13
Views
20
CrossRef citations to date
0
Altmetric
Original Article

Expression of BCL-2 Inhibits Cellular Radical Generation

, , , , &
Pages 205-212 | Received 10 Apr 1995, Published online: 07 Jul 2009

References

  • Tsujimoto Y., Finger L., Yunis L., Nowell P., Croce C. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 1984; 226: 1097–1099
  • Mah S. P., Zhong L. T., Lin Y., Roghani A., Edwards R. H., Bredesen D. E. The protooncogene bcl-2 inhibits apoptosis in PC12 cells. Journal of Neurochemistry 1993; 60: 1183–1186
  • Zhong L. T., Sarafian T. A., Kane D. J., Charles A., Mah S., Edwards R. H., Bredesen D. E. Bcl-2 inhibits death of central neural cells induced by multiple agents. Proceedings of the National Academy of Science of the United States of America 1993; 90: 4533–4537
  • Zhong L. T., Kane D. J., Bredesen D. E. Bcl-2 blocks glutamate toxicity in neural cell lines. Molecular Brain Research 1993; 19: 353–355
  • Kane D. J., Sarafian T. A., Anton R., Hahn H., Gralla E. B., Valentine J. S., Ord T., Bredesen D. E. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 1993; 262: 1274–1277
  • Hockenbery D. M., Nunez G., Milliman C., Schreiber R., Korsmeyer S. J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990; 34: 334–336
  • Martinou J. C., Dubois-Dauphin M., Staple J. K., Rodriguez I., Frankowski H., Missotten M., Albertini P., Talabot D., Catsicas S., Pietra C. Overexpression of Bcl-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 1994; 13: 1017–1030
  • Garcia I., Martinou I., Tsujimoto Y., Martinou J. C. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 1992; 258: 302–304
  • Kane D. J., Ord T., Anton R., Bredesen D. E. Expression of bcl-2 inhibits necrotic neural cell death. Journal of Neuroscience Research 1995; 40: 269–275
  • Hockenbery D. M., Oltvai Z. N., Yin X. M., Milliman C. L., Korsmeyer S. J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241–251
  • Pierce G. B., Parchment R. E., Lewellyn A. L. Hydrogen peroxide as a mediator of programmed cell death in the blastocyst. Differentiation 1991; 46: 181–186
  • Sarafian T. A., Bredesen D. E. Is apoptosis mediated by reactive oxygen species?. Free Radical Research 1994; 21: 1–8
  • Stier A., Sackmann E. Spin labels as enzyme substrates. heterogenous lipid distribution in liver microsomal membranes. Biochimica et Biophysica Acta 1973; 311: 400–408
  • Floyd R. A. Hydroxyl free-radical spin-adduct in rat brain synaptosomes. Observation on the reduction of nitroxide. Biochimica et Biophysica Acta 1983; 756: 204–216
  • Finkelstein E., Rosen G. M., Rauckman E. Spin trapping of superoxide and hydroxyl radicals: practical aspects. Archives of Biochemistry and Biophysics 1980; 200: l–16
  • Finkelstein E., Rosen G.M. Use of spin traps in biological systems. Adv Free Radicals Biology and Medicine 1985; 1: 345–375
  • Boesterling B., Trudell J. R. Spin trap evidence for production of superoxide radical anions by purified NADPH-cytochrome P-450 reductase. Biochemical and Biophysical Research Communications 1981; 98: 569–575
  • Trudell J. R. Ethyl acetate extraction of spin trapped free radicals: a reevaluation. Free Radical Biology and Medicine 1987; 3: 133–136
  • Hicks M., Gebicki J. M. Rate constants for reaction of hydroxyl radicals with Tris, Tricine and Hepes buffers. FEBS 1986; 199: 92–94
  • Yim M. B., Chock P. B., Stadtman E. R. Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide. Proceedings of the National Academy of Science of the United States of America 1990; 87: 5006–5010
  • Mottley C., Connor H. D., Mason R. P. [17O] oxygen hyperfine structure for the hydroxyl and superoxide radical adducts of the spin traps DMM), PBN and 4-POBN. Biochemical and Biophysical Research Communications 1986; 141: 622428
  • Britigan B. E., Coffman T. J., Buettner G. R. Spin trapping evidence for the lack of significant hydroxyl radical production during the respiration burst of human phagocytes using a spin adduct resistant to superoxidemediated destruction. Journal of Biological Chemistry 1990; 265: 2650–2656
  • Shimizu S., Eguchi Y., Kosaka H., Kamiike W., Matsuda H., Tsujimoto Y. Prevention of hypoxia-induced cell death by Bcl-2 and BC1-xl. Nature 1995; 374: 811–813
  • Jacobson M. D., Raff M. C. Programmmi cell death and Bcl-2 protection in very low oxygen. Nature 1995; 374: 814–816
  • Fenton H. J.H. Oxidation of tartaric acid in the presence of iron. Journal of the Chemical Society 1894; 65: 899–903

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.