References
- Bollag W., Grunberg E. Tumour inhibiting effects of new class of cytotoxic agents: methylhydrazine. Experientia 1963; 19: 130–131
- Martz G., D'Alessandrim A., Keel H.J., Bollag W. Preliminary clinical results with a new anti-tumour agent Ro 4–6467 (NSV-77213). Cancer Chemotherapy Reports 1963; 33: 5–14
- DeVita V.T., Serpick A.A., Charbone P.P. Combination chemotherapy in the treatment of advanced Hodgkin's desease. Annals of Intermed Medicine 1970; 72: 881–895
- Nelson S.D., Mitchell J.R., Timbrell J.A., Snodgrass W.R., Corcoran G.G. Isoniazid and iproniazid: activation of metabolite to toxic intermediates in man and rat. Science 1976; 193: 901–903
- Kreis W. Metabolism of an antineoplastic methylhydrazine derivative in a P815 mouse neoplasm. Cancer Research 1970; 30: 82–89
- Weinkam R.J., Shiba D.A. Metabolic activation of procarbazine. Life Science 1978; 22: 937–946
- Dunn D.L., Lubert R.A., Prough R.A. Oxidative metabolism of n-isoproply-α-(2-methylhydraZion)-p-toluamide hydrochloride (procarbazine) by rat liver microsomes. Cancer Re search 1979; 39: 4555–4563
- Weibkin P., Prough R.A. Oxidative metabolism of N-isopropyl-(2-methylazo)-p-tolua-mide (azoprocarbazine) by rodent liver microsomes. Cancer Research 1980; 40: 394–3529
- Nelson S.D., Mitchell J.R., Snodgrass W.R., Timbrell J.A. Hepatotoxicity and metabolism of diiproniazid and isopropylhydrazine. Journal of Pharmacological Experimental Therapapy 1978; 206: 574–585
- Sinha B.K., Motten A.G. Oxidative metabolism of hydralazine: evidence for nitrogen centered radical formation. Biochemical and Biophysical Research Communication 1982; 105: 1044–1051
- Sinha B.K., Patterson M.A. Free radical metabolism of hydralazine. Binding and degrad ation of nucleic acids. Biochemical Pharmacology 1983; 32: 3279–284
- Sinha B.K. Enzymatic activation of hydrazine derivatives. A spin-trapping study. Journal of Biological Chemistry 1983; 258: 796–801
- Sinha B.K. Metabolic activation of procarbazine: evidence for carbon-centered free radical intermediates. Biochemical Pharmacology 1984; 33: 2777–2781
- Kalyanaraman B., Sinha B.K. Free radical-mediated activation of hydrazine derivatives. Environmental Health Perspective 1985; 64: 179–184
- Sinha B.K. Activation of hydrazine derivatives to free radicals in the perfused rat liver: a spin-trapping study. Biochimica et Biophysica Acta 1987; 924: 261–269
- Kaur H., Leung K.H.W., Perkins M.J. A water-soluble nitrosoaromatic spin trap. Journal of the Chemical Saciety 1981; 142–143
- Athar M., Mukhtar H., Bickers D.R., Khan I.U., Kalyanaraman B. Evidence for the metabolism of tumor promoter organic hydroperoxides into free radicals by human carcinoma skin keratinocytes: an ESR-spin trapping study. Carcinogenesis 1989; 10: 1499–1503
- Haim N., Nemec J., Roman J., Sinha B.K. In vitro metabolism of etoposide (VP–16–213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins,. Biochemical Pharmacology 1987; 36: 527–536