Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat

References

• Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813–820.
   PubMed Web of Science ®Google Scholar
• Biessels GJ, Gispen WH. The impact of diabetes on cognition: what can be learned from rodent models? Neurobiol Aging 2005;1:36–41.
   Google Scholar
• Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006;5:64–74.
   PubMed Web of Science ®Google Scholar
• Gispen WH, Biessels GJ. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 2000;23:542–549.
   PubMed Web of Science ®Google Scholar
• Li ZG, Zhang W, Sima AA. The role of impaired insulin/IGF action in primary diabetic encephalopathy. Brain Res 2005; 1037:12–24.
   PubMed Web of Science ®Google Scholar
• Mijnhout GS, Scheltens P, Diamant M, Biessels GJ, Wessels AM, Simsek S, . Diabetic encephalopathy: a concept in need of a definition. Diabetologia 2006;49:1447–1448.
   PubMed Web of Science ®Google Scholar
• Trudeau F, Gagnon S, Massicotte G. Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus. Eur J Pharmacol 2004;490:177–186.
   PubMed Web of Science ®Google Scholar
• Tuzcu M, Baydas G. Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats. Eur J Pharmacol 2006;537:106–110.
   PubMed Web of Science ®Google Scholar
• Brands AM, Kessels RP, de Haan EH, Kappelle LJ, Biessels GJ. Cerebral dysfunction in type 1 diabetes: effects of insulin, vascular risk factors and blood-glucose levels. Eur J Pharmacol 2004;490:159–168.
   PubMed Web of Science ®Google Scholar
• Osawa T, Kato Y. Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia. Ann N Y Acad Sci 2005;1043:440–451.
   PubMed Web of Science ®Google Scholar
• Aragno M, Parola S, Brignardello E, Mauro A, Tamagno E, Manti R, . Dehydroepiandrosterone prevents oxidative injury induced by transient ischemia/reperfusion in the brain of diabetic rats. Diabetes 2000;49:1924–1931.
   PubMed Web of Science ®Google Scholar
• Hayashi T, Hirshman MF, Fujii N, Habinowski SA, Witters LA, Goodyear LJ. Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism. Diabetes 2000;49:527–531.
   PubMed Web of Science ®Google Scholar
• Terai K, Hiramoto Y, Masaki M, Sugiyama S, Kuroda T, Hori M, . AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol 2005;25:9554–9575.
   PubMed Web of Science ®Google Scholar
• Kim YW, Lee SM, Shin SM, Hwang SJ, Brooks JS, Kang HE, . Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. Free Radic Biol Med 2009;47:1082–1092.
   PubMed Web of Science ®Google Scholar
• Culmsee C, Monnig J, Kemp BE, Mattson MP. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. J Mol Neurosci 2001;17:45–58.
   PubMed Web of Science ®Google Scholar
• McCullough LD, Zeng Z, Li H, Landree LE, McFadden J, Ronnett GV. Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke. J Biol Chem 2005;280:20493–20502.
   PubMed Web of Science ®Google Scholar
• Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, . Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787–790.
   PubMed Web of Science ®Google Scholar
• Ahmad M, Saleem S, Ahmad AS, Yousuf S, Ansari MA, Khan MB, . Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences. J Neurochem 2005;93:94–104.
   PubMed Web of Science ®Google Scholar
• Ishrat T, Khan MB, Hoda MN, Yousuf S, Ahmad M, Ansari MA, . Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats. Behav Brain Res 2006;171:9–16.
   PubMed Web of Science ®Google Scholar
• Masuda T, Hidaka K, Shinohara A, Maekawa T, Takeda Y, Yamaguchi H. Chemical studies on antioxidant mechanism of curcuminoid: analysis of radical reaction products from curcumin. J Agric Food Chem 1999;47:71–77.
   PubMed Web of Science ®Google Scholar
• Srimal RC, Dhawan BN. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 1973;25:447–452.
   PubMed Web of Science ®Google Scholar
• Kim JM, Araki S, Kim DJ, Park CB, Takasuka N, Baba-Toriyama H, . Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1,2-dimethylhydrazine initiation. Carcinogenesis 1998;19:81–85.
   PubMed Web of Science ®Google Scholar
• Dairam A, Limson JL, Watkins GM, Antunes E, Daya S. Curcuminoids, curcumin,and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats. J Agric Food Chem 2007;55:1039–1044.
   PubMed Web of Science ®Google Scholar
• Rajakrishnan V, Viswanathan P, Rajasekharan KN, Menon VP. Neuroprotective role of curcumin from curcuma longa on ethanol-induced brain damage. Phytother Res 1999;13: 571–574.
   PubMed Web of Science ®Google Scholar
• Unnikrishnan MK, Rao MN. Curcumin inhibits nitrogen dioxide induced oxidation of hemoglobin. Mol Cell Biochem 1995;146:35–37.
   PubMed Web of Science ®Google Scholar
• Kuhad A, Chopra K. Curcumin attenuates diabetic encephalopathy in rats: behavioral and biochemical evidences. Eur J Pharmacol 2007;576:34–42.
   PubMed Web of Science ®Google Scholar
• Thandavarayan RA, Watanabe K, Ma M, Gurusamy N, Veeraveedu PT, Konishi T, . Dominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus. Am J Physiol Heart Circ Physiol 2009;297:H911–H919.
   PubMed Web of Science ®Google Scholar
• Kamboj SS, Sandhir R. Protective effect of N-acetylcysteine supplementation on mitochondrial oxidative stress and mitochondrial enzymes in cerebral cortex of streptozotocin-treated diabetic rats. Mitochondrion 2011;11:214–222.
   PubMed Web of Science ®Google Scholar
• Allen RG, Tresini M. Oxidative stress and gene regulation. Free Radic Biol Med 2000;28:463–499.
   PubMed Web of Science ®Google Scholar
• Russell JW, Sullivan KA, Windebank AJ, Herrmann DN, Feldman EL. Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiol Dis 1999;6:347–363.
   PubMed Web of Science ®Google Scholar
• Folmer V, Soares JC, Rocha JB. Oxidative stress in mice is dependent on the free glucose content of the diet. Int J Biochem Cell Biol 2002;34:1279–1285.
   PubMed Web of Science ®Google Scholar
• Maritim AC, Sanders RA, Watkins JB. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 2003;17:24–38.
   PubMed Web of Science ®Google Scholar
• Pierrefiche G, Topall G, Courboin G, Henriet I, Laborit H. Antioxidant activity of melatonin in mice. Res Commun Chem Pathol Pharmacol 1993;80:211–223.
   PubMedGoogle Scholar
• Tucci P, Cione E, Perri M, Genchi G. All-trans-retinoic acid induces apoptosis in Leydig cells via activation of the mitochondrial death pathway and antioxidant enzyme regulation. J Bioenerg Biomembr 2008;40:315–323.
   PubMed Web of Science ®Google Scholar
• Al-Shabrawey M, Bartoli M, El-Remessy AB, Platt DH, Matragoon S, Behzadian MA, . Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy. Am J Pathol 2005;167:599–607.
   PubMed Web of Science ®Google Scholar
• Arias C, Montiel T, Quiroz-Báez R, Massieu L. Beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease. Exp Neurol 2002;176:163–174.
   PubMed Web of Science ®Google Scholar
• Oakhill JS, Scott JW, Kemp BE. Structure and function of AMP-activated protein kinase. Acta Physiol 2009;196:3–14.
   PubMed Web of Science ®Google Scholar
• Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, . Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2003;2:28.
   PubMedGoogle Scholar
• Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, . Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2005;2:9–19.
   PubMed Web of Science ®Google Scholar
• Xie M, Zhang D, Dyck JR, Li Y, Zhang H, Morishima M, . A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci 2006;103:17378–17383.
   PubMed Web of Science ®Google Scholar
• Birnbaum MJ. Activating AMP-activated protein kinase without AMP. Mol Cell 2005;19:289–290.
   PubMed Web of Science ®Google Scholar
• Park IJ, Hwang JT, Kim YM, Ha J, Park OJ. Differential modulation of AMPK signaling pathways by low or high levels of exogenous reactive oxygen species in colon cancer cells. Ann N Y Acad Sci 2006;1091:102–109.
   PubMed Web of Science ®Google Scholar
• Emerling BM, Weinberg F, Snyder C, Burgess Z, Mutlu GM, Viollet B, . Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radic Biol Med 2009;46:1386–1391.
   PubMed Web of Science ®Google Scholar
• Slot JW, Geuze HJ, Gigengack S, James DE, Lienhard GE. Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat. Proc Natl Acad Sci 1991;88:7815–7819.
   PubMed Web of Science ®Google Scholar
• Fischer Y, Böttcher U, Eblenkamp M, Thomas J, Jüngling E, Rösen P, Kammermeier H. Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes. Biochem J 1997;321:629–638.
   PubMed Web of Science ®Google Scholar
• Kim T, Davis J, Zhang AJ, He X, Mathews ST. Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochem Biophys Res Commun 2009;388: 377–382.
   PubMed Web of Science ®Google Scholar
• Dagon Y, Avraham Y, Magen I, Gertler A, Ben-Hur T, Berry EM. Nutritional status, cognition, and survival: a new role for leptin and AMP kinase. J Biol Chem 2005;280:42142–42148.
   PubMed Web of Science ®Google Scholar
• Kowaltowski AJ, Castilho RF, Vercesi AE. Mitochondrial permeability transition and oxidative stress. FEBS Lett 2001; 495:12–15.
   PubMed Web of Science ®Google Scholar