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Free Radical Research Communications Volume 9, 1990 - Issue 3-6
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Original Article

Superoxide Reaction with Nitroxides

Amram Samuni Molecular Biology, Hebrew University Medical School, Jerusalem, Israel
,
C. Murali Krishna Radiation Oncology Branch, Clinical Oncology Program, Division of Cancer Treatment, NCI, National Institutes of Health, Bethesda, MD, 20892, USA
,
James B. Mitchell Radiation Oncology Branch, Clinical Oncology Program, Division of Cancer Treatment, NCI, National Institutes of Health, Bethesda, MD, 20892, USA
,
Christi R. Collins Radiation Oncology Branch, Clinical Oncology Program, Division of Cancer Treatment, NCI, National Institutes of Health, Bethesda, MD, 20892, USA
&
Angelo Russo Radiation Oncology Branch, Clinical Oncology Program, Division of Cancer Treatment, NCI, National Institutes of Health, Bethesda, MD, 20892, USA
Pages 241-249 | Published online: 07 Jul 2009

References

  • Berliner L. J. Spin Labeling: Theory and Applications. Academic Press, NY 1976
  • Berliner L. J. Spin Labeling II: Theory and Applications. Academic Press, NY 1979
  • Morse P. D., II, Swartz H. M. Measurement of intracellular oxygen concentration using the spin label TEMPOL. Mag. Res. Med. 1985; 2: 114–127
  • Mehlhorn R. J., Packer L. Bioenergetic studies of cells with spin probes. Biomembranes and Cell Function, F. A. Kummerow, G. Benga, R. P. Holmes. Ann. N. Y. Acud. Sci., 1983; 414: 190–189
  • Swartz H. M. Interactions between cells and nitroxides and their implications for their uses as biophysical probes and as metabolically responsive contrast agents for in vivo NMR. Bull. Mag. Res. 1986; 8: 172–175
  • Belkin S., Mehlhorn R. J., Hideg K., Hankovsky O., Packer L. Reduction and destruction rates of nitoxide spin probes. Arch. Biochem. Biophy. 1987; 236: 232–243
  • Rosen G. M., kduckman E. J., Hanck K. W. Selective bioreduction of nitroxide by rat liver microsomes. Toxicol. Lett. 1977; 1: 71–74
  • Swartz H. M. Use of nitroxides to measure redox metabolism in cells and tissues. J. Chem. Soc., Faraday Trans. 1987; 1: 83, 191–202
  • Brasch R. C. Methods of contrast enhancement for NMR imaging and potential applications. Work in progress. Radiol. 1983; 147: 781–788
  • Pals M. A., Swartz H. M. Oxygen-dependent metabolism of potential magnetic resonance contrast agents. Invest. Radiol. 1987; 22: 497–501
  • Rigo A., Argese E., Stevanato R., Orsega E. F., Viglino P. A new method of detecting O2-production. Inorg. Chim. Acta 1977; 24: L71–L73
  • Rauckman E. J., Rosen G. M., Kitchell B. B. Superoxide radical as an intermediate in the oxidation of hyroxylamines by mixed function amine oxidase. Mol. Pharmacol. 1979; 15: 131–137
  • Finkelstien E., Rosen G. M., Rauckman E. J. Superoxide-dependent reduction of nitroxide by thiols. Biochem. Biophys. Acta. 1984; 802: 90–98
  • Mehlhorn R. J., Packer L. Electron spin resonance spin destruction methods for radical detection. Meth. Enzymol. 1984; 105: 215–220
  • Blough N. V. Electron paramagnetic resonance measurements of photochemical radical production in humic substances. 1. Effects of O2 and charge on radical scavenging by nitroxides. Environ. Sci. Technol. 1988; 22: 77–82
  • Floyd R. A. Hydroxyl free-radical spin-adducts in rat brain synaptosomes: observations on the reduction of the nitroxide. Biochem. Biophy. Acta. 1983; 756: 204–216
  • Mason R. P. Spin trapping free radical metabolities of toxic chemicals. Spin Labeling in Pharmacology, J. L. Holzman. Academic Press, NY 1984; 87–129
  • Rosen G. M., Finkelstien E., Rauckman E. J. A method for the detection of superoxide in biological systems. Arch. Biochem. Biophys. 1982; 215: 367–378
  • Samuni A., Krishna C. M., Riesz P., Finkelstien E., Russo A. Superoxide reaction with nitroxide spin-adducts. Free Rad. Bid. Med. 1989; 6: 141–148
  • Samuni A., Krishna C. M., Riesz P., Finkelstein E., Russo A. Nitroxide spin label: A novel metal-free low molecular weight superoxide dismutase mimic. J. Biol. Chem. 1988; 263: 17921–17924
  • Janzen E. G. A critical review of spin trapping in biological systems. “Free Radicals in Biology”, W. A. Prior. Academic Press, NY 1980; Vol. IV: 115–154
  • Samuni A., Black C. D. V., Krishna C. M., Malech H. L., Bernstein E. F., Russo A. Hydroxyl radical production by stimulated neutrophils reappraised. J. Biol. Chem. 1988; 263: 13797–13801
  • Fridovich I. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J. Biol. Chem. 1970; 245: 4053–4057
  • Samuni A., Ahn M., Krishna C. M., Mitchell J. B., Russo A. SOD-like activity of 5-membered ring nitroxide spin labels. In “Antioxidants in Therapy and Preventive Medicine”, E. Emerit, C. Auclair, L. Packer. Plenum Press, NY, (in press).
  • Gyllenhammar H. Lucigenin chemiluminescence in the assessment of neutrophil superoxide production. J. Immunol. Meth. 1987; 97: 209–213
  • Hiraishi H., Terano A., Ota S-I., Ivey K. J., Sugimoto T. Oxygen metabolite-induced cytotoxicity to cultured rat gastric mucosal cells. Am. J. Physiol. 1987; 253: G40–G48
  • Gaffney B. J. The chemistry of spin labels. In Spin Labeling: Theory and application, L. J. Berliner. Academic Press, NY 1976; 183–238

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