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Hypertension in Pregnancy Volume 14, 1995 - Issue 1
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Original Article

Low-Dose Aspirin in the Prevention of Hypertensive Disorders of Pregnancy in Relatively Low-Risk Nulliparous Women

N. J. Davies Liverpool Maternity Hospital, Oxford Street, Liverpool, L7 7BN, UK
,
M. R. Gazvani Liverpool Maternity Hospital, Oxford Street, Liverpool, L7 7BN, UK
,
R. G. Farquharson Liverpool Maternity Hospital, Oxford Street, Liverpool, L7 7BN, UK
&
S. A. Walkinshaw Liverpool Maternity Hospital, Oxford Street, Liverpool, L7 7BN, UK
Pages 49-55 | Published online: 07 Jul 2009

References

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  • Imperiale T F, Stollenwerk Petrulis A. A meta-analysis of low-dose aspirin for the prevention of pregnancy-induced hypertensive disease. JAMA 1991; 266: 260–4
  • Uzan S, Beaufils M, Breart G, Bazin B, Capitant C, Paris J. Prevention of fetal growth retardation with low-dose aspirin: findings of the EPREDA trial. Lancet 1991; 337: 1427–31
  • Italian Study of Aspirin in Pregnancy Low-dose aspirin in prevention and treatment of intrauterine growth retardation and pregnancy-induced hypertension. Lancet 1993; 341: 396–400
  • Murphy J F, O'Riordan J, Newcombe R G, Coles E C, Pearson J F. Relation of haemoglobin levels in the first and second trimesters to outcome of pregnancy. Lancet 1986; i: 992–4
  • O'Brien W F. Predicting Pre-eclampsia. Obstet Gynecol 1990; 75: 445–52
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  • Wallenburg H CS, Dekker G A, Makovitz J W, Rotmans P. Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive pri-migravidae. Lancet 1986; 1: 1–3
  • Beaufils M, Uzan S, Donsimoni R, Colau J C. Prevention of pre-eclampsia by early antiplatelet therapy. Lancet 1985; i: 840–2
  • Schiff E, Peleg E, Goldenberg M, Rosenthal T, Ruppin E, Tamarkin M, et al. The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of Thromboxane A2 to prostacylin in relatively high risk pregnancies. N Engl J Med 1989; 321: 351–6
  • Viinikka L, Hartikainen-Sorri A-L, Lumme R, Hiilesmaa V, Ylikorkala O. Low-dose aspirin in hypertensive pregnant women: effect on pregnancy outcome and prostacylin-thromboxane balance in mother and newborn. Br J Ob Gynaecol 1993; 100: 809–15
  • Sibai B M, Caritis S N, Thorn E, Klebanoff M, Mc Nellis D, Rocco L, et al. Prevention of Pre-eclampsia with low-dose aspirin in healthy, nulliparous pregnant women. N Engl J Med 1993; 329: 1213–8
  • Hauth J C, Goldenberg R L, Parker C R, Philips J B, Copper R L, DuBard M B, et al. Low-dose aspirin to prevent preeclampsia. Am J Obstet Gynecol 1993; 168: 1083–93

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