewksbury D A. Angiotensinogen: biochemistiry and molecular biology. Hypertension: Pathophysiology. Diagnosis and Management, J H Laragh, B M Brenner. Raven Press, New York 1990; 1197–216
  • Rosenthal J, Wolff H P, Weber P, Dahlheim H. Enzyme kinetic studies on human renin and its purified homologous substrate. Am J Physiol 1971; 221: 1292–6
  • Haas E, Goldblatt H. Kinetic constants of the human renin and human angiotensinogen reaction. Circ Res 1967; 20: 45–55
  • Gould A B, Green D. Kinetics of the human renin and human substrate reaction. Cardiovasc Res 1971; 5: 86–9
  • Schioler V, Damkjaer Nielsen M, Kappelgaard A M, Giese J. Partial purification of human renin substrate. Eur J Clin Invest 1976; 6: 229–40
  • Printz M P, Printz J M, Dworschack R T. Human angiotensinogen. Purification, partial characterization and a comparison with animal prohormones. J Biol Chem 1977; 252: 1654–62
  • Hsueh W A, Carlson E J, Dzau V J. Characterization of inactive renin from human kidney and plasma, evidence of a renal source of circulating inactive renin. J Clin Invest 1983; 71: 506–17
  • Slater E E, Strout H V J, Jr. Pure human renin, identification and characterization of two major molecular weight forms. J Biol Chem 1981; 256: 8164–71
  • Haas E, Goldblatt H, Gipson E C, Lewis L. Extraction, purification, and assay of human renin free angiotensinase. Circ Res 1966; 19: 739–49
  • Eisenthal R, Cornish‐Bowden A. The direct linear plot: a new graphical procedure for estimating enzyme kinetic parameters. Biochem J 1974; 139: 715–20
  • Cornish‐Bowden A. Fundamentals of Enzyme Kinetics. Butterworths, London 1979; 26–7
  • Mycek M J. Cathepsins. Methods Enzymol 1970; 19: 285–315
  • Bradford M M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein‐dye binding. Anal Biochem 1976; 72: 248–54
  • Yokosawa H, Holladay L A, Inagami T, Haas E, Murakami K. Human renal renin: complete purification and characterization. J Biol Chem 1980; 255: 3498–502
  • Barrett A J, Starkey P M. The interaction of alpha‐2‐macroglobulin with proteinases: characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. Biochem J 1973; 133: 709–24
  • Pickens P T, Bumpus F M, Lloyd A M, Smeby R R, Page I H. Measurement of renin activity in human plasma. Circ Res 1965; 17: 438–48
  • Katz F H, Smith J A. Radioimmunoassay of angiotensin I: comparison of two renin activity methods and use for other measurements of the renin system. Clin Chem 1972; 18: 528–33
  • Sato Y, Hiwada K, Kokubu T. Physicochemical characteristics of human high molecular weight angiotensinogen. Life Sci 1985; 37: 371–7
  • Cornish‐Bowden A. Fundamentals of Enzyme Kinetics. London: Butterworths 1979; 85
  • Barrett J D, Eggena P, Hidaka H, Sambhi M P. In vitro inhibition of renin by human des‐angiotensin I renin substate. J Clin Endocrinol Metab 1979; 48: 96–100
  • Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C, Farrington P F, Ogasawara M, Suzumori K, Tomoda S, Berrebi S, Sasaki M, Corvol P, Lifton R P, Lalouel J ‐M. A molecular variant of angiotensinogen associated with preeclampsia. Nature Genetics 1993; 4: 59–61
  • Arngrimsson R, Purandare S, Connor M, Walker J J, Björnsson S, Soubrier F, Ko‐televtsev Y V, Geirsson R T, Björnsson H. Angiotensinogen: a candidate gene involved in preeclampsia [letter]. Nature Genetics 1993; 4: 114–5

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.