References
- Lenk H., Muller U, Tanneberger S. Mitozantrone: Mechanism of Action, antitumour activity, pharmacokinetics, efficacy in the treatment of solid tumours and lymphomas, and. toxicity Anticancer Research 1987; 7: 1257–1264
- Pacuicci P. A., Ohnuma T., Cuttner J., et al. Mitozantrone in patients with acute leukaemia in relapse. Cancer Res. 1983; 43: 3919–3922
- Fosse-Abrahamsen Lenner A., Hedenus P., Landys M.K., Noppa H. Mitozantrone in the treatment of patients with non hodgkins lymphoma. Cancer Treat. Rep. 1987; 71: 1209–1212
- Gianni L., Gorden B.J., Meyers C. E. The biochemical basis of anthracycline toxicity and antitumour activity. In Reviews in Biochemical Toxicity, Hodgson and Philpot. Elsevier, New York 1983; vol 5: 1
- Basra J., Wolf C. R., Brown J. R., Patterson L. H. Evidence for human liver mediated free radical formation by doxorubicin and mitozantrone. Anti-Cancer Drug Design 1985; 1: 45–52
- Soule H. D., Vazquez J., Long A., Albert S., Brennan M. A human cell line from a pleural effusion derived from a breast carcinoma. J. Natl. Cancer Inst. 1973; 51: 1409–1416
- Sinha B. K., Katki A. G., Batist G., Cowan K. H., Myers C. E. Adriamycin stimulated hydroxyl radical formation in human breast tumour cells. Biochem. Pharmacol. 1987; 36: 793–796
- Sinha B. K., Katki Batist A. G., Cowan G.K.H., Myers C. E. Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumour cells: implications for the mechanism of action. Biochem. 1987; 26: 3776–7781
- Shpall E. J., Jones R. B., Holland J. F., et al. Intensive single agent mitozantrone for metastatic breast cancer.J. Natl, Cancer Inst. 1988; 80: 204–208
- Islam S. A., Neidle S., Gandecha B. M., Partridge M., Patterson L. H., Brown J. R. Comparative computer graphics and solution studies of the DNA interaction of substituted anthraquin-ones based on doxorubicin and mitozantrone. J. Med. Chem. 1985; 28: 857
- Graham M. A., Newell D. R., Butler J., Hoey B., Patterson L. H. The effect of the anthra-pyrazole antitumour agent C1941 on rat liver microsome and cytochrome P-450 reductase mediated free radical processes. Biochem. Pharmacol. 1987; 36: 3345–3351
- Fisher G. R., Patterson L. H. Generation of free radicals by doxorubicin in MCF-7 human breast cancer cells. J. Pharmac. Pharmncol. 1988; 39: 28P, (suppl.)
- Kharasch E. D., Novak R. F. Bis(alkylamino)anthracenedione antineoplastic activation by NADPH-cytochrome P-450 reductase and NADPH-dehydrogenase: diminished activity relative to anthracyclines. Arch. Biochem. Biophys. 1983; 224: 682
- Basra J. A study of free radical formation in liver and heart tissue by alkylaminoanthraquinones based on mitozantrone and doxorubicin. Ph.D Thesis, CNAA. Leicester Polytechnic 1986
- Kharasch E. D., Novak R. F. Arch. Biochem. Biophys. 1983; 224: 682