Hydroxyl Radicals are Generated by Hepatic Microsomes During Nadph Oxidation: Relationship to Ethanol Metabolism

References

• Keilin D., Hartree E.F. Properties of catalase. Catalysis of coupled oxidation of alcohols. Biochemical Journal 1945; 39: 93–298
   Google Scholar
• Boveris A., Oshino N., Chance B. The cellular production of hydrogen peroxide. Biochemical Journal 1972; 128: 617–630
   PubMed Web of Science ®Google Scholar
• Zahlten R.N., Nejtek M.E., Jacobson J.C. Ethanol metabolism in guinea pigs: In vivo ethanol elimination alcohol dehydrogenase distribution, and subcellular localization of acetaldehyde dehydrogenase in liver. Archives of Biochemistry and Biophysics 1981; 207: 371–379
   Google Scholar
• Orme-Johnson W.H., Ziegler D.M. Alcohol mixed function oxidase activity of mammalian liver microsomes. Biochemical and Biophysical Research Communications 1965; 2178: 78–82
   Google Scholar
• Lieber C.S., DeCarli L.M. Hepatic microsomal ethanol-oxidizing system: in vitro charac-teristics and adaptive properties in vivo. Journal of Biological Chemistry 1970; 254: 2505–2512
   Google Scholar
• Thurman R.G., Ley H.G., Scholz R. Hepatic microsomal ethanol oxidation: hydrogen peroxide formation and the role of catalase. European Journal of Biochemistry 1972; 25: 420–430
   PubMedGoogle Scholar
• Miwa G.T., Levin W., Thomas P.E., Lu A.Y.H. The direct oxidation of ethanol by catalase-and alcohol dehydrogenase-free reconstituted system containing cytochrom P-450. Archive of Biochemistry and Biophysics 1978; 187: 464–475
   PubMed Web of Science ®Google Scholar
• Koop D.R., Morgan E.T., Tarr G.E., Coon M.J. Purification and characterization of a unique isozyme of cytochrome P450 from liver microsomes of ethanol-treated rabbits. Journal of Biological Chemistry 1982; 257: 8472–8480
   PubMed Web of Science ®Google Scholar
• Cederbaum A.I., Dicker E., Cohen E. Role of hydroxyl radicals in microsomal oxidation of alcohols. Advances in Experimental Medicine and Biology 1980; 132: 1–10
   Google Scholar
• Cederbaum A.I. Microsomal generation of hydroxyl radicals: its role in microsomal ethanol oxidizing system (MEOS) activity and requirement for iron. Annals of the New York Academy of Sciences 1987; 492: 35–49
   PubMed Web of Science ®Google Scholar
• Puntarulo S., Cederbaum A.I. Effect of oxygen concentration on microsomal oxidation of ethanol and generation of oxygen radicals. Biochemical Journal 1988; 251: 787–794
   PubMed Web of Science ®Google Scholar
• Ingelman-Sundberg M., Hagbjörk A.L. On the significance of the cytochrome P-450-dependent hydroxyl radical-mediated oxygenation mechanism. Xenobiotica 1982; 12: 673–686
   PubMed Web of Science ®Google Scholar
• Ingleman-Sundberg M., Johansson I. Mechanism of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochromes P-450. Journal of Biological Chemistry 1984; 259: 6447–6458
   PubMedGoogle Scholar
• Ekström G., Cronholm T., Ingelman-Sundberg M. Hydroxyl-radical production and ethanol oxidation by liver microsomes isolated from ethanol-treated rats. Biochemical Journal 1986; 233: 755–761
   PubMed Web of Science ®Google Scholar
• Albano E., Tomasi A., Goria-Gatti L., Poli G., Vannini V., Dianzani M.U. Free radical metabolism of alcohols by rat liver microsomes. Free Radical Research Communications 1987; 3: 243–249
   PubMedGoogle Scholar
• Albano E., Tomasi A., Goria-Gatti L., Dianzani M.U. Spin trapping of free radical species produced during the microsomal metabolism of ethanol. Chemico-Biological Interactions 1988; 65: 223–234
   PubMed Web of Science ®Google Scholar
• Reinke L.A., Lai E.K., DuBose C.M., McCay P.B. Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: correlation with radical formation in vitro. Proceedings of the National Academy of Sciences USA 1987; 84: 9223–9227
   PubMed Web of Science ®Google Scholar
• Reinke L.A., Rau J.M., McCay P.B. Possible roles of free radicals in alcoholic tissue damage. Free Radical Research Communications 1990; 9: 205–211
   PubMed Web of Science ®Google Scholar
• Lai C.-S., Piette L.H. Spin-trapping studies of hydroxyl radical production involved in lipid peroxidation. Archives of Biochemistry and Biophysics 1978; 190: 27–38
   PubMed Web of Science ®Google Scholar
• Saprin A.N., Piette L.H. Spin Trapping and its application in the study of lipid peroxidation and free radical production with liver microsomes. Archives of Biochemistry and Biophysics 1977; 180: 480–492
   PubMed Web of Science ®Google Scholar
• Lai C.-S., Piette L.H. Hydroxyl radical production involved in lipid peroxidation of rat liver microsomes. Biochemical and Biophysical Research Communications 1977; 78: 51–59
   PubMed Web of Science ®Google Scholar
• Terano A., Hiraishi H., Ota S., Shiga J., Sugimoto T. Role of superoxide and hydroxyl radicals in rat gastric mucosal injury induced by ethanol. Gastroenterology Japan 1989; 24: 488–493
   PubMedGoogle Scholar
• Nordmann R., Ribiere C., Rouach H. Involvement of oxygen free radicals in the metabolism and toxicity of ethanol. Progress in Clincial and Biological Research 1987; 241: 201–213
   Google Scholar
• Heim W.G., Appleman D., Pyfrom H.T. Effects of 3-amino-2, 3,4-triazole (AT) on catalase and other compounds. American Journal of Physiology 1956; 186: 19–23
   PubMedGoogle Scholar
• McCay P.B., Lai E.K., Poyer J.L., DuBose C.M., Janzen E.G. Oxygen-and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro. Journal of Biological Chemistry 1984; 259: 2135–2143
   PubMed Web of Science ®Google Scholar
• Buettner G. R. In the absence of catalytic metals ascorbate does not autoxidize at pH 7: ascorbate as a test for catalytic metals. Journal of Biochemical and Biophysical Methods 1988; 16: 27–40
   PubMedGoogle Scholar
• Thomas C.E., Aust S.D. Rat Liver Microsomal NADPH-dependent release of iron from ferritin and liped peroxidation. Free Radicals in Biology and Medicine 1984; 1: 293–300
   Google Scholar
• Gornall A.G., Bardawill C.J., David M.M. Determination of serum proteins by means of biuret reaction. Journal of Biological Chemistry 1991; 177: 751–766
   Google Scholar
• Beers R.F., Jr., Sizer I.W. A spectrophotometric method for measuring the breakdwon of hydrogen peroxide by catalase. Journal of Biological Chemistry 1951; 195: 133–140
   Web of Science ®Google Scholar
• Kok D'A., Wild F. Serum iron determination. Journal of Clinical Pathology 1960; 13: 214–245
   Google Scholar
• Kalyanaraman B., Janzen E.G., Mason R.P. Spin trapping of the azidyl radical in azide/catalase/H202 and various azide/peroxidase/H202 peroxidizing systems. Journal of Biological Chemistry 1985; 260: 4003–1006
   PubMed Web of Science ®Google Scholar
• Minnotti G. Adriamycin-dependent release of iron from microsomal membranes. Archives of Biochemistry and Biophysics 1989; 268: 398–403
   Google Scholar
• Janzen E.G., Nutter D.E., Jr., Davis E.R., Blackburn B.J., Poyer J.L., McCay P.B. On spin trapping hydroxyl and hydroperoxyl radicals. Canadian Journal of Chemistry 1978; 56: 2237–2242
   Web of Science ®Google Scholar
• Finkelstein E., Rosen G.M., Rauckman E.J. Spin trapping of superoxide and hydroxyl radical: practical aspects. Archives of Biochemistry and Biophysics 1980; 200: 1–16
   PubMed Web of Science ®Google Scholar