Effect of Treadmill Exercise and Ferula gummosa on Myocardial HSP72, Vascular Function, and Antioxidant Defenses in Spontaneously Hypertensive Rats

REFERENCES

• Park Y-H, Song M, Cho B-L, Lim J-Y, Song W, Kim S-H. The effects of an integrated health education and exercise program in community-dwelling older adults with hypertension: a randomized controlled trial. Patient Educ Couns 2011; 82:133–137.
   PubMed Web of Science ®Google Scholar
• Mahmoodi Seeyed AA, Reza G, Valiollah DR, Mehdi H. Individual and concomitant effects of cardioprotective programs on cardiac apelinergic system and oxidative state in L-NAME-Induced hypertension. Clin Exp Hypertens 2013; 35:20–27.
   PubMed Web of Science ®Google Scholar
• Cardoso Jr CG, Gomides RS, Queiroz ACC, Acute and chronic effects of aerobic and resistance exercise on ambulatory blood pressure. Clinics 2010; 65(3):317–325.
   PubMed Web of Science ®Google Scholar
• Husain K. Exercise conditioning attenuates the hypertensive effects of nitric oxide synthase inhibitor in rat. Mol Cell Biochem 2002; 231:129–137.
   PubMed Web of Science ®Google Scholar
• Morán M, Delgado J, González B, Manso R, Megías A. Responses of rat myocardial antioxidant defences and heat shock protein HSP72 induced by 12 and 24-week treadmill training. Acta Physiol Scand 2004; 180:157–166.
   PubMedGoogle Scholar
• Viswanatha Swamy AHM, Wangikar U, Koti BC, Thippeswamy AHM, Ronad PM, Manjula DV. Cardioprotective effect of ascorbic acid on doxorubicin-induced myocardial toxicity in rats. Indian J Pharmacol 2011; 43(5):507–511.
   PubMed Web of Science ®Google Scholar
• Förstermann U. Nitric oxide and oxidative stress in vascular disease. Pflugers Arch 2010; 459(6):923–939.
   PubMed Web of Science ®Google Scholar
• Förstermann U. Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies. Nat Clin Pract Cardiovasc Med 2008; 5(6):338–349.
   PubMedGoogle Scholar
• Cecen E, Dost T, Culhacı N, Karul A, Ergur B, Protective BM. Effects of silymarin against doxorubicin-induced toxicity. Asian Pacific J Cancer Prev 2011; 12:2697–2704.
   PubMed Web of Science ®Google Scholar
• Ascensao A, Magalhães J, Soares J, Endurance training attenuates doxorubicin-induced cardiac oxidative damage in mice. Int J Cardiol 2005; 100:451–460.
   PubMed Web of Science ®Google Scholar
• Fazel SF, Ebrahimzadeh MA, Nabavi SM, Eslami B. Antioxidant activity of flower, stem and leaf extracts of Ferula gummosa Boiss. Grasas Y Aceites 2010; 61(3):244–250.
   Web of Science ®Google Scholar
• Ghasemi K, Ghasemi Y, Ebrahimzadeh MA. Antioxidant activity, phenol and flavonoid contents of 13 citrus species peels and tissues. Pak J Pharm Sci 2009; 22(3):277–281.
   PubMed Web of Science ®Google Scholar
• Abedi D, Jalali M, Asghari G, Sadeghi N. Composition and antimicrobial activity of oleogumresin of Ferula gumosa Boiss. Essential oil using Alamar Blue™. Res Pharm Sci 2008; 3(1):41–45.
   Google Scholar
• Ghasemi Y, Faridi P, Mehregan I, Mohagheghzadeh A. Ferula gummosa fruits: an aromatic antimicrobial agent. Chem Nat Compd 2005; 41(3):311–314.
   Web of Science ®Google Scholar
• Zargari A, ed. Medicinal Plants, 2nd ed. Tehran: Tehran University Publication; 1991.
   Google Scholar
• Nadjafi F, Bannayan M, Tabrizi L, Rastgoo M. Seed germination and dormancy breaking techniques for Ferula gummosa and Teucrium polium. J Arid Environ 2006; 64:542–547.
   Web of Science ®Google Scholar
• Mandegary A, Sayyah M, Heidari MR. Antinociceptive and anti-inflammatory activity of the seed and root extracts of Ferula gummosa Boiss in mice and rats. Daru 2004; 12(2):58–62.
   Google Scholar
• Roshan VD, Assali M, Moghaddam AH, Hosseinzadeh M, Myers J. Exercise training and antioxidants: effects on rat heart tissue exposed to lead acetate. Int J Toxicol 2011; 30(2):190–196.
   PubMed Web of Science ®Google Scholar
• Aksu I, Topcu A, Camsari UM, Acikgoz O. Effect of acute and chronic exercise on oxidant–antioxidant equilibrium in rat hippocampus, prefrontal cortex and striatum. Neurosci Lett 2009; 452:281–285.
   PubMed Web of Science ®Google Scholar
• Wallace JP. Exercise in hypertension. A clinical review. Sports Med 2003; 33(8):585–598.
   PubMed Web of Science ®Google Scholar
• Lunz W, Capettini LS, Davel AP, L-NAME treatment enhances exercise-induced content of myocardial heat shock protein 72 (Hsp72) in rats. Cell Physiol Biochem 2011; 27(5):479–486.
   PubMed Web of Science ®Google Scholar
• Golbidi S, Laher I. Molecular mechanisms in exercise-induced cardioprotection. Cardiol Res Pract 2011; 2011:972807.
   PubMedGoogle Scholar
• Jafari A, Faizi MA, Askarian F, Pourrazi H. Effect of regular aerobic exercise with ozone exposure on peripheral leukocyte populations in Wistar male rats. J Res Med Sci 2009; 14(5):277–283.
   PubMed Web of Science ®Google Scholar
• Salo DC, Donovan CM, Davies KJ. HSP70 and other possible heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise. Free Radic Biol Med 1991; 11(3):239–246.
   PubMed Web of Science ®Google Scholar
• Dabidi Roshan V, Ranjbar S, Hosseinzadeh M, Myers J. Left ventricular oxidant and antioxidant markers induced by lifestyle modification in rats exposed to lead acetate. Eur J Sport Sci 2011:1–6. doi:10.1080/17461391.2011.573579.
   Google Scholar
• Schulz E, Gori T, Münzel T. Oxidative stress and endothelial dysfunction in hypertension. Hypertens Res 2011; 34(6):665–673.
   PubMed Web of Science ®Google Scholar
• Schulz E, Jansen T, Wenzel P, Daiber A, Münzel T. Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension. Antioxid Redox Signal 2008; 10(6):1115–1126.
   PubMed Web of Science ®Google Scholar
• Korzeniowska Kubacka I. Physical training as an effective way to protect the heart against ischaemia. Kardiol Pol 2011; 69(Suppl. 3):75–79.
   PubMedGoogle Scholar
• Powers SK, Quindry JC, Kavazis AN. Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury. Free Radic Biol Med 2008; 44(2):193–201.
   PubMed Web of Science ®Google Scholar
• Wong CM, Bansal G, Pavlickova L, Marcocci L, Suzuki YJ. Reactive oxygen species and antioxidants in pulmonary hypertension. Antioxid Redox Signal 2012; 2 [Epub ahead of print]. doi:10.1089/ars.2012.4568.
   Google Scholar
• Sladowska-Kozłowska J, Litwin M, Niemirska A, Oxidative stress in hypertensive children before and after 1 year of antihypertensive therapy. Pediatr Nephrol 2012; 27(10):1943–1951.
   PubMed Web of Science ®Google Scholar