Analysis of the oxidative damage of DNA, RNA, and their metabolites induced by hyperglycemia and related nephropathy in Sprague Dawley rats

References

• International Diabetes Federation.2013. Diabetes Atlas. 6th ed. Brussels, Belgium: International Diabets Federation.
   Google Scholar
• Haligur M, Topsakal S, Ozmen O. Early degenerative effects of diabetes mellitus on pancreas, liver, and kidney in rats: an immunohistochemical study. Exp Diabetes Res 2012; 2012:120645.
   PubMed Web of Science ®Google Scholar
• Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005;54:1615–1625.
   PubMed Web of Science ®Google Scholar
• Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813–820.
   PubMed Web of Science ®Google Scholar
• Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787–790.
   PubMed Web of Science ®Google Scholar
• Barciszewski J, Barciszewska MZ, Siboska G, Rattan SI, Clark BF. Some unusual nucleic acid bases are products of hydroxyl radical oxidation of DNA and RNA. Mol Biol Rep 1999;26:231–238.
   PubMed Web of Science ®Google Scholar
• David SS, O’Shea VL, Kundu S. Base-excision repair of oxidative DNA damage. Nature 2007;447:941–950.
   PubMed Web of Science ®Google Scholar
• Hofer T, Seo AY, Prudencio M, Leeuwenburgh C. A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration. Biol chem 2006;387:103–111.
   PubMed Web of Science ®Google Scholar
• Gan W, Nie B, Shi F, Xu XM, Qian JC, Takagi Y, et al. Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging. Free Radic Biol Med 2012;52:1700–1707.
   PubMed Web of Science ®Google Scholar
• Shi F, Nie B, Gan W, Zhou XY, Takagi Y, Hayakawa H, et al. Oxidative damage of DNA, RNA and their metabolites in leukocytes, plasma and urine of Macaca mulatta: 8-oxoguanosine in urine is a useful marker for aging. Free Radic Res 2012; 46:1093–1098.
   PubMed Web of Science ®Google Scholar
• Nie B, Gan W, Shi F, Hu GX, Chen LG, Hayakawa H, et al. Age-dependent accumulation of 8-oxoguanine in the DNA and RNA in various rat tissues. Oxid Med Cell Longev 2013; 2013:303181.
   PubMed Web of Science ®Google Scholar
• Poulsen HE, Specht E, Broedbaek K, Henriksen T, Ellervik C, Mandrup-Poulsen T, et al. RNA modifications by oxidation: a novel disease mechanism? Free Rad Biol Med 2012;52: 1353–1361.
   PubMed Web of Science ®Google Scholar
• Broedbaek K, Siersma V, Henriksen T, Weimann A, Petersen M, Andersen JT, et al. Urinary markers of nucleic acid oxidation and long-term mortality of newly diagnosed type 2 diabetic patients. Diabetes care 2011;34:2594–2596.
   PubMed Web of Science ®Google Scholar
• Broedbaek K, Siersma V, Henriksen T, Weimann A, Petersen M, Andersen JT, et al. Association between urinary markers of nucleic acid oxidation and mortality in type 2 diabetes: a population-based cohort study. Diabetes care 2013; 36:669–676.
   PubMed Web of Science ®Google Scholar
• Park KS, Kim JH, Kim MS, Kim JM, Kim SK, Choi JY, et al. Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats. Diabetes 2001;50:2837–2841.
   PubMed Web of Science ®Google Scholar
• Jiang H, Fang J, Wu B, Yin G, Sun L, Qu J, et al. Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy. J Neuroinflamm 2011;8:119.
   PubMed Web of Science ®Google Scholar
• Gedik CM, Collins A, Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study. FASEB J 2005;19:82–84.
   PubMed Web of Science ®Google Scholar
• Chao MR, Yen CC, Hu CW. Prevention of artifactual oxidation in determination of cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction. Free Radic Biol Med 2008;44:464–473.
   PubMed Web of Science ®Google Scholar
• Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, Ames BN. DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proc Natl Acad Sci U S A 1998;95:288–293.
   PubMed Web of Science ®Google Scholar
• Kasai H. A new automated method to analyze urinary 8-hydroxydeoxyguanosine by a high-performance liquid chromatography-electrochemical detector system. J Radiat Res 2003;44:185–189.
   PubMed Web of Science ®Google Scholar
• Lin HS, Jenner AM, Ong CN, Huang SH, Whiteman M, Halliwell B. A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2’-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction. Biochem J 2004;380: 541–548.
   PubMed Web of Science ®Google Scholar
• Henriksen T, Hillestrom PR, Poulsen HE, Weimann A. Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2’-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry. Free Radic Biol Med 2009;47:629–635.
   PubMed Web of Science ®Google Scholar
• Poulsen HE, Nadal LL, Broedbaek K, Nielsen PE, Weimann A. Detection and interpretation of 8-oxo-dGsn and 8-oxoGua in urine, plasma and cerebrospinal fluid. Biochim Biophys Acta 2014;1840:801–808.
   PubMed Web of Science ®Google Scholar
• Weimann A, Broedbaek K, Henriksen T, Stovgaard ES, Poulsen HE. Assays for urinary biomarkers of oxidatively damaged nucleic acids. Free Radic Res 2012;46:531–540.
   PubMed Web of Science ®Google Scholar
• Simone S, Gorin Y, Velagapudi C, Abboud HE, Habib SL. Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2′-deoxyguanosine-DNA glycosylase. Diabetes 2008;57:2626–2636.
   PubMed Web of Science ®Google Scholar
• Altan N, Sepici-Dincel A, Sahin D, Kocamanoglu N, Kosova F, Engin A. Oxidative DNA damage: the thyroid hormone-mediated effects of insulin on liver tissue. Endocrine 2010;38: 214–220.
   PubMed Web of Science ®Google Scholar
• Nishikawa T, Sasahara T, Kiritoshi S, Sonoda K, Senokuchi T, Matsuo T, et al. Evaluation of urinary 8-hydroxydeoxy-guanosine as a novel biomarker of macrovascular complications in type 2 diabetes. Diabetes care 2003;26:1507–1512.
   PubMed Web of Science ®Google Scholar
• Corkey BE. Banting lecture 2011: hyperinsulinemia: cause or consequence? Diabetes 2012;61:4–13.
   PubMed Web of Science ®Google Scholar
• Kakimoto M, Inoguchi T, Sonta T, Yu HY, Imamura M, Etoh T, et al.Accumulation of 8-hydroxy-2′-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats. Diabetes 2002;51:1588–1595.
   PubMed Web of Science ®Google Scholar
• Hinokio Y, Suzuki S, Hirai M, Suzuki C, Suzuki M, Toyota T. Urinary excretion of 8-oxo-7, 8-dihydro-2′-deoxyguanosine as a predictor of the development of diabetic nephropathy. Diabetologia 2002;45:877–882.
   PubMed Web of Science ®Google Scholar
• Shin CS, Moon BS, Park KS, Kim SY, Park SJ, Chung MH, et al. Serum 8-hydroxy-guanine levels are increased in diabetic patients. Diabetes care 2001;24:733–737.
   PubMed Web of Science ®Google Scholar
• Jacobs AC, Resendiz MJ, Greenberg MM. Direct strand scission from a nucleobase radical in RNA. J Am Chem Soc 2010;132:3668–3669.
   PubMed Web of Science ®Google Scholar
• Kamiya H, Suzuki A, Yamaguchi Y, Handa H, Harashima H. Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5′-triphosphate by bacterial and human RNA polymerases. Free Radic Biol Med 2009;46:1703–1707.
   PubMed Web of Science ®Google Scholar
• Tanaka M, Chock PB, Stadtman ER. Oxidized messenger RNA induces translation errors. Proc Natl Acad Sci U S A 2007;104:66–71.
   PubMed Web of Science ®Google Scholar
• Shan X, Chang Y, Lin CL. Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression. FASEB J 2007;21:2753–2764.
   PubMed Web of Science ®Google Scholar
• Seo AY, Hofer T, Sung B, Judge S, Chung HY, Leeuwenburgh C. Hepatic oxidative stress during aging: effects of 8% long-term calorie restriction and lifelong exercise. Antioxid Redox Sign 2006;8:529–538.
   PubMed Web of Science ®Google Scholar
• Weimann A, Belling D, Poulsen HE. Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry. Nucleic acids research 2002;30:E7.
   PubMed Web of Science ®Google Scholar
• King GL, Kunisaki M, Nishio Y, Inoguchi T, Shiba T, Xia P. Biochemical and molecular mechanisms in the development of diabetic vascular complications. Diabetes 1996;45:S105–S108.
   PubMed Web of Science ®Google Scholar
• Giugliano D, Ceriello A, Paolisso G. Oxidative stress and diabetic vascular complications. Diabetes care 1996;19: 257–267.
   PubMed Web of Science ®Google Scholar
• Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, et al. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. PloS one 2008;3:e2849.
   PubMed Web of Science ®Google Scholar
• Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010;107:1058–1070.
   PubMed Web of Science ®Google Scholar
• Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999;48:1–9.
   PubMed Web of Science ®Google Scholar