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Clinical and Experimental Hypertension Volume 17, 1995 - Issue 1-2
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Original Article

The One Hundred Percent Hypothesis: Glutamate Or Gaba in Synapses on Sympathetic Preganglionic Neurons

I. J. Llewellyn-Smith Hypertension Research Laboratory, Centre for Neuroscience and Department of Medicine, Flinders University, Bedford Park, South Australia, 5042, Australia
,
J. B. Minson Hypertension Research Laboratory, Centre for Neuroscience and Department of Medicine, Flinders University, Bedford Park, South Australia, 5042, Australia
,
P. M. Pilowsky Hypertension Research Laboratory, Centre for Neuroscience and Department of Medicine, Flinders University, Bedford Park, South Australia, 5042, Australia
,
L. F. Arnolda Hypertension Research Laboratory, Centre for Neuroscience and Department of Medicine, Flinders University, Bedford Park, South Australia, 5042, Australia
&
J. P. Chalmers Hypertension Research Laboratory, Centre for Neuroscience and Department of Medicine, Flinders University, Bedford Park, South Australia, 5042, Australia
Pages 323-333 | Published online: 03 Jul 2009

References

  • Chalmers J. P., Pilowsky P. M. Brainstem and bulbospinal neurotransmitter system in the control of blood pressure. J. Hypertension 1991; 9: 675–694
  • Mills E. H., Minson J. B., Pilowsky P. M., Chalmers J. P. N-methyl-D-aspartate receptors in the spinal cord mediate pressor responses to stimulation of the rostral ventrolateral medulla in the rat. Clin. Exp. Pharmacol. Physiol. 1988; 15: 147–155
  • Verberne A. J.M., Widdop R. E., Maccarone C., Jarrott B., Beart P. M., Louis W. J. Intrathecal kynurenate reduces arterial pressure, heart rate and baroreceptor-heart rate reflex in conscious rats. Neurosci. Letts. 1990; 114: 309–315
  • Kapoor V., Minson J., Chalmers J. Ventrolateral medulla stimulation increases blood pressure and spinal cord amino acid release. NeuroReports 1992; 3: 55–58
  • Backman S. B., Henry L. Effects of glutamate and aspartate on sympathetic preganglionic neurons in the upper thoracic intermediolateral nucleus of the cat. Brain Res 1983; 277: 370–374
  • Mo N., Dun N. J. Excitatory post-synaptic potentials in neonatal rat sympathetic preganglionic neurons: possible mediation by NMDA receptors. Neurosci. Letts. 1987; 74: 327–332
  • Minson J. B., Pilowsky P. M., Llewellyn-Smith I. J., Kaneko T., Kapoor V., Chalmers J. P. Glutamate in spinally projecting neurons of the rostral ventral medulla. Brain Res 1991; 555: 326–331
  • Llewellyn-Smith I. J., Phend K. D., Minson J. B., Pilowsky P. M., Chalmers J. P. Glutamate immunoreactive synapses on retrogradely labelled sympathetic preganglionic neurons in rat thoracic spinal cord. Brain Res. 1992; 581: 67–80
  • Backman S. B., Henry L. Effects of GABA and glycine on sympathetic preganglionic neurons in the upper thoracic intermediolateral nucleus of the cat. Brain Res. 1983; 277: 365–369
  • Yoshimura M., Nishi S. Intracellular recordings from lateral horn cells of the spinal cord in vitro. J. Autonom. Nerv. Syst 1982; 6: 5–11
  • Gordon F. Spinal GABA receptors and central cardiovascular control. Brain Res. 1985; 328: 165–169
  • Bacon S., Smith A. D. Preganglionic sympathetic neurones innervating the rat adrenal medulla: immunocytochemical evidence of synaptic input from nerve terminals containing substance P, GABA or 5-hydroxytryptamine. J. Autonom. Nerv. Syst. 1988; 24: 97–122
  • Bogan N., Mennone A., Cabot J. B. Light microscopic and ultrastructural localization of GABA-like immunoreactive input to retrogradely labeled sympathetic preganglionic neurons. Brain Res 1989; 505: 257–270
  • Llewellyn-Smith I. J., Pilowsky P., Minson J. B. Retrograde tracers for light or electron microscopy. Experimental Neuroanatomy: A Practical Approach, P Bolam. Oxford University Press, Oxford 1992; 31–59
  • Morrison S. F., Callaway J., Milner T. A., Reis D. J. Rostral ventrolateral medulla: A source of the glutamatergic innervation of the sympathetic intermediolateral nucleus. Brain Res 1991; 562: 126–135
  • Llewellyn-Smith I. J., Minson J. B., Pilowsky P. M., Chalmers J. P. There are few catecholamine or NPY-containing synapses in the intermediolateral cell column of rat thoracic spinal cord. Clin. Exp. Pharmacol. Physiol. 1991; 18: 111–115
  • Pilowsky P. M., Llewellyn-Smith I. J., Lipski J., Chalmers J. Substance P immunoreactive boutons form synapses with feline sympathetic preganglionic neurons. J. Comp. Neurol. 1992; 320: 121–135
  • Milner T. A., Morrison S. F., Abate C., Reis D. J. Phenylethanolamine N-methyltransferase-containing terminals synapse directly on sympathetic preganglionic neurons in the rat. Brain Research 1988; 448: 205–222
  • Vera P. L., Holets V. R., Miller K. E. Ultrastructural evidence of synaptic contacts between substance P-, enkephalin- and serotonin-immunoreactive terminals and retrogradely labeled sympathetic preganglionic neurons in the rat: A study using a double-peroxidase procedure. Synapse 1990; 6: 221–229
  • Cabot J. B., Alessi V., Bushnell A. Glycine-like immunoreactive input to sympathetic preganglionic neurons. Brain Res 1992; 571: 1–18
  • Ottersen O. P., Storm-Mathisen J., Somogyi P. Colocalization of glycine-like and GABA-like immunoreactivities in Golgi cell terminals in the rat cerebellum: a post-embedding light and electron microscopic immunocytochemical study. Brain Res. 1988; 450: 342–353

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