554
Views
38
CrossRef citations to date
0
Altmetric
Research Article

Baicalin protects human skin fibroblasts from ultraviolet A radiation-induced oxidative damage and apoptosis

, , , , , , & show all
Pages 1458-1471 | Received 01 Jul 2012, Accepted 29 Aug 2012, Published online: 24 Sep 2012

References

  • Marionnet C, Pierrard C, Lejeune F, Sok J, Thomas M, Bernerd F. Different oxidative stress response in keratinocytes and fibroblasts of reconstructed skin exposed to non extreme daily-ultraviolet radiation. PLoS One 2010;5:e12059.
  • Yaar M, Gilchrest BA. Photoageing: mechanism, prevention and therapy. Br J Dermatol 2007;157:874–887.
  • Halliday GM, Byrne SN, Damian DL. Ultraviolet A radiation: its role in immunosuppression and carcinogenesis. Semin Cutan Med Surg 2011;30:214–221.
  • D'Angio CT, Finkelstein JN. Oxygen regulation of gene expression: a study in opposites. Mol Genet Metab 2000;71: 371–380.
  • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44–84.
  • Petersen AB, Gniadecki R, Vicanova J, Thorn T, Wulf HC. Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in HaCaT keratinocytes. J Photochem Photobiol B 2000;59:123–131.
  • Verna LK, Chen D, Schluter G, Williams GM. Inhibition by singlet oxygen quenchers of oxidative damage to DNA produced in cultured cells by exposure to a quinolone antibiotic and ultraviolet A irradiation. Cell Biol Toxicol 1998;14:237–242.
  • Roos WP, Kaina B, DNA damage-induced apoptosis: From specific DNA lesions to the DNA damage response and apoptosis. Cancer Lett 2012.
  • Hirota A, Kawachi Y, Itoh K, Nakamura Y, Xu X, Banno T, . Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: protective role in UVA- induced apoptosis. J Invest Dermatol 2005;124:825–832.
  • Estaquier J, Vallette F, Vayssiere JL, Mignotte B. The mitochondrial pathways of apoptosis. Adv Exp Med Biol 2012;942:157–183.
  • Kroemer G, Petit P, Zamzami N, Vayssière JL, Mignotte B. The biochemistry of programmed cell death. FASEB J 1995;9: 1277–1287.
  • Cai J, Yang J, Jones DP. Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta 1998;1366: 139–149.
  • Shieh DE, Liu LT, Lin CC. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res 2000;20:2861–2865.
  • Liou SF, Hsu JH, Liang JC, Ke HJ, Chen IJ, Wu JR, . San-Huang-Xie-Xin-Tang protects cardiomyocytes against hypoxia/reoxygenation injury via inhibition of oxidative stress-induced apoptosis. J Nat Med 2012;66:311–320.
  • Wen YF, Zhao JQ, Bhadauria M, Nirala SK. Baicalin prevents cadmium induced hepatic cytotoxicity, oxidative stress and histomorphometric alterations. Exp Toxicol Pathol 2011.
  • Zhang Y, Gao Z, Liu J, Xu Z. Protective effects of baicalin and quercetin on an iron-overloaded mouse: comparison of liver, kidney and heart tissues. Nat Prod Res 2011;25:1150–1160.
  • Lee JH, Kim GH. Evaluation of antioxidant and inhibitory activities for different subclasses flavonoids on enzymes for rheumatoid arthritis. J Food Sci 2010;75:H212–H217.
  • Bing-Rong Z, Song-Liang J, Xiao-EC, Xiang-Fei L, Bao-Xiang C, Jie G, . Protective effect of the Baicalin against DNA damage induced by ultraviolet B irradiation to mouse epidermis. Photodermatol Photoimmunol Photomed 2008;24:175–182.
  • Zhou BR, Lin BJ, Jin SL, Luo D. Mitigation of acute ultraviolet B radiation-mediated damages by baicalin in mouse skin. Photodermatol Photoimmunol Photomed 2009;25:250–258.
  • Zhou BR, Liu WL, Luo D. Protective effect of baicalin against multiple ultraviolet B exposure-mediated injuries in C57BL/6 mouse skin. Arch Pharm Res 2011;34:261–268.
  • Zhou BR, Luo D, Wei FD, Chen XE, Gao J. Baicalin protects human fibroblasts against ultraviolet B-induced cyclobutane pyrimidine dimers formation. Arch Dermatol Res 2008;300: 331–334.
  • Kojima H, Urano Y, Kikuchi K, Higuchi T, Hirata Y, Nagano T. Fluorescent Indicators for Imaging Nitric Oxide Production. Angew Chem Int Ed Engl 1999;38:3209–3212.
  • Benov L, Sztejnberg L, Fridovich I. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radic Biol Med 1998;25:826–831.
  • Kalyanaraman B, Darley-Usmar V, Davies KJ, Dennery PA, Forman HJ, Grisham MB, . Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations. Free Radic Biol Med 2012;52:1–6.
  • Peng N, Liu JT, Guo F, Li R. Epigallocatechin-3-gallate inhibits interleukin-6- and angiotensin II-induced production of C-reactive protein in vascular smooth muscle cells. Life Sci 2010;86: 410–415.
  • Li Z, Shi K, Guan L, Cao T, Jiang Q, Yang Y, . ROS leads to MnSOD upregulation through ERK2 translocation and p53 activation in selenite-induced apoptosis of NB4 cells. FEBS Lett 2010;584:2291–2297.
  • Gao P, Guo RW, Chen JF, Chen Y, Wang H, Yu Y, . A meprin inhibitor suppresses atherosclerotic plaque formation in ApoE-/-mice. Atherosclerosis 2009;207:84–92.
  • Fan J, Cai H, Yang S, Yan L, Tan W. Comparison between the effects of normoxia and hypoxia on antioxidant enzymes and glutathione redox state in ex vivo culture of CD34(+) cells. Comp Biochem Physiol B Biochem Mol Biol 2008;151: 153–158.
  • Mendis E, Kim MM, Rajapakse N, Kim SK. An in vitro cellular analysis of the radical scavenging efficacy of chitooligosaccharides. Life Sci 2007;80:2118–2127.
  • Xiang H, McSurdy-Freed J, Moorthy GS, Hugger E, Bambal R, Han C, . Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor. J Pharm Sci 2006;95: 2657–2672.
  • Lambert AJ, Brand MD. Reactive oxygen species production by mitochondria. Methods Mol Biol 2009;554:165–181.
  • Shi H, Zhao B, Xin W. Scavenging effects of baicalin on free radicals and its protection on erythrocyte membrane from free radical injury. Biochem Mol Biol Int 1995;35: 981–994.
  • Sim GS, Lee BC, Cho HS, Lee JW, Kim JH, Lee DH, . Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast. Arch Pharm Res 2007;30:290–298.
  • Moysan A, Marquis I, Gaboriau F, Santus R, Dubertret L, Morlière P. Ultraviolet A-induced lipid peroxidation and antioxidant defense systems in cultured human skin fibroblasts. J Invest Dermatol 1993;100:692–698.
  • Saelens X, Festjens N, Vande Walle L, van Gurp M, van Loo G, Vandenabeele P. Toxic proteins released from mitochondria in cell death. Oncogene 2004;23:2861–2874.
  • Oplander C, Cortese MM, Korth HG, Kirsch M, Mahotka C, Wetzel W, . The impact of nitrite and antioxidants on ultraviolet-A-induced cell death of human skin fibroblasts. Free Radic Biol Med 2007;43:818–829.
  • Xue C, Liu W, Wu J, Yang X, Xu H. Chemoprotective effect of N-acetylcysteine (NAC) on cellular oxidative damages and apoptosis induced by nano titanium dioxide under UVA irradiation. Toxicol In Vitro 2011;25:110–116.
  • Slater AF, Nobel CS, Maellaro E, Bustamante J, Kimland M, Orrenius S. Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis. Biochem J 1995;306:771–778.
  • Pustisek N, Situm M. UV-radiation, apoptosis and skin. Coll Antropol 2011;35:339–341.
  • Patrick L. Lead toxicity part II: the role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity. Altern Med Rev 2006;11:114–127.
  • Rocha M, Hernandez-Mijares A, Garcia-Malpartida K, Bañuls C, Bellod L, Victor VM. Mitochondria-targeted antioxidant peptides. Curr Pharm Des 2010;16:3124–3131.
  • Liu B, Jian Z, Li Q, Li K, Wang Z, Liu L, . Baicalein protects Human melanocytes from H(2)O(2)-induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway. Free Radic Biol Med 2012;53:183–193.
  • Godar DE. UVA1 radiation triggers two different final apoptotic pathways. J Invest Dermatol 1999;112:3–12.
  • Tada-Oikawa S, Oikawa S, Kawanishi S. Role of ultraviolet A-induced oxidative DNA damage in apoptosis via loss of mitochondrial membrane potential and caspase-3 activation. Biochem Biophys Res Commun 1998;247:693–696.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.