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Original Article

Liposomes Containing α-Tocopherol and Ascorbate are Protected from an External Oxidant Stress

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Pages 373-379 | Received 29 Jul 1996, Published online: 07 Jul 2009

References

  • Doba T., Burton G. W., Ingold K. U. Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon peroxidation of aqueous multilamellar phospholipid liposomes. Biochimica et Biophysica Acta 1985; 835: 298–303
  • Scarpa M., Rigo A., Maiorino M., Ursini F., Gregolin C. Formation of α-tocopherol radical and recycling of α-tocopherol by ascorbate during peroxidation of phosphatidylcholine liposomes. An electron paramagnetic resonance study. Biochimica et Biopliysica Acta 1984; 801: 215–219
  • Leung H.-W., Vang M. J., Mavis R. D. The cooperative interaction between vitamin E and vitamin C in suppression of peroxidation of membrane phospho-lipids. Biochimica et Biophysica Acta 1981; 664: 266–272
  • Niki E., Kawakami A., Yamamoto Y., Kamiya Y. Oxidation of lipids. VIII. Synergistic lnhibition of oxidation of phosphatidylcholine liposome in aqueous dispersion by vitamin E and vitamin C. Bulletin of the Cliemical Society of Japan 1985; 58: 1971–1975
  • Jialal I., Vega G. L., Grundy S. M. Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein. Atherosclerosis 1990; 82: 185–191
  • Retsky K. L., Freeman M. W., Frei B. Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti-rather than prooxidant activity of vitamin C in the presence of transition metal ions. Journal of Biological Chemistry 1993; 268: 1304–1309
  • Buettner G. R. The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. Archives of Biochemistry and Biophysics 1993; 300: 535–543
  • Pick U. Liposomes with a large trapping capacity prepared by freezing and thawing of sonicated phospho-lipid mixtures. Archives of Biochemistry and Biophysics 1981; 212: 186–194
  • Futami A., Hurt E., Hauska G. Vectorial redox reactions of physiological quinones. I. Requirement of a minimum length of the isoprenoid side chain. Biochimca et Biophysica Acta 1979; 547: 583–596
  • Baldwin S. A., Baldwin J. M., Lienhard G. E. Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation. Biochemistry 1982; 21: 3836–3842
  • Folch J., Lees M., Stanley G. H. Sloane. A simple method for the isolation and purification of total lipi-des from animal tissues. Journal of Biological Chemistry 1956; 226: 497–509
  • May J. M., Qu Z. C., Morrow J. D. Interaction of ascorbate and α-tocopherol in resealed human erythrocyte ghosts—Transmembrane electron transfer and protection from lipid peroxidation. Journal of Biological Chemistry 1996; 271: 10577–10582
  • Avron M., Shavit N. A sensitive and simple method for determination of ferrocyanide. Analytical Biochemistry 1963; 6: 549–554
  • May J. M., Qu Z.-C., Whitesell R. R. Ascorbate is the major electron donor for a transmembrane oxi-doreductase of human erythrocytes. Biochimica et Biophysica Acta 1995; 1238: 127–136
  • Wolff S. P. Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods in Enzymology 1994; 233: 182–189
  • Ames B. N. Assay of inorganic phosphate, total phosphate and phosphatases. Methods in Enzymology 1966; 8: 115–118
  • Kagan V. E., Serbinova E. A., Bakalova R. A., Stoytchev T. S., Erin A. N., Prilipko L. L., Evstigneeva R. P. Mechanisms of stabilization of biomembranes by alpha-tocopherol. The role of the hydrocarbon chain in the inhibition of lipid peroxidation. Biochemical Pharmacology 1990; 40: 2403–2413
  • Ilani A., Krakover T. Diffusion- and reaction rate-limited redox processes mediated by quinones through bilayer lipid membranes. Biophysical Journal 1987; 51: 161–167
  • Niki E. Antioxidants in relation to lipid peroxidation. Chemistry and Physics of lipids 1987; 44: 227–253

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