Brain imaging in methamphetamine-treated mice using a nitroxide contrast agent for EPR imaging of the redox status and a gadolinium contrast agent for MRI observation of blood–brain barrier function

References

• Halpin LE, Collins SA, Yamamoto BK. Neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine. Life Sci 2014;97:37–44.
   PubMed Web of Science ®Google Scholar
• Silverstein PS, Shah A, Gupte R, Liu X, Piepho RW, Kumar S, Kumar A. Methamphetamine toxicity and its implications during HIV-1 infection. J Neurovirol 2011;17:401–415.
   PubMed Web of Science ®Google Scholar
• Yamamoto BK, Moszczynska A, Gudelsky GA. Amphetamine toxicities: classical and emerging mechanisms. Ann NY Acad Sci 2010;1187:101–121.
   PubMed Web of Science ®Google Scholar
• Ramkissoon A, Wells PG. Developmental role of nuclear factor E2-related factor 2 in mitigating methamphetamine fetal toxicity and postnatal neurodevelopmental deficits. Free Radic Biol Med 2013;65:620–631.
   PubMed Web of Science ®Google Scholar
• Banerjee A, Zhang X, Manda KR, Banks WA, Ercal N. HIV proteins (gp120 and Tat) and methamphetamine in oxidative stress-induced damage in the brain: potential role of the thiol antioxidant N-acetylcysteine amide. Free Radic Biol Med 2010;48:1388–1398.
   PubMed Web of Science ®Google Scholar
• Escubedo E, Camarasa J, Chipana C, García-Ratés S, Pubill D. Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity; pharmacological implications. Int Rev Neurobiol 2009;88:121–166.
   PubMed Web of Science ®Google Scholar
• Yamamoto BK, Zhu W. The effects of methamphetamine on the production of free radicals and oxidative stress. J Pharmacol Exp Ther 1998;287:107–114.
   PubMed Web of Science ®Google Scholar
• Yamato M, Kudo W, Shiba T, Yamada K, Watanabe T, Utsumi H. Determination of reactive oxygen species associated with the degeneration of dopaminergic neurons during dopamine metabolism. Free Radic Res 2010;44:249–257.
   PubMed Web of Science ®Google Scholar
• Potula R, Hawkins BJ, Cenna JM, Fan S, Dykstra H, Ramirez SH, et al. Methamphetamine causes mitochondrial oxidative damage in human T lymphocytes leading to functional impairment. J Immunol 2010;185:2867–2876.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Loonam TM, Noailles PA, Angulo JA. Comparison of cocaine- and methamphetamine-evoked dopamine and glutamate overflow in somatodendritic and terminal field regions of the rat brain during acute, chronic, and early withdrawal conditions. Ann NY Acad Sci 2001;937:93–120.
   PubMed Web of Science ®Google Scholar
• Dietrich JB. Alteration of blood-brain barrier function by methamphetamine and cocaine. Cell Tissue Res 2009;336: 385–392.
   PubMed Web of Science ®Google Scholar
• O’Shea E, Urrutia A, Green AR, Colado MI. Current preclinical studies on neuroinflammation and changes in blood-brain barrier integrity by MDMA and methamphetamine. Neuropharmacology 2014;87:125–134.
   PubMed Web of Science ®Google Scholar
• Shiba T, Yamato M, Kudo W, Watanabe T, Utsumi H, Yamada K. In vivo imaging of mitochondrial function in methamphetamine-treated rats. Neuroimage 2011;57:866–872.
   PubMed Web of Science ®Google Scholar
• Fujii H, Sato-Akaba H, Kawanishi K, Hirata H. Mapping of redox status in a brain-disease mouse model by three-dimensional EPR imaging. Magn Reson Med 2011;65:295–303.
   PubMed Web of Science ®Google Scholar
• Sato-Akaba H, Fujii H, Hirata H. Development and testing of a CW-EPR apparatus for imaging of short-lifetime nitroxyl radicals in mouse head. J Magn Reson 2008;193:191–198.
   PubMed Web of Science ®Google Scholar
• Kawada Y, Hirata H, Fujii H. Use of multi-coil parallel-gap resonators for co-registration EPR/NMR imaging. J Magn Reson 2007;184:29–38.
   PubMed Web of Science ®Google Scholar
• Fujii HG, Sato-Akaba H, Emoto MC, Itoh K, Ishihara Y, Hirata H. Noninvasive mapping of the redox status in septic mouse by in vivo electron paramagnetic resonance imaging. Magn Reson Imaging 2013;31:130–138.
   PubMed Web of Science ®Google Scholar
• Emoto MC, Sato-Akaba H, Hirata H, Fujii HG. Dynamic changes in the distribution and time course of blood-brain barrier-permeative nitroxides in the mouse head with EPR imaging: visualization of blood flow in a mouse model of ischemia. Free Radic Biol Med 2014;74:222–228.
   PubMed Web of Science ®Google Scholar
• Anderson ME. Determination of glutathione and glutathione disulfide in biological samples. Methods in Enzymology 1985;113:548–555.
   PubMed Web of Science ®Google Scholar
• Sano H, Matsumoto K, Utsumi H. Synthesis and imaging of blood-brain-barrier permeable nitroxyl-probes for free radical reactions in brain of living mice. Biochem Mol Biol Int 1997; 42:641–647.
   PubMedGoogle Scholar
• Quintanilha AT, Packer L. Surface localization of sites of reduction of nitroxide spin-labeled molecules in mitochondria. Proc Natl Acad Sci USA 1997;74:570–574.
   Google Scholar
• Solhi H, Malekirad A, Kazemifar AM, Sharifi F. Oxidative stress and lipid peroxidation in prolonged users of methamphetamine. Drug Metab Lett 2014;7:79–82.
   PubMedGoogle Scholar
• Gluck MR, Moy LY, Jayatilleke E, Hogan KA, Manzino L, Sonsalla PK. Parallel increases in lipid and protein oxidative markers in several mouse brain regions after methamphetamine treatment. J Neurochem 2001;79:152–160.
   PubMed Web of Science ®Google Scholar
• Açikgöz O, Gönenç S, Kayatekin BM, Pekçetin C, Uysal N, Dayi A, et al. The effects of single dose of methamphetamine on lipid peroxidation levels in the rat striatum and prefrontal cortex. Eur Neuropsychopharmacol 2000;10:415–418.
   PubMed Web of Science ®Google Scholar
• Fornstedt B, Bergh I, Rosengren E, Carlsson A. An improved HPLC-electrochemical detection method for measuring brain levels of 5-S-cysteinyldopamine, 5-S-cysteinyl-3,4- dihydroxyphenylalanine, and 5-S-cysteinyl-3,4-dihydroxyphenylacetic acid. J Neurochem 1990;54:578–586.
   PubMed Web of Science ®Google Scholar
• Hasting TG, Lewis DA, Zigmond MJ. Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections. Proc Natl Acad Sci USA 1996;93:1956–1961.
   PubMed Web of Science ®Google Scholar
• Bowyer JF, Ali S. High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus. Synapse 2006;60:521–532.
   PubMed Web of Science ®Google Scholar
• Ramirez SH, Potula R, Fan S, Eidem T, Papugani A, Reichenbach N, et al. Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells. J Cereb Blood Flow Metab 2009;29:1933–1945.
   PubMed Web of Science ®Google Scholar
• Kousik SM, Napier TC, Carvey PM. The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation. Front Pharmacol 2012;3:1–12.
   PubMed Web of Science ®Google Scholar
• Gu Y, Dee CM, Shen J. Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability. Front Biosci 2011;3:1216–1231.
   Google Scholar
• Danjo S, Ishihara Y, Watanabe M, Nakamura Y, Itoh K. Pentylentetrazole-induced loss of blood-brain barrier integrity involves excess nitric oxide generation by neuronal nitric oxide synthase. Brain Res 2013;1530:44–53.
   PubMed Web of Science ®Google Scholar