Nanocarrier: A potential tool for future antioxidant therapy

References

• Moroney JT, Bagiella E, Desmond DW, Paik MC, Stern Y, Tatemichi TK. Risk factors for incident dementia after stroke. Role of hypoxic and ischemic disorders. Stroke 1996;27: 1283–1289.
   Google Scholar
• Wilson WR, Hay MP. Targeting hypoxia in cancer therapy. Nat Rev Cancer 2011;11:393–410.
   PubMed Web of Science ®Google Scholar
• Margaill I, Plotkine M, Lerouet D. Antioxidant strategies in the treatment of stroke. Free Radic Biol Med 2005;39: 429–443.
   PubMed Web of Science ®Google Scholar
• Kaliora AC, Dedoussis GV, Schmidt H. Dietary antioxidants in preventing atherogenesis. Atherosclerosis 2006;187:1–17.
   PubMed Web of Science ®Google Scholar
• Roleira FMF, Tavares-da-Silva EJ, Garrido J, Borges F. Antioxidant and stroke: success and pitfalls. Transl Stroke Res 2012;6:117–143.
   Google Scholar
• Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, et al. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem 2008;8: 1395–1406.
   PubMed Web of Science ®Google Scholar
• Tan C, Nakajima M.β-carotene nanodispersions: preparation, characterization and stability evaluation. J Food Chem 2005;92:661–671.
   Web of Science ®Google Scholar
• Hollman PCH, van Trijp JMP, Buysman MNCP, van de Gaag MS, Mengelers MJB, de Vries JHM, Katan MB. Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man. FEBS Lett 1997;418:152–156.
   PubMed Web of Science ®Google Scholar
• Wahlstrom B, Blennow G. A study on the fate of curcumin in the rat. Acta Pharmacol Toxicol (Copenh) 1978;43:86–92.
   PubMedGoogle Scholar
• Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010;464:1067–1070.
   PubMed Web of Science ®Google Scholar
• Templeton AC, Hostetler MJ, Warmoth EK, Chen S, Hartshorn CM, Krishnamurthy VM, et al. Gateway reactions to diverse, polyfunctional monolayer-protected gold clusters. J Am Chem Soc 1998;120:4845–4849.
   Web of Science ®Google Scholar
• Cerecetto H, Lopez GV. Antioxidants derived from vitamin E: an overview. Mini Rev Med Chem 2007;7:315–338.
   PubMed Web of Science ®Google Scholar
• Mukai K, Okabe K, Hosose H. Synthesis and stopped-flow investigation of antioxidant activity of tocopherols: finding of new tocopherol derivatives having the highest antioxidant activity among phenolic antioxidants. J Org Chem 1989;54: 557–560.
   Web of Science ®Google Scholar
• Hussain HH, Babic G, Durst T, Wright JS, Flueraru M, Chichirau A, Chepelev LL. Development of novel antioxidants: design, synthesis, and reactivity. J Org Chem 2003;68:7023–7032.
   PubMed Web of Science ®Google Scholar
• Chichirau A, Flueraru M, Chepelev LL, Wright JS, Willmore WG, Durst T, et al. Mechanism of cytotoxicity of catechols and a naphthalenediol in PC12-AC cells: the connection between extracellular autoxidation and molecular electronic structure. Free Radic Biol Med 2005;38:344–355.
   PubMed Web of Science ®Google Scholar
• Nie Z, Liu KJ, Zhong C-J, Wang L-F, Yang Y, Tian Q, Liu Y. Enhanced radical scavenging activity by antioxidant-functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidants. Free Radic Biol Med 2007;43:1243–1254.
   PubMed Web of Science ®Google Scholar
• Du L, Suo S, Wang G, Jia H, Liu KJ, Zhao B, Liu Y. Mechanism and cellular kinetic studies of the enhancement of antioxidant activity by using surface-functionalized gold nanoparticles. Chem Eur J 2013;19:1281–1287.
   PubMed Web of Science ®Google Scholar
• Ferry DR, Smith A, Maikhandi J, Fyfe DW, de Takats PG, Anderson D, et al. Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res 1996;2:659–668.
   PubMed Web of Science ®Google Scholar
• Wu TH, Yen FL, Lin LT, Tsai TR, Lin CC, Cham TM. Preparation, physicochemical characterization, and antioxidant effects of quercetin nanoparticles. Int J Pharm 2008;346:160–168.
   PubMed Web of Science ®Google Scholar
• Anand P, Nair HB, Sung B, Kunnumakkara AB, Yadav VR, Tekmal RR, Aggarwal BB. Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo. Biochem Pharmacol 2010;79:330–338.
   PubMed Web of Science ®Google Scholar
• Correa F, Buelna M, Hernandez-Resendiz S, García-Niño WR, Roldán FJ, Soto V, et al. Curcumin maintains cardiac and mitochondrial function in chronic kidney diseases. Free Radic Biol Med 2013;61:119–129.
   PubMed Web of Science ®Google Scholar
• Doggui S, Sahni JK, Arseneault M, Dao L, Ramassamy C. Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line. J Alzheimers Dis 2012;30:377–392.
   PubMed Web of Science ®Google Scholar
• Grama CN, Suryanarayana P, Patil MA, Raghu G, Balakrishna N, Kumar MN, Reddy GB. Efficacy of biodegradable curcumin nanoparticles in delaying cataract in diabetic rat model. PLoS One 2013;8:e78217.
   PubMed Web of Science ®Google Scholar
• Ahmad N, Umar S, Ashafaq M, Akhtar M, Iqbal Z, Samim M, Ahmad FJ. A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin, and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke. Protoplasma 2013;250:1327–1338.
   PubMed Web of Science ®Google Scholar
• Yen FL, Wu TH, Tzeng CW, Lin LT, Lin CC. Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities. J Agric Food Chem 2010;58:7376–7382.
   PubMed Web of Science ®Google Scholar
• Yen FL, Tsai MH, Yang CM, Liang CJ, Lin CC, Chiang YC, et al. Curcumin nanoparticles ameliorate ICAM-1 expression in TNF-alpha-treated lung epithelial cells through p47 (phox) and MAPKs/AP-1 pathways. PLoS One 2013;8:e63845.
   Google Scholar
• Sonaje K, Italia JL, Sharma G, Bhardwaj V, Tikoo K, Kumar MN. Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats. Pharm Res 2007;24:899–908.
   PubMed Web of Science ®Google Scholar
• Lu X, Xu H, Sun B, Zhu Z, Zheng D, Li X. Enhanced neuroprotective effects of resveratrol delivered by nanoparticles on hydrogen peroxide-induced oxidative stress in rat cortical cell culture. Mol Pharm 2013;10:2045–2053.
   PubMed Web of Science ®Google Scholar
• Al Shaal L, Shegokar R, Muller RH. Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation. Int J Pharm 2011;420:133–140.
   PubMed Web of Science ®Google Scholar
• Zhou L, Chen M, Tian L, Guan Y, Zhang Y. Release of polyphenolic drugs from dynamically bonded layer-by-layer films. ACS Appl Mater Interfaces 2013;5:3541–3548.
   PubMed Web of Science ®Google Scholar
• Astete CE, Dolliver D, Whaley M, Khachatryan L, Sabliov CM. Antioxidant poly(lactic-co-glycolic) acid nanoparticles made with alpha-tocopherol-ascorbic acid surfactant. ACS Nano 2011;5:9313–9325.
   PubMed Web of Science ®Google Scholar
• Behl G, Sharma M, Sikka M, Dahiya S, Chhikara A, Chopra M. Gallic acid loaded disulfide cross-linked biocompatible polymeric nanogels as controlled release system: synthesis, characterization, and antioxidant activity. J Biomater Sci Polym Ed 2013;24:865–881.
   PubMed Web of Science ®Google Scholar
• Warner DS, Shen H, Batinic-Haberle I. Oxidants, antioxidants and the ischemic brain. J Exp Biol 2004;207:3221–3231.
   PubMed Web of Science ®Google Scholar
• Hu P, Tirelli N. Scavenging ROS: superoxide dismutase/catalase mimetics by the use of an oxidation-sensitive nanocarrier/enzyme conjugate. Bioconjug Chem 2012;23:438–449.
   PubMed Web of Science ®Google Scholar
• Klyachko NL, Manickam DS, Brynskikh AM, Uglanova SV, Li S, Higginbotham SM, et al. Cross-linked antioxidant nanozymes for improved delivery to CNS. Nanomedicine 2012;8:119–129.
   PubMed Web of Science ®Google Scholar
• Reddy MK, Labhasetwar V. Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injury. FASEB J 2009;23: 1384–1395.
   PubMed Web of Science ®Google Scholar
• Trombino S, Cassano R, Muzzalupo R, Pingitore A, Cione E, Picci N. Stearyl ferulate-based solid lipid nanoparticles for the encapsulation and stabilization of beta-carotene and alpha-tocopherol. Colloids Surf B Biointerfaces 2009;72:181–187.
   PubMed Web of Science ®Google Scholar
• Zhang L, Hayes DG, Chen G, Zhong Q. Transparent dispersions of milk-fat-based nanostructured lipid carriers for delivery of beta-carotene. J Agric Food Chem 2013;61: 9435–9443.
   PubMed Web of Science ®Google Scholar
• Cai Y, Anavy ND, Chow HHS. Contribution of presystemic hepatic extraction to the low oral bioavailability of green tea catechins in rats. Drug Metab Dispos 2002;30:1246–1249.
   PubMed Web of Science ®Google Scholar
• Dvorakova K, Dorr RT, Valcic S, Timmermann B, Alberts DS. Pharmacokinetics of the green tea derivative, EGCG, by the topical route of administration in mouse and human skin. Cancer Chemother Pharmacol 1999;43:331–335.
   PubMed Web of Science ®Google Scholar
• Hu B, Pan C, Sun Y, Hou Z, Ye H, Zeng X. Optimization of fabrication parameters to produce chitosan-tripolyphosphate nanoparticles for delivery of tea catechins. J Agric Food Chem 2008;56:7451–7458.
   PubMed Web of Science ®Google Scholar
• Peres I, Rocha S, Gomes J, Morais S, Pereira MC, Coelho M. Preservation of catechin antioxidant properties loaded in carbohydrate nanoparticles. Carbohydr Polym 2011;86: 147–153.
   Web of Science ®Google Scholar
• Huang SJ, Sun SL, Chiu CC, Wang LF. Retinol-encapsulated water-soluble succinated chitosan nanoparticles for antioxidant applications. J Biomater Sci Polym Ed 2013;24: 315–329.
   PubMed Web of Science ®Google Scholar
• Felice F, Zambito Y, Belardinelli E, D’Onofrio C, Fabiano A, Balbarini A, Di Stefano R. Delivery of natural polyphenols by polymeric nanoparticles improves the resistance of endothelial progenitor cells to oxidative stress. Eur J Pharm Sci 2013;50:393–399.
   PubMed Web of Science ®Google Scholar
• Felice F, Zambito Y, Di Colo G, D’Onofrio C, Fausto C, Balbarini A, Di Stefano R. Red grape skin and seeds polyphenols: evidence of their protective effects on endothelial progenitor cells and improvement of their intestinal absorption. Eur J Pharm Biopharm 2012;80:176–184.
   PubMed Web of Science ®Google Scholar
• Cheng Y, Cai H, Yin B, Yao P. Cholic acid modified N-(2-hydroxy)-propyl-3-trimethylammonium chitosan chloride for superoxide dismutase delivery. Int J Pharm 2013;454: 425–434.
   PubMed Web of Science ®Google Scholar
• Cabral H, Matsumoto Y, Mizuno K, Chen Q, Murakami M, Kimura M, et al. Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 2011;6:815–823.
   PubMed Web of Science ®Google Scholar
• Jiang W, Kim BYS, Rutka JT, Chan WCW. Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnol 2008;3:145–150.
   PubMed Web of Science ®Google Scholar
• Yadav A, Lomash V, Samim M, Flora SJ. Curcumin encapsulated in chitosan nanoparticles: a novel strategy for the treatment of arsenic toxicity. Chem Biol Interact 2012;199: 49–61.
   PubMed Web of Science ®Google Scholar
• Han L, Du L-B, Kumar A, Jia H-Y, Liang X-J, Tian Q, Nie G-J, Liu Y. Inhibitory effects of trolox-encapsulated chitosan nanoparticles on tert-butylhydroperoxide induced RAW264.7 apoptosis. Biomaterials 2012;33:8517–8528.
   PubMed Web of Science ®Google Scholar
• Fang R, Hao R, Wu X, Li Q, Leng X, Jing H. Bovine serum albumin nanoparticle promotes the stability of quercetin in simulated intestinal fluid. J Agric Food Chem 2011;59: 6292–6298.
   PubMed Web of Science ®Google Scholar
• Li B, Du W, Jin J, Du Q. Preservation of (-)-epigallocatechin-3-gallate antioxidant properties loaded in heat treated beta-lactoglobulin nanoparticles. J Agric Food Chem 2012;60:3477–3484.
   PubMed Web of Science ®Google Scholar
• Hu B, Ting Y, Zeng X, Huang Q. Bioactive peptides/chitosan nanoparticles enhance cellular antioxidant activity of (-)-epigallocatechin-3-gallate. J Agric Food Chem 2013;61: 875–881.
   PubMed Web of Science ®Google Scholar
• Sanna V, Roggio AM, Siliani S, Piccinini M, Marceddu S, Mariani A, Sechi M. Development of novel cationic chitosan-and anionic alginate-coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol. Int J Nanomed 2012;7:5501–5516.
   PubMed Web of Science ®Google Scholar
• Karewicz A, Bielska D, Gzyl-Malcher B, Kepczynski M, Lach R, Nowakowska M. Interaction of curcumin with lipid monolayers and liposomal bilayers. Colloid Surf B Biointerfaces 2011;88:231–239.
   PubMed Web of Science ®Google Scholar
• Takahashi M, Uechi S, Takara K, Asikin Y, Wada K. Evaluation of an oral carrier system in rats: bioavailability and antioxidant properties of liposome-encapsulated curcumin. J Agric Food Chem 2009;57:9141–9146.
   PubMed Web of Science ®Google Scholar
• Rashidinejad A, Birch EJ, Sun-Waterhouse D, Everett DW. Delivery of green tea catechin and epigallocatechin gallate in liposomes incorporated into low-fat hard cheese. Food Chem 2014;156:176–183.
   PubMed Web of Science ®Google Scholar
• Fang J-Y, Hwang T-L, Huang Y-L, Fang C-L. Enhancement of the transdermal delivery of catechins by liposomes incorporating anionic surfactants and ethanol. Int J Pharm 2006;310:131–138.
   PubMed Web of Science ®Google Scholar
• Furukawa R, Yamada Y, Takenaga M, Igarashi R, Harashima H. Octaarginine-modified liposomes enhance the anti-oxidant effect of Lecithinized superoxide dismutase by increasing its cellular uptake. Biochem Biophys Res Commun 2011;404:796–801.
   PubMed Web of Science ®Google Scholar
• Chen YP, Chen CT, Hung Y, Chou CM, Liu TP, Liang MR, Mou CY. A new strategy for intracellular delivery of enzyme using mesoporous silica nanoparticles: superoxide dismutase. J Am Chem Soc 2013;135:1516–1523.
   PubMed Web of Science ®Google Scholar
• Shaji J, Varkey D. Silica-coated solid lipid nanoparticles enhance antioxidant and antiradical effects of meloxicam. J Pharm Investigation 2013;43:405–416.
   Google Scholar
• Huang B, Zhang J, Hou J, Chen C. Free radical scavenging efficiency of Nano-Se in vitro. Free Radic Biol Med 2003;35:805–813.
   PubMed Web of Science ®Google Scholar
• Wei H, Wang EK. Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes. Chem Soc Rev 2013;42:6060–6093.
   PubMed Web of Science ®Google Scholar
• Gao LZ, Zhuang J, Nie L, Zhang JB, Zhang Y, Gu N, et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol 2007;2:577–583.
   PubMed Web of Science ®Google Scholar
• Yin H. Quest for better antioxidants: a commentary on “Enhanced radical-scavenging activity by antioxidant- functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidant”. Free Radic Biol Med 2007;43:1229–1230.
   PubMed Web of Science ®Google Scholar
• Du L, Huang S, Zhuang Q, Jia H, Rockenbauer A, Liu P, Liu KJ, Liu Y. Highly sensitive free radical detection by nitrone-functionalized gold nanoparticles. Nanoscale 2014;6:1646–1652.
   PubMed Web of Science ®Google Scholar
• Gao X, Hu G, Qian Z, Ding Y, Zhang S, Wang D, Yang M. Immobilization of antioxidant on nanosilica and the antioxidative behavior in low density polyethylene. Polymer 2007;48:7309–7315.
   Web of Science ®Google Scholar
• Deligiannakis Y, Sotiriou GA, Pratsinis SE. Antioxidant and antiradical SiO2 nanoparticles covalently functionalized with gallic acid. ACS Appl Mater Interfaces 2012;4:6609–6617.
   PubMed Web of Science ®Google Scholar
• Mathew A, Fukuda T, Nagaoka Y, Hasumura T, Morimoto H, Yoshida Y, et al. Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer's disease. PLoS One 2012;7:e32616.
   PubMed Web of Science ®Google Scholar
• Yang YX, Song ZM, Cheng B, Xiang K, Chen XX, Liu JH, et al. Evaluation of the toxicity of food additive silica nanoparticles on gastrointestinal cells. J Appl Toxicol 2014;34: 424–435.
   PubMed Web of Science ®Google Scholar
• Mossman BT, Churg A. Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med 1998;157:1666–1680.
   PubMed Web of Science ®Google Scholar
• Saffiotti U. Lung cancer induction by crystalline silica. Prog Clin Biol Res 1992;374:51–69.
   PubMedGoogle Scholar
• Khlebtsov N, Dykman L. Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies. Chem Soc Rev 2011;40:1647–1671.
   PubMed Web of Science ®Google Scholar