Human Cytochrome P450′ are Pro-oxidants in Iron/Ascorbate-Initiated Microsomal Lipid Peroxidation

References

• Johnson I. T., Williamson G., Musk S. R.R. Anticarcinogenic factors in plant foods. a new class of nutrients?. Nutrition Research Reviews 1994; 7: 1–30
   PubMedGoogle Scholar
• Minotti G. tert-Butyl hydroperoxide-dependent microsomal release of iron and lipid peroxidation. Archives of Biochemistry and Biophysics 1989; 273: 144–147
   PubMed Web of Science ®Google Scholar
• Bast A., Haenen G.R. M.M. Cytochrome P450 and glutathione: What is the significance of their inkrrelationship in lipid peroxidation?. Trends in Biochemical Sciences 1984; 9: 510–513
   Web of Science ®Google Scholar
• Koster J. F., Slee R. G. Lipid peroxidation of rat liver microsomes. Biochimica et Biophysica Acta 1980; 620: 489–499
   PubMed Web of Science ®Google Scholar
• Buc-Calderon P., Roberfroid M. Inhibition of rat liver microsomal lipid peroxidation by N-acyldehydroalanines: an in vitro comparative study. Archives of Biochemistry and Biophysics 1989; 273: 339–346
   PubMed Web of Science ®Google Scholar
• Svingen B. A., Buege J. A., O'Neal F.O., Aust S. D. The mechanism of NADPH-dependent lipid peroxidation. Journal of Biological Chemistry 1979; 254: 5892–5899
   PubMed Web of Science ®Google Scholar
• Sevanian A., Nordenbrand K., Kim E., Ernster L., Hochstein P. Microsomal lipid peroxidation: the role of NADPH-cytochrome P450 reductase and cytochrome P450. Free Radical Biology and Medicine 1990; 8: 145–152
   PubMed Web of Science ®Google Scholar
• Eksbom G., Ingelman-Sundberg M. Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450 (P-450 IIE1). Biochemical Pharmacology 1989; 38: 1313–1319
   PubMed Web of Science ®Google Scholar
• Ohmori S., Misaizu T., Nakamura T., Takano N., Kitagawa H., Kitada M. Differential role of lipid peroxidation between rat P450 1A1 and P4so 1A2. Biochemical Pharmacology 1993; 46: 55–60
   PubMed Web of Science ®Google Scholar
• Crespi C. L., Langenbach R., Penman B. W. Human cell lines derived from AHH-1 TK +/- human lymphoblasts genetically engineered for expression of cytochromes P450. Toxicology 1993; 82: 89–104
   PubMed Web of Science ®Google Scholar
• Crespi C. L., Penman B. W., Gonzalez F. J., Gelboin H. V., Galvin M., Langenbach R. Genetic toxicology using human cell lines expressing human P450. Biochemical Society Transactions 1993; 21: 1023–1028
   PubMed Web of Science ®Google Scholar
• Lambert N. Isolation of microsomes. Protein Methods: A Practical Approach, E. L.V. Harris, S. Angal. IRL Press, Oxford 1989; 101–108
   Google Scholar
• Burke M. D., Mayer R. T. Ethoxyresorufm: direct assay of a microsomal O-dealkylation which is preferentially inducible by 3-methlycholanthrene. Drug Metabolism Disposition 1974; 2: 583–588
   PubMed Web of Science ®Google Scholar
• Waxman D. J., Ko A., Walsh C. Regioselectivity and stereospecificity of androgen hydroxylations catalysed by cytochrome P450 isozymes purified from phenobarbital-induced rat liver. Journal of Biological Chemistry 1983; 258: 11937–11943
   PubMed Web of Science ®Google Scholar
• Lambert N., Freedman R. B. The latency of rat liver microsomal protein disulphide isomerase. Biochemical Journal 1985; 228: 615–635
   PubMed Web of Science ®Google Scholar
• Smith P. K., Krohn R. I., Hermanson G. T., Mallia A. K., Gartner F. H., Provenzano M. D., Fujimoto E. K., Goeke N. M., Olson B. J., Klenk D. C. Measurement of protein using bicinchoninic acid. Analytical Biochemistry 1985; 150: 76–85
   PubMed Web of Science ®Google Scholar
• Buege J. A., Aust S. D. Microsomal lipid peroxidation. Methods in Enzymology 1978; 30: 302–310
   Google Scholar
• Afanas'ev I.B., Dorozhko A. I., Polozova N. I., Kuprianova N. S., Brodskii A. V., Ostrachovitch E. A., Korkina L. G. Is superoxide an initiator of microsomal lipid peroxidation?. Archives of Biochemistry and Biophysics 1993; 302: 200–205
   PubMed Web of Science ®Google Scholar
• Itoh F., Horie T., Awazu S. Fluorescence emitted from microsomal membranes by lipid peroxidation. Archives of Biochemistry and Biophysics 1988; 264: 184–191
   PubMed Web of Science ®Google Scholar
• Hammond H., Higashi T., Tateishi N., Hanatani M., Sakamoto Y. Lipid peroxidation in the liver of carcinogen-resistant rats. Biochimica et Biophysica Acta 1990; 1045: 96–106
   Google Scholar
• Crespi C. L., Penman B. W., Leakey J. A.E., Arlotto M. P., Stark A., Parkinson A., Turner T., Steimel D. T., Rudo K., Davies R. L., Langenbach R. Human cytochrome P450 IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparisons to nitrosamine activation by human cytochrome P450IIE1. Carcinogenesis 1990; 11: 1293–1300
   PubMed Web of Science ®Google Scholar
• Muindi J. F., Young C. W. Lipid hydroperoxides greatly increase the rate of oxidative catabolism of alltrans-retinoic acid by human cell culture microsomes genetically enriched in specified cytochrome P450 isoforms. Cancer Research 1993; 53: 1226–1229
   PubMed Web of Science ®Google Scholar
• Toole K. The membrane relationship of microsomal nucleoside diphosphatase. International Journal of Biochemistry 1982; 14: 941–947
   PubMedGoogle Scholar
• Beach D. C., Giroux E. Inhibition of lipid peroxidation promoted by iron (III) and ascorbate. Archives of Biochemistry and Biophysics 1992; 297: 258–264
   PubMed Web of Science ®Google Scholar
• Miller D. M., Aust S. D. Studies of ascorbate-dependent, iron catalysed lipid peroxidation. Archives of Biochemistry and Biophysics 1989; 271: 113–119
   PubMed Web of Science ®Google Scholar
• Ursini F., Maiorino M., Valente M., Ferri L., Gregolin C. Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative damage and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides. Biochimica et Biophysica Acta 1982; 710: 197–211
   PubMed Web of Science ®Google Scholar
• McCay P. B., Brueggemann G., Lai E. K., Powell S. R. Evidence that a-tocopherol functions cyclically to quench free radicals in hepatic microsomes. Annals of the New York Academy of Science 1989; 570: 32–45
   PubMed Web of Science ®Google Scholar
• Thomas P. D., Poznansky M. J. Lipid peroxidation inactivates rat liver microsomal glycerol-3-phosphate acyltransferase. The Journal of Biological Chemistry 1990; 265: 2684–2691
   PubMed Web of Science ®Google Scholar
• Morehouse L. A., Aust S. D. Reconstituted microsomal lipid peroxidation: ADP-Fe3+-dependent peroxidation of phospholipid vesicles containing NADPH-cytochrome P450 reductase and cytochrome P450. Free Radical Biology and Medicine 1988; 4: 269–277
   PubMed Web of Science ®Google Scholar
• Garcia-Agundez J. A., Luengo A., Benitez J. Aminopyrine N-demethylase activity in human liver microsomes. Clinical Pharmacology Theory 1990; 48: 490–495
   PubMed Web of Science ®Google Scholar