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Research Article

Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE

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Pages 1029-1043 | Received 24 May 2012, Accepted 24 May 2012, Published online: 25 Jun 2012

References

  • Riley PA. Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int J Radiat Biol 1994;65: 27–33.
  • Schmidt-Ullrich RK, Dent P, Grant S, Mikkelsen RB, Valerie K. Signal transduction and cellular radiation responses. Radiat Res 2000;153:245–257.
  • Wallace SS. Enzymatic processing of radiation-induced free radical damage in DNA. Radiat Res 1998;150(5 Suppl):S60–S79.
  • Majima HJ, Indo HP, Tomita K, Suenaga S, Motoori S, Kato H, . Intracellular oxidative stress caused by ionizing radiation. In: Singh K., editor. Oxidative Stress, Disease and Cancer. London: Imperial College Press; 2006. pp. 61–83.
  • Buettner GR, Jurkiewicz BA. Catalytic metals, ascorbate and free radicals: combinations to avoid. Radiat Res 1996;145: 532–541.
  • Motoori S, Majima HJ, Ebara M, Kato H, Hirai F, Kakinuma S, . Overexpression of mitochondrial manganese superoxide dismutase protects against radiation-induced cell death in the human hepatocellular carcinoma cell line HLE. Cancer Res 2001;61:5382–5388.
  • Ho Y-S, Crapo JD. Isolation and characterization of complementary DNAs encoding human manganese-containing superoxide dismutase. FEBS Lett 1988;229:256–260.
  • Lithgow T. Targeting of proteins to mitochondria. FEBS Lett 2000;476:22–26.
  • Mihara K, Omura T. Cytoplasmic chaperones in precursor targeting to mitochondria: the role of MSF and hsp70. Trends in Cell Biol 1996;6:104–108.
  • Dor I, Namba M, Sato J. Establishment and some biological characteristics of human hepatoma cell lines. Gann 1975;66:385–392.
  • Beauchamp C, Fridovich I. Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal Biochem 1971;44:276–287.
  • Setsukinai K, Urano Y, Kakinuma K, Majima HJ, Nagano T. Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J Biol Chem 2003;278:3170–3175.
  • Ogura A, Oowada S, Kon Y, Hirayama A, Yasui H, Meike S, . Redox regulation in radiation-induced cytochrome c release from mitochondria of human lung carcinoma A549 cells, Cancer Lett 2009;277:64–71.
  • Toyokuni S, Miyake N, Hiai H, Hagiwara M, Kawakishi S, Osawa T, . The monoclonal antibody specific for the 4-hydroxy-2-nonenal histidine adduct. FEBS Lett 1995;359: 189–191.
  • Rouser G, Siakotos AN, Fleischer S. Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots. Lipids 1966:1;85–86.
  • Dent P, Yacoub A, Contessa J, Caron R, Amorino G, Valerie K, . Stress and radiation-induced activation of multiple intracellular signaling pathways. Radiat Res 2003;159:283–300.
  • Hosokawa Y, Sakakura Y, Tanaka L, Okumura K, Yajima T, Kaneko M, . Radiation-induced apoptosis is independent of caspase-8 but dependent on cytochrome c and the caspase-9 cascade in human leukemia HL60 cells. J Radiat Res 2005;46;293–303.
  • Hall HJ. DNA strand breaks and chromosomal aberrations. In: Hall HJ, editor. Radiobiology for the Radiologist 4th ed. Philadelphia: JB Lippencott Company; 1994. pp. 15–27.
  • Kerr JFR, Searle J. Apoptosis: Its nature and kinetic role. In: Meyn RE, Withers HR, editors. Radiation Biology in Cancer Research. New York: Raven Press; 1980. pp. 367–384.
  • Hengartner MO. The biochemistry of apoptosis. Nature 2000;407:770–776.
  • Rich T, Allen RL, Wyllie AH. Defying death after DNA damage. Nature 2000;407:777–783.
  • Epperly MW, Gretton JE, Sikora CA, Jefferson M, Bernarding M, Nie S, . Mitochondrial localization of superoxide dismutase is required for decreasing radiation-induced cellular damage. Radiat Res 2003;160:568–578.
  • Gakh O, Cavadini P, Isaya G. Mitochondrial processing peptides. Biochim Biophys Acta 2002;1592:63–77.
  • Leach JK, Tuyle GV, Lin P-S, Schmidt-Ullrich R, Mikkelsen RB. Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen. Cancer Res 2001;61:3894–3901.
  • Majima HJ, Oberley TD, Furukawa K, Mattson MP, Yen H-C, Szweda LI, . Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death. J Biol Chem 1998;273:8217–8224.
  • Hirai F, Motoori S, Kakinuma S, Tomita K, Indo HP, Kato H, . Mitochondrial signal lacking manganese superoxide dismutase failed to prevent cell death by reoxygenation following hypoxia in a human pancreatic cancer cell line, KP4. Antioxid Redox Signal 2004;6:523–535.
  • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde, and related aldehydes. Free Radic Biol Med 1991;11:81–128.
  • Boveris A, Cadenas E. Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration. FEBS Lett 1975;54:311–314.
  • Takeshige K, Minakami S. NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation. Biochem J 1979;180:129–135.
  • Weisiger RA, Fridovich I. Mitochondrial superoxide dismutase. J Biol Chem 1973;248:4793–4796.
  • Imai H, Nakagawa Y. Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radic Biol Med. 2003;34:145–169.
  • Nakagawa Y. Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor. Biol Pharm Bull. 2004;27:956–960.
  • Kagan VE, Tyurin VA, Jiang J, Tyurina YY, Ritov VB, Amoscato AA, . Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors. Nat Chem Biol 2005:1;223–232.
  • Dayal D, Martin SM, Owens KM, Aykin-Burns N, Zhu Y, Boominathan A, . Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation. Radiat Res. 2009;172:737–745.
  • Barjaktarovic Z, Schmaltz D, Shyla A, Azimzadeh O, Schulz S, Haagen J, . Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays. PLoS One 2011;6:e27811. Epub 2011 Dec 8.
  • Indo HP, Davidson M, Yen H-C, Suenaga S, Tomita K, Nishii T, . Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. Mitochondrion 2007;7:106–118.
  • Majima HJ, Indo HP, Suenaga S, Kaneko T, Matsui H, Yen H-C, . Mitochondria as Source of Free Radicals. In: Naito Y, Suematsu M, Yoshikawa T, editors. Free Radical Biology in Digestive Diseases, Front Gastrointest Res. Basel, Karger; 2011. vol 29, pp 12–22.
  • Majima HJ, Indo HP, Tomita K, Iwashita Y, Suzuki H, Masuda D, . Bio-assessment of risk in long-term manned space exploration – cell death factors in space radiation and/or microgravity: a review -. Biol Sci Space 2009;23:43–53.
  • Majima HJ, Indo HP, Suenaga S, Matsui H, Yen H-C, Ozawa T, . Mitochondria as Possible pharmaceutical targets for the effects of vitamin E and its homologues in oxidative stress-related diseases. Curr Pharm Des 2011;17: 2190–2195.
  • Blough NV, Zafiriou OC. Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution. Inorg Chem 1985;24:3502–3504.
  • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990;87:1620–1624.
  • Keller JN, Kindy MS, Holtsberg FW, St Clair DK, Yen H-C, Germeyer A, . Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J Neurosci 1998;18: 687–697.
  • Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys 1991;288:481–487.
  • Pryor WA, Porter NA. Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. Free Radic Biol Med 1990;8:541–543.

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