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ORIGINAL ARTICLE

Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide

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Pages 210-218 | Received 27 Jul 2014, Accepted 26 Nov 2014, Published online: 23 Jan 2015

References

  • Kaunitz JD. Barrier function of gastric mucus. Keio J Med 1999;48:63–68.
  • Song X, Chen HX, Wang XY, Deng XY, Xi YX, He Q, et al. H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2. Cell Immunol 2013;286:22–30.
  • Li W, Jiang MZ. [Relationship between tight junction proteins and Helicobacter pylori-associated gastric diseases]. Zhongguo Dang Dai Er Ke Za Zhi 2014;16:242–247.
  • Kimura Y, Shiozaki H, Hirao M, Maeno Y, Doki Y, Inoue M, et al. Expression of occludin, tight-junction-associated protein, in human digestive tract. Am J Pathol 1997;151:45–54.
  • Grandi D, Solenghi E, Massi M, Morini G. Peripheral infusion of nociceptin/orphanin FQ influences the response of rat gastric and colonic mucosa to repeated stress. Regulatory Peptides 2010;160:49–56.
  • Chatterjee S, Chatterjee A, Roy S, Bera B, Bandyopadhyay SK. L-Theanine healed NSAID-induced gastric ulcer by modulating pro/antioxidant balance in gastric ulcer margin. J Nat Med 2014;68:699–708.
  • Hashimoto K, Oshima T, Tomita T, Kim Y, Matsumoto T, Joh T, Miwa H. Oxidative stress induces gastric epithelial permeability through claudin-3. Biochem Biophys Res Commun 2008;376:154–157.
  • Hirokawa M, Miura S, Yoshida H, Kurose I, Shigematsu T, Hokari R, et al. Oxidative stress and mitochondrial damage precedes gastric mucosal cell death induced by ethanol administration. Alcohol Clin Exp Res 1998;22:111s–114s.
  • Levonen AL, Hill BG, Kansanen E, Zhang J, Darley-Usmar VM. Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics. Free Radic Biol Med 2014;71:196–207.
  • Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 2005;1:84–91.
  • Onodera J, Ohsumi Y. Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation. J Biol Chem 2005;280:31582–31586.
  • Kiffin R, Bandyopadhyay U, Cuervo AM. Oxidative stress and autophagy. Antioxid Redox Signal 2006;8:152–162.
  • Sakiyama T, Musch MW, Ropeleski MJ, Tsubouchi H, Chang EB. Glutamine increases autophagy under basal and stressed conditions in intestinal epithelial cells. Gastroenterology 2009;136:924–932.
  • Benjamin JL, Sumpter R, Levine B, Hooper LV. Intestinal epithelial autophagy is essential for host defense against invasive bacteria. Cell Host Microbe 2013;13:723–734.
  • Li X, He D, Zhang L, Xue Y, Cheng X, Luo Y. Pyrrolidine dithiocarbamate attenuate shock wave induced MDCK cells injury via inhibiting nuclear factor-kappa B activation. Urol Res 2007;35:193–199.
  • Lv RL, Xu XY, Luo Z, Shen N, Wang F, Zhao YB. Pyrrolidine dithiocarbamate (PDTC) inhibits the overexpression of MCP-1 and attenuates microglial activation in the hippocampus of a pilocarpine-induced status epilepticus rat model. Exp Ther Med 2014;7:39–45.
  • Chen K, Long YM, Wang H, Lan L, Lin ZH. Activation of nuclear factor-kappa B and effects of pyrrolidine dithiocarbamate on TNBS-induced rat colitis. World J Gastroenterol 2005;11:1508–1514.
  • Nurmi A, Goldsteins G, Narvainen J, Pihaja R, Ahtoniemi T, Grohn O, Koistinaho J. Antioxidant pyrrolidine dithiocarbamate activates Akt-GSK signaling and is neuroprotective in neonatal hypoxia-ischemia. Free Radic Biol Med 2006;40:1776–1784.
  • Cuzzocrea S, Chatterjee PK, Mazzon E, Dugo L, Serraino I, Britti D, et al. Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation. Br J Pharmacol 2002;135:496–510.
  • Ye HH, Hua R, Yu L, Wu KJ, Fei SJ, Qin X, et al. Abnormal expression of toll-like receptor 4 is associated with susceptibility to ethanol-induced gastric mucosal injury in mice. Dig Dis Sci 2013;58:2826–2839.
  • Ren W, Liu S, Chen S, Zhang F, Li N, Yin J, et al. Dietary L-glutamine supplementation increases Pasteurella multocida burden and the expression of its major virulence factors in mice. Amino Acids 2013;45:947–955.
  • Yin J, Wu MM, Xiao H, Ren WK, Duan JL, Yang G, et al. Development of an antioxidant system after early weaning in piglets. J Anim Sci 2013;92:612–619.
  • Yin J, Ren WK, Wu XS, Yang G, Wang J, Li TJ, et al. Oxidative stress-mediated signaling pathways: A review. J Food Agri Environ 2013;11:132–139.
  • Yen WJ, Chyau CC, Lee CP, Chu HL, Chang LW, Duh PD. Cytoprotective effect of white tea against H2O2-induced oxidative stress in vitro. Food Chem 2013;141:4107–4114.
  • Zhang YB, Zhao W, Zeng RX. Autophagic degradation of caspase-8 protects U87MG cells against H2O2-induced oxidative stress. Asian Pac J Cancer Prev 2013;14: 4095–4099.
  • Tsukita S, Furuse M, Itoh M. Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol 2001;2:285–293.
  • Shin K, Fogg VC, Margolis B. Tight junctions and cell polarity. Annu Rev Cell Dev Biol 2006;22:207–235.
  • Matter K, Balda MS. Signalling to and from tight junctions. Nat Rev Mol Cell Biol 2003;4:225–236.
  • Pietrocola F, Izzo V, Niso-Santano M, Vacchelli E, Galluzzi L, Maiuri MC, Kroemer G. Regulation of autophagy by stress-responsive transcription factors. Semin Cancer Biol 2013;23:310–322.
  • He H, Liu X, Lv L, Liang H, Leng B, Zhao D, et al. Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress. Cell Death Dis 2014;5:e997.
  • Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007;39:596–604.
  • Sun Y, Zhao Y, Hou L, Zhang X, Zhang Z, Wu K. RRR- alpha-tocopheryl succinate induces apoptosis in human gastric cancer cells via the NF-kappaB signaling pathway. Oncol Rep 2014;32:1243–1248.
  • Wan F, Lenardo MJ. The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives. Cell Res 2010;20:24–33.
  • Copetti T, Demarchi F, Schneider C. p65/RelA binds and activates the beclin 1 promoter. Autophagy 2009;5:858–859.
  • Siggers RH, Hackam DJ. The role of innate immune-stimulated epithelial apoptosis during gastrointestinal inflammatory diseases. Cell Mol Life Sci 2011;68:3623–3634.
  • Zeng M, Wei X, Wu Z, Li W, Li B, Zhen Y, et al. NF-kappaB-mediated induction of autophagy in cardiac ischemia/reperfusion injury. Biochem Biophys Res Commun 2013;436:180–185.
  • Correa-Betanzo J, Allen-Vercoe E, McDonald J, Schroeter K, Corredig M, Paliyath G. Stability and biological activity of wild blueberry (Vaccinium angustifolium) polyphenols during simulated in vitro gastrointestinal digestion. Food Chem 2014;165:522–531.
  • Aihara E, Closson C, Matthis AL, Schumacher MA, Engevik AC, Zavros Y, Montrose MH. Motility and chemotaxis mediate the preferential colonization of gastric injury sites by helicobacter pylori. PLoS Pathog 2014;10:e1004275.
  • Wardill HR, Bowen JM. Chemotherapy-induced mucosal barrier dysfunction: an updated review on the role of intestinal tight junctions. Curr Opin Support Palliat Care 2013;7: 155–161.
  • Yu YB, Li YQ. Enteric glial cells and their role in the intestinal epithelial barrier. World J Gastroenterol 2014;20: 11273–11280.
  • Guttman JA, Finlay BB. Tight junctions as targets of infectious agents. Biochim Biophys Acta 2009;1788:832–841.
  • Suzuki T, Hara H. Quercetin enhances intestinal barrier function through the assembly of zonnula occludens-2, occludin, and claudin-1 and the expression of claudin-4 in caco-2 cells. J Nutr 2009;139:965–974.
  • Kiviluoto T, Ahonen M, Back N, Happola O, Mustonen H, Paimela H, Kivilaakso E. Preepithelial mucus-HCO-3 layer protects against intracellular acidosis in acid-exposed gastric-mucosa. Am J Physiol 1993;264:G57–G63.
  • Ivan AL, Campanini MZ, Martinez RM, Ferreira VS, Steffen VS, Vicentini FT, et al. Pyrrolidine dithiocarbamate inhibits UVB-induced skin inflammation and oxidative stress in hairless mice and exhibits antioxidant activity in vitro. J Photochem Photobiol B 2014;138C:124–133.
  • Abd-El-Fattah MA, Abdelakader NF, Zaki HF. Pyrrolidine dithiocarbamate protects against scopolamine-induced cognitive impairment in rats. Eur J Pharmacol 2014;723:330–338.
  • Moon SK, Jung SY, Choi YH, Lee YC, Patterson C, Kim CH. PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21(Cip1) expression: Involvement of p38 mitogen-activated protein kinase. J Cell Physiol 2004;198:310–323.
  • Kim YE, Park JA, Nam KH, Kwon HJ, Lee Y. Pyrrolidine dithiocarbamate-induced activation of ERK and increased expression of c-Fos in mouse embryonic stem cells. Bmb Reports 2009;42:148–153.
  • Li YY, Gao C, Shi YR, Tang YH, Liu L, Xiong T, et al. Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway. Toxicol Appl Pharmacol 2013;273:53–58.
  • Moore MN, Allen JI, Somerfield PJ. Autophagy: role in surviving environmental stress. Mar Environ Res 2006; 62 Suppl:S420–S425.
  • Jiang L, Yuan F, Dong J. Comment on Park et al.: High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells. Int Orthop 2014;38:675–676.
  • Luo C, Li Y, Wang H, Feng Z, Li Y, Long J, Liu J. Mitochondrial accumulation under oxidative stress is due to defects in autophagy. J Cell Biochem 2013;114:212–219.
  • Pal R, Palmieri M, Loehr JA, Li S, Abo-Zahrah R, Monroe TO, et al. Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy. Nat Commun 2014;5:4425.
  • Chen JW, Ni BB, Li B, Yang YH, Jiang SD, Jiang LS. The responses of autophagy and apoptosis to oxidative stress in nucleus pulposus cells: implications for disc degeneration. Cell Physiol Biochem 2014;34:1175–1189.
  • Li Y, Shen H, Shi J, Tang L. The effects of alpha lipoic acid in preventing oxidative stress-induced retinal pigment epithelial cell injury. Can J Physiol Pharmacol 2014;92:765–772.
  • Banan A, Shaikh M, Zhang L, Fields JZ, Fartiadi A, Keshavarzian A. Fundamental role of NF-kB activation in etch-induced iNOS driven oxidative stress injury to barrier integrity (BI) of gut epithelium. Alcohol Clin Exp Res 2006;30:14a–14a.

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