Black tea and theaflavins suppress various inflammatory modulators and i-NOS mediated nitric oxide synthesis during gastric ulcer healing

References

• Tarnawski A, Szabo IL, Husain SS, Soreghana B. Regeneration of gastric mucosa during ulcer healing is triggered by growth factors and signal transduction pathways. J Physiol - Paris 2001;95:337–344.
   PubMedGoogle Scholar
• Barrison AF, Wolfe MM. Management of NSAID-related gastrointestinal mucosal injury. Inflammopharmacol 1999;7: 277–286.
   PubMedGoogle Scholar
• Lanas A, Perez-Aisa MA, Feu F, Ponce J. A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with non-steroidal anti-inflammatory drug use. Am J Gastroenterol 2005;100:1685–1693.
   PubMed Web of Science ®Google Scholar
• Hawkins C, Hanks GW. The gastroduodenal toxicity of nonsteroidal anti-inflammatory drugs. A review of the literature. J Pain Symptom Management 2000;20:140–151.
   PubMed Web of Science ®Google Scholar
• Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, . Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995;83: 483–492.
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Naito Y, Kishi A, Tomii T, Kaneko T, Iinuma S, . Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut 1993;34:732–737.
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Naito Y. The role of neutrophils and inflammation in gastric mucosal injury. Free Radic Res 2000;33: 785–794.
   PubMed Web of Science ®Google Scholar
• Chatterjee M, Saluja R, Kanneganti S, Chinta S, Dikshit M. Biochemical and molecular evaluation of neutrophil NOS in spontaneously hypertensive rats. Cell Mol Biol 2007;53:84–92.
   PubMed Web of Science ®Google Scholar
• Salvemini D, de Nucci G, Gryglewski RJ, Vane JR. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc Natl Acad Sci USA 1989;86:6328–6332.
   PubMed Web of Science ®Google Scholar
• Kristal B, Shurtz-Swirski R, Chezar J, Manaster J, Levy R, Shapiro G, . Participation of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation in patients with essential hypertension. Am J Hypertens 1998;11:921–928.
   PubMed Web of Science ®Google Scholar
• Loria V, Dato I, Graziani F, Biasucci LM. Myeloperoxidase: a new biomarker of inflammation in ischemic heart disease and acute coronary syndromes. Mediat Inflamm 2008;2008: 135625. doi:10.1155/2008/135625.
   PubMed Web of Science ®Google Scholar
• Wu CC, Chen JS, Wu WM, Liao TN, Chu P, Lin SH, . Myeloperoxidase serves as a marker of oxidative stress during single haemodialysis session using two different biocompatible dialysis membranes. Nephrol Dial Transplant 2005;20: 1134–1139.
   PubMed Web of Science ®Google Scholar
• Nishida K, Ohta Y, Kobayashi T, Ishiguro I. Involvement of the xanthine-xanthine oxidase system and neutrophils in the development of acute gastric mucosal lesions in rats with water immersion restraint stress. Digestion 1997;58:340–351.
   PubMed Web of Science ®Google Scholar
• Whittle BJR. Nitric oxide in gastrointestinal physiology and pathology. Johnson LR. The physiology of the gastrointestinal tract. New York: Raven; 1994. 267–294.
   Google Scholar
• Ziche M, Morbidelli L, Masini E, Amerini S, Granger HJ, Maggi CA. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J Clin Invest 1994;94:2036–2044.
   PubMed Web of Science ®Google Scholar
• Souza MHLP, Lemos HP, Oliveira RB, Cunha FQ. Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor 1 (TNF-R1) or inducible nitric oxide synthase (iNOS) deficient mice. Gut 2004;53: 791–796.
   PubMed Web of Science ®Google Scholar
• Osborn L. Leukocyte adhesion to endothelium in inflammation. Cell 1990;62:3–6.
   PubMed Web of Science ®Google Scholar
• Wallace JL, Arfors KE, McKnight GW. A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. Gastroenterol 1991;100:878–883.
   PubMed Web of Science ®Google Scholar
• Wallace JL, McKnight W, Miyasaka M, Tamatani T, Paulson J, Anderson DC, . Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury. Am J Physiol 1993;265(Gastrointest Liver Physiol 28):G993–G998.
   Google Scholar
• Chan FKL. Primer: managing NSAID-induced ulcer complications—balancing gastrointestinal and cardiovascular risks. Nature Clin Practice Gastroenterol Hepatol 2006;3: 563–573.
   PubMedGoogle Scholar
• Levenstein S. Stress and peptic ulcer: life beyond Helicobacter. BMJ 1998;316:538–541.
   PubMed Web of Science ®Google Scholar
• FAO Committee on Commodity Problems. Intergovernmental Group on Tea. Tea consumption and human health. Sess. 9. Rome, Italy, 7–10 October 1991, report no. FAO-ESC–CCP/TE-91/4.
   Google Scholar
• Maity S, Vedasiromoni JR, Ganguly DK. Role of glutathione in the antiulcer effect of hot water extract of black tea (Camellia sinensis). Jpn J Pharmacol 1998;78:285–292.
   PubMedGoogle Scholar
• Maity S, Vedasiromoni JR, Chaudhuri L, Ganguly DK. Role of reduced glutathione and nitric oxide in the black tea extract-mediated protection against ulcerogen-induced changes in motility and gastric emptying in rats. Jpn J Pharmacol 2001;85:358–364.
   PubMedGoogle Scholar
• Adhikary B, Yadav SK, Roy K, Bandyopadhyay SK, Chattopadhyay S. Black tea and theaflavins assist healing of indomethacin-induced gastric ulceration in mice by antioxidative action. Evidence-Based Compl Alt Med (eCAM) 2010;2011:Article ID 546560, doi:10.1155/2011/546560.
   Web of Science ®Google Scholar
• Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994;298:249–258.
   PubMed Web of Science ®Google Scholar
• Banerjee D, Maity B, Bauri AK, Bandyopadhyay SK, Chattopadhyay S. Gastroprotective property of Myristica malabarica against indomethacin-induced stomach ulceration: a mechanistic exploration. J Pharm Pharmacol 2007;59: 1555–1565.
   PubMed Web of Science ®Google Scholar
• Dokmeci D, Akpolat M, Aydogu N, Doganay L, Turan FN. L-Carntine inhibits ethanol-induced gastric mucosal injury in rats. Pharmacol Rep 2005;57:481–488.
   PubMed Web of Science ®Google Scholar
• Beck WL, Xavier R. Mechanism of NSAID induced gastrointestinal injury defined using mutant mice. Gastroenterol 2000;119:699–705.
   PubMed Web of Science ®Google Scholar
• Suzuki K, Ota H, Sasagawa S, Sakatani T, Fujikura T. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983;132:345–352.
   PubMed Web of Science ®Google Scholar
• Ma L, Wallace JL. Endothelial nitric oxide synthase modulates gastric ulcer healing in rats. Am J Physiol Gastrointest Liver Physiol 2000;279:G341–G346.
   PubMed Web of Science ®Google Scholar
• Biswas K, Bandyopadhyay U, Chattopadhyay I, Varadaraj A, Ali E, Banerjee RK. A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. J Biol Chem 2003;278:10993–11001.
   PubMed Web of Science ®Google Scholar
• Ganguly K, Kundu P, Banerjee A, Reiter RJ, Swarnakar S. Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants. Free Radic Biol Med 2006;41:911–925.
   PubMed Web of Science ®Google Scholar
• Fiorucci S, Antonelli E, Morelli A. Mechanism of non-steroidal anti-inflammatory drug-gastropathy. Dig Liv Dis 2001;31(Suppl 2):S35–S43.
   Google Scholar
• Tegeder I, Pfeilschifter J, Geisslinger G. Cyclooxygenase-independent actions of cyclooxygenase inhibitors. FASEB J 2001;15:2057–2072.
   PubMed Web of Science ®Google Scholar
• Tarnawski AS, Jones MK. Inhibition of angiogenesis by NSAIDs: molecular mechanism and clinical applications. J Mol Med 2003;81:627–636.
   PubMed Web of Science ®Google Scholar
• Wallace JL, Keenan CM, Granger DN. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. Am J Physiol 1990;259:G462–G467.
   PubMed Web of Science ®Google Scholar
• Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterol 1984;87:1344–1350.
   PubMed Web of Science ®Google Scholar
• Piotrowski J, Slomiany A, Slomiany BL. Activation of apoptotic caspase-3 and nitric oxide synthase-2 in gastric mucosal injury induced by indomethacin. Scand J Gastroenterol 1999;34:129–134.
   PubMed Web of Science ®Google Scholar
• Luo JC, Shin VY, Liu ESL, So WHL, Ye YN, Chang FY, Cho CH. Non-ulcerogenic dose of dexamethasone delays gastric ulcer healing in rats. J Pharm Exp Thearp 2003;307:692–698.
   PubMed Web of Science ®Google Scholar
• Morton J, Coles B, Wright K, Gallimore A, Morrow JD, Terry ES, . Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFN gamma-dependent iNOS expression in the vasculature of healthy mice. Blood 2008;111:5187–5194.
   PubMed Web of Science ®Google Scholar
• Goldstein JL, Johanson JF, Hawkey CJ, Suchower LJ, Brown KA. Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy – A randomized study comparing ranitidine with esomeprazole. Aliment Pharmacol Ther 2007;26:1101–1111.
   PubMed Web of Science ®Google Scholar
• Takeuchi Y, Kitano S, Bandoh T, Matsumoto T, Baatar D, Kai S. Acceleration of gastric ulcer healing by omeprazole in portal hypertensive rats. Is its action mediated by gastrin release and the stimulation of epithelial proliferation? Eur Surg Res 2003;35:75–80.
   PubMed Web of Science ®Google Scholar
• Glowinska B, Urban M, Peczynska J, Florys B. Soluble adhesion molecules (sICAM-1, sVCAM-1) and selectins (sE selectin, sP selectin, sL selectin) levels in children and adolescents with obesity, hypertension, and diabetes. Metabolism 2005;54:1020–1026.
   PubMed Web of Science ®Google Scholar
• Panés J, Perry M, Granger DN. Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention. Br J Pharmacol 1999;126:537–550.
   PubMed Web of Science ®Google Scholar
• Brzozowski T, Konturek PC, Konturek SJ, Sliwowski Z, Pajdo R, Drozdowicz D, . Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers. Microsc Res Tech 2001;43: 343–353.
   Google Scholar
• Appleyard CB, McCafferty DM, Tigley AW, Swain MG, Wallace JL. Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence. Am J Physiol 1996;270:G42–G48.
   PubMed Web of Science ®Google Scholar
• Chatterjee S, Premachandran S, Bagewadikar RS, Bhattacharya S, Chattopadhyay S, Poduval TB. Arginine metabolic pathways determine its therapeutic benefit in experimental heat stroke: role of Th1/Th2 cytokine balance. Nitric Oxide 2006;15:408–416.
   PubMed Web of Science ®Google Scholar