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Original Articles

VEGF-A and VEGFR1 SNPs associate with preeclampsia in a Philippine population

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Pages 578-585 | Received 21 Jan 2016, Accepted 04 Mar 2016, Published online: 26 Sep 2016

References

  • Hutcheon JA, Lisonkova S, Joseph KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best Pract Res Clin Obstet Gynaecol 2011;25:391–403.
  • Turner JA. Diagnosis and management of pre-eclampsia: an update. Int J Women’s Health 2010;2:327–337. doi: 10.2147/IJWH.S8550.
  • Say L, Chou D, Gemmill A, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health 2014;2:e323–333.
  • Norwitz ER. Defective implantation and placentation: laying the blueprint for pregnancy complications. Reprod Biomed Online 2006;13:591–599.
  • Hoeben A, Landuyt B, Highley MS, et al. Vascular endothelial growth factor and angiogenesis. Pharmacol Rev 2004;56:549–580.
  • R Roskoski Jr. Vascular endothelial growth factor (VEGF) signaling in tumor progression. Crit Rev Oncol Hematol 2007;62:179–213.
  • Arcondéguy T, Lacazette E, Millevoi S, et al. VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level. Nucleic Acids Res 2013;41:7997–8010.
  • Gerber HP, McMurtrey A, Kowalski J, et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 1998;273:30336–30343.
  • Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029–1039.
  • Senger DR, Ledbetter SR, Claffey KP, et al. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 1996;149:293–305.
  • Charnock-Jones DS, Kaufmann P, Mayhew TM. Aspects of human fetoplacental vasculogenesis and angiogenesis. I. Molecular regulation. Placenta 2004;25:103–113.
  • Levine RJ, Maynard SE, Qian C, et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004;350:672–683.
  • Lymboussaki A, Olofsson B, Eriksson U, et al. Vascular endothelial growth factor (VEGF) and VEGF-C show overlapping binding sites in embryonic endothelia and distinct sites in differentiated adult endothelia. Circ Res 1999;85:992–999.
  • Kaipainen A, Korhonen J, Mustonen T, et al. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 1995;92:3566–3570.
  • Witmer AN, van Blijswijk BC, Dai J, et al. VEGFR-3 in adult angiogenesis. J Pathol 2001;195:490–497.
  • Kalkunte S, Mselle TF, Norris WE, et al. Vascular endothelial growth factor C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface. J Immunol 2009;182:4085–4092.
  • Rakova N, Muller DN, Staff AC, et al. Novel ideas about salt, blood pressure, and pregnancy. J Reprod Immunol 2014;101–102:135–139.
  • Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ 2005;330:565.
  • Hartikainen AL, Aliharmi RH, Rantakillo PT. A cohort study of epidemiologic associations and outcomes of pregnancies with hypertensive disorders. Hypertens Pregnancy 1998;17:31–41.
  • Ros HS, Cnattingius S, Lipworth L. Comparison of risk factors for pre-eclampsia and gestational hypertension in a population-based cohort study. Am J Epidemiol 1998;147:1062–1070.
  • Boyd HA, Tahir H, Wohlfahrt J, et al. Associations of personal and family preeclampsia history with the risk of early-, intermediate- and late-onset preeclampsia. Am J Epidemiol 2013;178:1611–1619.
  • Tubbergen P, Lachmeijer AM, Althuisius SM, et al. Change in paternity: a risk factor for preeclampsia in multiparous women? J Reprod Immunol 1999;45:81–88.
  • Robillard PY, Hulsey TC, Alexander GR,et al. Paternity patterns and risk of pre-eclampsia in the last pregnancy in multiparae. J Reprod Immunol 1993;24:1–12.
  • Cnattingius S, Reilly M, Pawitan Y, et al. Maternal and fetal genetic factors account for most of familial aggregation of preeclampsia: a population-based Swedish cohort study. Am J Med Genet A 2004;130A:365–371.
  • Bernard N, Giguère Y. Genetics of preeclampsia: what are the challenges? J Obstet Gynaecol Can 2003;25:578–585.
  • Dekker G, Robillard PY, Roberts C. The etiology of preeclampsia: the role of the father. J Reprod Immunol 2011;89:126–132.
  • Srinivas SK, Morrison AC, Andrela CM, et al. Allelic variations in angiogenic pathway genes are associated with preeclampsia. Am J Obstet Gynecol 2010;202:445.e1–11.
  • Shim JY, Jun JK, Jung BK, et al. Vascular endothelial growth factor gene +936 C/T polymorphism is associated with preeclampsia in Korean women. Am J Obstet Gynecol 2007;197:271.e1–4.
  • Papazoglou D, Galazios G, Koukourakis MI, et al. Vascular endothelial growth factor gene polymorphisms and pre-eclampsia. Mol Hum Reprod 2004;10:321–324.
  • Andraweera PH, Dekker GA, Dissanayake VH, et al. Vascular endothelial growth factor family gene polymorphisms in preeclampsia in Sinhalese women in Sri-Lanka. J Matern Fetal Neonatal Med 2013;26:532–536.
  • Ruggiero D, Dalmasso C, Nutile T, et al. Genetics of VEGF serum variation in human isolated populations of Cilento: importance of VEGF polymorphisms. PLoS One 2011;6:e16982.
  • Banyasz I, Szabo S, Bokodi G, et al. Genetic polymorphisms of vascular endothelial growth factor in severe pre-eclampsia. Mol Hum Reprod 2006;12:233–236.
  • Garza-Veloz I, Castruita-De la Rosa C, Cortes-Flores R, et al. No association between polymorphisms/haplotypes of the vascular endothelial growth factor gene and preeclampsia. BMC Pregnancy Childbirth 2011;11:35.
  • Chobanian AV, Bakris GL, Black HR, et al. The national high blood pressure education program coordinating committee. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension 2003;42:1206–1252.
  • Roberts JM, August PA, Bakris G, et al. Hypertension in pregnancy. Report of the American college of obstetricians and gynecologists’ task force on hypertension in pregnancy. Obstet Gynecol 2013;122:1122–1131.
  • Watson CJ, Webb NJ, Bottomley MJ, et al. Identification of polymorphisms within the vascular endothelial growth factor (VEGF) gene: correlation with variation in VEGF protein production. Cytokine 2000;12:1232–1235.
  • Stevens A, Soden J, Brenchley PE, et al. Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter. Cancer Res 2003;63:812–816.
  • Renner W, Kotschan S, Hoffmann C, et al. A common 936 C/T mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels. J Vasc Res 2000;37:443–448.
  • Solé X, Guinó E, Valls J, et al. SNPStats: a web tool for the analysis of association studies. Bioinformatics 2006;22:1928–1929.
  • Gauderman W, Morrison J. QUANTO 1.1: A computer program for power and sample size calculations for genetic-epidemiology studies. 2006. Available from: http://biostats.usc.edu/Quanto.html [last accessed 25 November 2015]
  • Rao AK, Cheng YW, Caughey AB. Perinatal complications among different Asian-American subgroups. Am J Obstet Gynecol 2006;194:e39–41.
  • Rao AK, Daniels K, El-Sayed YY, et al. Perinatal outcomes among Asian American and Pacific Islander women. Am J Obstet Gynecol 2006;195:834–838.
  • Glass D, Viñuela A, Davies MN, et al. UK Brain Expression consortium; MuTHER consortium, Durbin R, McCarthy MI, Deloukas P, Dermitzakis ET, Weale ME, Bataille V, Spector TD. Gene expression changes with age in skin, adipose tissue, blood and brain. Genome Biol 2013;14:R75.
  • Choquet H, Meyre D. Genetics of Obesity: what have we Learned? Curr Genomics 2011;12:169–179.
  • Reimer T, Koczan D, Gerber B, et al. Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes. Mol Hum Reprod 2002;8:674–680.
  • Eras JL, Saftlas AF, Triche E, et al. Abortion and its effect on risk of preeclampsia and transient hypertension. Epidemiology 2000;11:36–43.
  • Saftlas AF, Levine RJ, Klebanoff MA, et al. Abortion, changed paternity, and risk of preeclampsia in nulliparous women. Am J Epidemiol 2003;157:1108–1114.
  • Skjaerven R, Wilcox AJ, Lie RT. The interval between pregnancies and the risk of preeclampsia. N Engl J Med 2002;346:33–38.
  • Baker PN, Krasnow J, Roberts JM, et al. Elevated serum levels of vascular endothelial growth factor in patients with preeclampsia. Obstet Gynecol 1995;86:815–821.
  • Sharkey AM, Cooper JC, Balmforth JR, et al. Maternal plasma levels of vascular endothelial growth factor in normotensive pregnancies and in pregnancies complicated by pre-eclampsia. Eur J Clin Invest 1996;26:1182–1185.
  • Kupferminc MJ, Daniel Y, Englender T, et al. Vascular endothelial growth factor is increased in patients with preeclampsia. Am J Reprod Immunol 1997;38:302–306.
  • Hunter A, Aitkenhead M, Caldwell C, et al. Serum levels of vascular endothelial growth factor in preeclamptic and normotensive pregnancy. Hypertension 2000;36:965–969.
  • Murakami Y, Kobayashi T, Omatsu K, et al. Exogenous vascular endothelial growth factor can induce preeclampsia-like symptoms in pregnant mice. Semin Thromb Hemost 2005;31:307–313.
  • Maynard SE, Min JY, Merchan J, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt-1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 2003;111:649–658.
  • Bergmann A, Ahmad S, Cudmore M, et al. Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. J Cell Mol Med 2010;14:1857–1867.
  • Powe CE, Levine, RJ, Karumanchi SA. Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease. Circulation 2011;123:2856–2869.
  • Fan X, Rai A, Kambham N, et al. Endometrial VEGF induces placental sFlt-1 and leads to pregnancy complications. J Clin Invest 2014;124:4941–4952.
  • Zeisler H1, Llurba E, Chantraine F, et al. Predictive value of the sFlt-1:PlGF ratio in women with suspected Preeclampsia. N Engl J Med 2016;374(1):13–22.
  • Nagy B, Savli H, Molvarec A, et al. Vascular endothelial growth factor (VEGF) polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analyses. Clin Chim Acta 2008;389:126–131.
  • Ward LD, Kellis M. Interpreting noncoding genetic variation in complex traits and human disease. Nat Biotechnol 2012;30:1095–1106.

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