Will the ‘Good Fairies’ Please Prove to us that Vitamin E Lessens Human Degenerative Disease?

References

• Evans H. M. The pioneer history of vitamin E. Vitamins and Hormones 1962; 20: 379–387
   Web of Science ®Google Scholar
• Evans H. M., Burr G. O., Althausen T. Memoirs University of California 1927; 8: 1–23
   Google Scholar
• Evans H. M., Bishop K. S. On the existence of a hitherto unrecognized dietary factor essential for reproduction. Science 1922; 56: 650–651
   PubMedGoogle Scholar
• Evans H. M., Bishop K. S. Existence of a hitherto unknown factor essential for reproduction. Journal of the American Medical Association 1923; 81: 889–892
   Google Scholar
• Fernholtz E. Journal of the American Chemical Society 1937; 59: 1154–1155
   Google Scholar
• Fernholtz E. Journal of the American Chemical Society 1938; 60: 700–705
   Google Scholar
• Karrer P., Fritzsche H., Ringier B. H., Snlomon A. Helvetica Chimica Acta 1938; 21: 820–825
   Google Scholar
• Slater E. C., Rudney H., Bouman J., Links J. The possible role of α-tocopherol in the respiratory chain III. The tocopherol and ubiquinone content of heartmuscle preparation. Biochimica et Biophysica Acta 1960; 47: 197–514
   Google Scholar
• Dam H. Influence of antioxidants and redox substances on signs of vitamin E deficiency. Pharmacological Reviews 1957; 9: 1–16
   PubMed Web of Science ®Google Scholar
• Tappel A. L. Vitamin E as the biological lipid antioxidant. Vitamins and Hormones 1962; 20: 237–253
   Web of Science ®Google Scholar
• Choshal A. K., Recknagel R. O. Liver damage caused by carbon tetrachloride. Life Scicence 1967; 4: 121–128
   Google Scholar
• Comporti M. Lipid peroxidation and cellular damage in toxic liver injury. Laboratory Investigation 1985; 53: 599–614
   PubMed Web of Science ®Google Scholar
• Slater T. F., Sawyer B. C. The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum. Biochemical Journal 1971; 123: 815–821
   PubMed Web of Science ®Google Scholar
• Slater T. F., Sawyer B. C. The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents. Biochemical Journal 1971; 123: 823–828
   PubMed Web of Science ®Google Scholar
• Slater T. F., Sawyer B. C. The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro. Biochonical Journal 1971; 123: 805–814
   PubMed Web of Science ®Google Scholar
• Green J., Bunyan J., Cawthorne M. A., Diplock A. T. Vitamin E and hepatotoxic agents.1. Carbon tetrachloride and lipid peroxidation in the rat. British Journal of Nutritional 1969; 23: 297–307
   PubMed Web of Science ®Google Scholar
• Bunyan J., Cawthorne M. A., Diplock A. T., Green J. Vitamin E and hepatotoxic agents.2.Lipid peroxidation and poisoning with orotic acid, ethanol and thioacetamide in rats. British Journal of Nutrition 1969; 23: 309–317
   PubMed Web of Science ®Google Scholar
• Rice-Evans C. A. Formation of free radicals and mechanisms of action in normal biochemical processes and pathological states, in Free Radical Damage and Its Control, C. A. Rice-Evans, R. H. Burdons. Elsevier, Amsterdam, London, New York and London 1994; 129–151
   Google Scholar
• Babior B. New England Journal of Medicine 1978; 298: 659–668
   PubMed Web of Science ®Google Scholar
• Cross A., Jones O. G. Review. Enzymic meclianisms of superoxide production. Biochimica et Biophysica Acta 1991; 1057: 281–291
   PubMed Web of Science ®Google Scholar
• Moncada S., Palmer R. M. J., Higgs E. A. Relationship between prostacyclin and nitric oxide in the thrombotic process. Thrombosis Ressearch 1990; 11: 3–13
   Google Scholar
• Halliwell B., Gutteridge J. M. C. Free Radicals in Biology and Midicine. Clarendon Press, Oxford 1989; 2nd ed.: 513
   Google Scholar
• Diplock A. T. The role of antioxidant nutrients in defence systems. Encylopaedia of Food Science, Food Technology and Nutriton, R. Macrae, R. Robinson, M. Sadlers. Academic Press, London 1992; 211–216
   Google Scholar
• Ames B. N., Shingenaga M. K., Park E. M. DNA damage by endogenous oxidants as a cancer of aging and cancer in Oxidation Damage and Repair: Chemical, Biological and Medical Aspects, K. J. A. Davis. Pergarnon, New York 1991; 181–187
   Google Scholar
• Halliwell B., Aruoma O. I. DNA and Free Radicals. Ellis Horwood, New York, London 1993; 332
   Google Scholar
• Ames B. N., Shigenaga M. K. Oxidants are a major contributor to cancer and aging, in DNA and Free Radicals, B. Halliwell, O. I. Aruoma. Ellis Horwood, New York and London, 1–15
   Google Scholar
• Marnett L., Hurd H. K., Hollenstein M. K., Levin D. E., Esterbauer H., Ames 8. H. Naturally occurring carbonyl compounds and nutagens in Salmonella tester strain TA 104. Mutation Research 1985; 148: 25–34
   PubMed Web of Science ®Google Scholar
• Esterbauer H., Schaur R. J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and releted aldehydes. Free Radicals in Biology and Medicine 1991; 11: 81–128
   PubMed Web of Science ®Google Scholar
• Dizdaroglu M. Chemistry of free radical damage to DNA and nucleoproteins, in DNA and Free Radicals, B. Halliwell, O. I. Aruoma. Ellis Horwood, New York and London 1993; 19–39
   Google Scholar
• Meneghini R., Martins E. L. Hydrogen peroxide and DA damage, in DNA and Free Radicals, B. Haliwell, O. I. Aruoma. Ellis Horwood, New York and London 1993; 83–93
   Google Scholar
• Thorsten K., Romslo I. Uptake of iron from transferrin by isolated hepatocytes. Biochimica et Biophysic Acta 1984; 804: 200–208
   PubMed Web of Science ®Google Scholar
• Wiseman H., Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochemical Journal 1996; 313: 17–29
   PubMed Web of Science ®Google Scholar
• Cheeseman K. H. Lipid peroxidation and cancer, in DNA and Free Radicals, B. Halliwell, O. I. Aruoma. Ellis Horwood, New York and London 1993; 109–144
   Google Scholar
• Tappel A. L., Dillard C. J. In vivo lipid peroxidation: measurement via exhaled pentane and protection by vitamin E. Federation Proceedings 1981; 40: 174–178
   PubMedGoogle Scholar
• Esterbauer H. Lipid peroxidation products. Formation chemical properties and biological activities. Free Radicals in Liver Injury 1985; 29–47
   Google Scholar
• Esterbauer H., Koller E., Heckenast P., Moser R., Celotto C. Cytotoxic lipid peroxidation products. First Vienna Sliock Forum 1987; 245–252
   Google Scholar
• Bce-Evans C., Bruckdorfer K. R. Free radicals, lipoproteins and cardiovascular dysfunction. Molecular Aspects of Medicine 1992; 13: 1–111
   PubMedGoogle Scholar
• Tappel A. L. Studies of the effects of free radical damage to proteins. Archives of Biochemistry and Biophysics 1955; 54: 266–280
   PubMed Web of Science ®Google Scholar
• Stadtman E. R. Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions. Annual Reviews of Biochemistry 1993; 62: 797–821
   PubMed Web of Science ®Google Scholar
• Stadtman E. R. Protein oxidation and aging. Science 1992; 257: 1220–1224
   PubMed Web of Science ®Google Scholar
• Diplock A. T. Fat soluble vitamins: their biochemistry and applications. Heinemann. 1985; 319
   Google Scholar
• Diplock A. T., Lucy J. A. The biochemical modes of action of vitamin E and selenium: a hypothesis. FEBS Letters 1973; 29: 205–210
   PubMed Web of Science ®Google Scholar
• Diplock A. T. Antioxidants and free radical scavengers, in Free Radical Damage and Its Control, C. A. Rice-Evans, R. H. Burdon. Elsevier, Amsterdam, London, New York and Tokyo 1994; 111–127
   Google Scholar
• Burton G. W., Wronska U., Stone L., Foster D. O., Ingold K. U. Biokinetics of dietary RRR-α-tocopherol in male guinea pigs at three dietary levels of vitamin C and vitamin E. Evidence that vitamin C does not “spare” vitamin E. in vivo. Lipids 1990; 25: 199–210
   PubMed Web of Science ®Google Scholar
• FrucHart J. C., Duriez P. Free radicals and atherosclerosis, in Free Radical Damage and Its Control, C. A. Rice-Evans, R. H. Burdon. Elsevier, Amsterdam, London, New York and Tokyo 1944; 253–276
   Google Scholar
• Kalyanaraman B., Konorev E. A., Joseph J., Baker J. E. Radical generation and detection in myocardial injury, in Free Radical Damage and Its Control, C. A. Rice-Evans, R. H. Burdon. Elsevier, Amserdam, London, New York and Tokyo 1994; 329–355
   Google Scholar
• Burdon R. Free Radicals and cell proliferation. Free Radical Damage an Its control, C. A. Rice-Evans, R. H. Burdons. Elsevier, Amsterdam, London, New York and Tokyo 1994; 153–183
   Google Scholar
• Jacques P. F., Chylack L. T. Epidemiological evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. American Journal of Clinical Nutrition 1991; 53: 352S-355S
   PubMedGoogle Scholar
• Knekt P., Heliovaara M., Rissanen A., Aromaa A., Aaran R. K. Serum antioxidant vitamins and risk of cataract. British Medical Journal 1992; 305(6866)1392–4
   PubMed Web of Science ®Google Scholar
• Taylor A. Cataract: relationship between nutrition and oxidation. Journal of the American College of Nutrition 1993; 12(2)138–46
   PubMed Web of Science ®Google Scholar
• Finer N. M., Peters K. L., Schindler R. F., Grant G. D. Vitamin E and retrolental fibroplasia, in Biology of Vitamin E, R. Porter, J. Whelan. Pitman, London 1985; 147–164
   Google Scholar
• Hitner H., Kretzer F. L., Rudolph A. J. Prevention and managment of retrolental fibroplasia. Hospital Practice 1984; 19: 85–99
   Web of Science ®Google Scholar
• Johnson L. Retrolental fibroplasia: a new look at an unsolved problem. Hospital Practice 1981; 109–121
   Web of Science ®Google Scholar
• Parsons B. J. Chemical aspects of free radical reactions in connective tissue, in Free Radical Damage and Its Control, C. A. Rice-Evans, R. H. Burdon. Elsevier, Amsterdam, London, New York and Tokyo 1994; 277–296
   Google Scholar
• Winyard P. G., Morris C. J., Winrow V. R., Zaidi M., Blake D. R. Free radical pathways in the inflammatory response, in Free Radical Damage and Its Control, C, A. Rice-Evans, R. H. Burdon. Elsevie, Amsterdam, London, New York and Tokyo 1994; 357–379
   Google Scholar
• Hall E. D. Free radicals in central nervous system injury, in Free Radical Damage and Its Control, C. A. Rice-Evans, R. H. Burdon. Elsevier, Amsterdam, London, New York and Tokyo 1994; 213–234
   Google Scholar
• Morrero R., Marnett L. J. The role of organic peroxyl radicals in carcinogenesis, in DNA and Free Radicals, B. Halliwell, O. I. Aruoma. Ellis Horwood, New York and London 1993; 145–161
   Google Scholar
• Barrera G., Mauro C. D., Maraca R., Ferrero D., Cavalli G., Fazio V. M., Pnradisi L., Dianzani M. U. Experimental Cellfular Research 1991; 197: 148–152
   PubMed Web of Science ®Google Scholar
• Slater T. F., Benedetto C., Cheeseman K. H., Collins M., Davies M. J., Flatman S., Hayashi M., Hurst J. S., McDonald-Gibson R. G., Morgan A., Nigam S., Proudfoot K. Free Radicals, Cell Damage and Disease, C. Rice-Evans. Reichlieu Press, London 1986; 57–72
   Google Scholar
• Steinbrecher U. P. Oxidation of human low density lipoprotein results in derivatisation of lysine residues of apolipoprotein β by lipid peroxidation decomposition products. Journal of Biological Chemistry 1987; 262: 3603–3608
   PubMed Web of Science ®Google Scholar
• Esterbauer H., Rotheneder M., Striegl G., Waeg G., Ashy A., Sattler W., Jurgens G. Vitamin E and other lipopliylic antioxidants protect LDL against oxidation. Fat Science and Technology 1989; 91: 316–324
   Google Scholar
• Wissler R. W. Atherosclerosis Reviews, R. Paoletti, A. M. Gottos. Raven Press, New York 1978; 213–247
   Google Scholar
• Blankenhorn D. H., Nessim S. A., Jolinson R. D., Samniarco M. E., Azen S. P., Cashin-Hemphill L. Journal of American Medical Association 1987; 257: 3233
   PubMed Web of Science ®Google Scholar
• Block G., Menkes M. Ascorbic acid in cancer prevention, in Diet and cancer prevention: investigating the role of micronutrients, T. E. Moon, M. S. Micozzis. Marcel Dekker, New York 1989; 341–388
   Google Scholar
• Block G. Vitamin C and cancer prevention: the epidemiologic evidence. American Journal of Clinical Nutrition 1991; 53: 270S-282S
   PubMedGoogle Scholar
• Ziegler R. G. A review of epidemiologic evidence that carotenoids reduce the risk of cancer. Journal of Nutrition 1989; 119: 116–122
   PubMed Web of Science ®Google Scholar
• Basu T. K., Temple N. J., Hodgson A. M. Vitamin A, beta-carotene and cancer. Progress in Clinical Biological Research 1988; 259: 255–267
   Google Scholar
• Block G., Patterson B., Subar A. Fruit vegetables and cancer prevention: a review of the epidemiological evidence. Nutrition and Cancer 1992; 18: 1–29
   PubMed Web of Science ®Google Scholar
• Ellis N. I., Lloyd B., Lloyd R. S., Clayton B. E. Selenium and vitamin E in relation to risk factors for coronary heart disease. journal of Clincal Pathology 1984; 37: 200–6
   PubMed Web of Science ®Google Scholar
• Cherniauskene R., Margiavichene L. E., Varslikiavichene Z. Z., Gribauskas P. S. Vitamin E and serum lipids in ischemic heart disease (In Russian). Vopr Med Khim 1984; 30: 102–5
   PubMedGoogle Scholar
• Gey K. F. On the antioxidant hypothesis with regard to arteriosclerosis. Bibliotheca Nutritica Dietetica 1986; 37: 53–91
   PubMedGoogle Scholar
• Horwitt M. K., Harvey C. C., Dahm C. H., Searcy M. T. Relationship between tocopherol and serum lipid levels for determination of nutritional adequacy. Annuals of the New York Academy of Sciences 1972; 203: 223–236
   PubMed Web of Science ®Google Scholar
• WHO. World Health Organization. The WHO MONICA Project. World Health Statistics 1989; 42: 27–149
   Google Scholar
• Gey K. F., Puska P., Jordan P., Moser U. K. Inverse correlation between plasma vitahi E and mortality from ischemic heart disease in cross-cultural epidemiology. American Journal of Clinical Nutirion 1991; 53: 326S-334S
   PubMed Web of Science ®Google Scholar
• Riemersma R. A., Wood D. A., Macintyre C. C., Elton R. A., Gey K. F., Oliver M. F. Risk of angina pectoris and plasma concentrations of vitamins A, C, and E, and carotene. Lancet 1991; 337: 1–5
   PubMed Web of Science ®Google Scholar
• Rimm E. B., Stampfer M. J., Ascherio A., Giovannucci E., Colditz G. A., Willett W. C. Vitamin E consumption and the risk of coronary heart disease in men. New England Journal of Medicine 1993; 328: 1450–6
   PubMed Web of Science ®Google Scholar
• Stampfer M. J., Hennekens C. H., Manson I. E., Colditz C. A., Rosner B., Willett W. C. Vitamin E consumption and the risk of coronary disease in women. New. England Journal of Medicine 1993; 328: 7444–9
   Google Scholar
• Salonen J. T., Yla-Herttuala S., Yamaninto R., Butler S., Korpela H., Salonen R., Nyyssonen K., Palinski W., Witztum J. L. Autoantibody against oxidised LDL and progression of carotid atherosclerosis. The Lancet 1992; 339: 883–888
   PubMed Web of Science ®Google Scholar
• Haberland M. E., Fong D., Cheng L. Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidaemic rabbits. Science 1988; 241: 215–218
   PubMed Web of Science ®Google Scholar
• Boyd H. C., Gown A. M., Wolfbauer G., Chait A. Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanbe heritable hyperlipidaemic rabbit. American Journal of Pathology 1989; 135: 815–825
   PubMed Web of Science ®Google Scholar
• Palinski W., Rosenfeld M. E., Yla-Herrtuala S. Low density lipoprotein undergoes oxidative modification in vivo. Proceedings of the National Academy of Science USA 1989; 86: 1372–1376
   PubMed Web of Science ®Google Scholar
• Gaziano J. M., Manson J. E., Riclker P. M., Burling J. E., Hennekens C. E. Beta carotene therapy for chronic stable angina. Circulation 1990; 82: 201
   Web of Science ®Google Scholar
• Stephens N. G., I'arsons A., Schofield P. M., Kelly F., Cheeseman K., Mitchinsnn M. J. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996; 347: 781–6
   PubMed Web of Science ®Google Scholar
• Cey K. F., Moser U. K., Jordan P., Stahelin H. B., Eichholzer M., Ludin E. Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C. American Journal of Clinical Nutrition 1993; 57: 787S-797S
   PubMedGoogle Scholar
• Steinberg D. Antioxidant vitamins and coronary heart disease [editorial; comment]. New England Journal of Medicine 1993; 328: 1487–9
   PubMed Web of Science ®Google Scholar