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Original Article

Ascorbic Acid Inhibits Lipid Peroxidation but Enhances DNA Damage in Rat Liver Nuclei Incubated with Iron Ions

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Pages 585-592 | Received 18 Nov 1996, Published online: 07 Jul 2009

References

  • Cerutti P., Larsson R., Krupitza G., Muehlmatter D., Crawford D., Amstad P. Pathophysiological mechanisms of active oxygen. Mutation Research 1989; 214: 81–88
  • Shigenaga M. K., Ames B. Assays for 8-hydroxy-2′-deoxyguanosine: a biomarker of in vivo oxidative DNA damage. Free Rodical Biology. & Medicine 1991; 10: 211–216
  • Halliwell B., Aruoma O. I. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS. Letters 1991; 281: 9–19
  • Halliwell B., Dizdaroglu M. The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radical Research Communicastions 1992; 16: 75–87
  • Fraga C. G., Tappel A. L. Damage to DNA concurrent with lipid peroxidation in rat liver slices. Biovhemical Journal 1988; 252: 893–896
  • Sahu S. C., Gray G. C. Interactions of flavonoicls, trace metals, and oxygen: nuclear DNA damage ancl lipid peroxidation induced by myricetin. Cancer Letters 1993; 70: 73–79
  • Shires T. K. Iron-induced DNA damage ancl synthesis in isolated rat liver nuclei. Biochemical Journal 1982; 205: 321–329
  • Hruszkewycz A. M. Evidence for mitochondrial DNA damage by lipid peroxidation. Biochemical Biophysical Research Communications 1988; 153: 191–197
  • Hruszkewycz A. M., Bergtold D. S. The 8-hydroxyguanine content of isolated mitochondria increases with lipid peroxidation. Mutation Research 1990; 244: 123–128
  • Zastawny T. H., Altman S. A., Randers-Eichhorn L., Madurawe R., Lumpkin J. A., Dizdaroglu M., Rao G. DNA base modifications and membrane clamagc in cultured mammalian cells treated with iron ions. Free Radical Biology & Medicine 1995; 18: 1013–1022
  • Sai K., Takagi A., Umemura T., Hasegawa R., Kurokawa Y. Relation of 8-hydroxydeoxyguanosinc formation in rat kidney to lipid peroxidation, glutathione level and relative organ weight after a single administration of potassium bromide. Japanese Journal of Cancer Research 1991; 82: 165–169
  • Halliwell B. Drug antioxidant effects. Drugs 1991; 42: 569–605
  • Halliwell B. Oxidation of low-density lipoproteins: questions of initiation, propagation, and the effect of antioxidants. American Journal of Clinical Nutrition 1995; 61: 670S-677S, (suppl)
  • Cheeseman K. H. Lipid peroxidation and cancer. DNA and Free Radicals, B. Halliwell, O. I. Aruoma. Ellis Horwood, New York 1993; 109–144
  • Fiala E. S., Conaway C. C., Mathis J. E. Oxidative DNA and RNA damage in the livers of Sprague-Dawley Rats treated with the hepatocarcinogen 2-nitropropane. Cancer Research 1989; 49: 5518–5522
  • Aust S. D., Miller D. M., Samokyszyn V. M. Iron redox reaction and lipid peroxidation. Methods in Enzymology 1990; 186: 457–463
  • Gupta R. C. Nonrandom binding of the carcinogenN-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proceedings of the National Academy of Science of the United States of American 1984; 81: 6943–6947
  • Shigenaga M. K., Park J-W., Cundy K. C., Gimeno C. J., Ames B. N. In vivo oxidative DNA damage: measurement of 8-hydroxy-2′-deoxyguanosine in DNA and urine by high-performance liquid chromatography with electrochemical detection. Methods in Enzymology 1990; 186: 521–530
  • van der Zee J., van Steveninck J., Koster J. F., Dubbelman T. M. A. R. Inhibition of enzymes and oxidative damage of red blood cells induced by t-butylhy-droperoxide-derived radicals. Biochemica et Biophysica Acta 1989; 980: 175–180
  • Huang C-H., Hutlin H. O., Jafar S. S. Some aspects of Fe2+-catalyzed oxidation of fish sarcoplasmic reticular lipid. Journal of Agricultural and Food Chemistry 1993; 41: 1886–1892
  • Esterbauer H., Gebicki J., Puhl H., Lurgens G. the role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radical Biology & Medicine 1992; 13: 341–390
  • Halliwell B., Gutteridge J. M. C. Free Radical in Biology & Medicine. Clarendon Press, Oxford 1989; 2nd
  • Reif D. W. Ferritin as a source of iron for oxidative damage. Free Radical Biology & Medicine 1992; 12: 417–427
  • Kasai H., Nishimura S. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agent. Nucleic acid Resenrch 1984; 12: 2137–2145
  • Wissler R. W. Atherosclerosis Reviews, R. Paoletti, A. M. Gottos. Raven Press, New York 1978; 213–247
  • Blankenhorn D. H., Nessim S. A., Johnson R. D., Sanimarco M. E., Azen S. P., Cashin-Hemphill L. Journal of American Medical Association 1987; 257: 3233
  • Block G., Menkes M. Ascorbic acid in cancer prevention, in Diet and cancer prevention: investigating the role of micromutrients, T. E. Moon, M. S. Micozzis. Marcel Dekker, New York 1989; 341–388
  • Block G. Vitamin C and cancer prevention: the epidemiologic evidence. American Journal of Clinical Nutrition 1991; 53: 270S-282S
  • Ziegler R. G. A review of epidemiologic evidence that carotenoids reduce the risk of cancer. Journal of Nutrition 1989; 119: 116–122
  • Basu T. K., Temple N. J., Hodgson A. M. Vitamin A, beta-carotene and cancer. Progress in Clinical Biological Ressearch 1988; 259: 255–267
  • Block G., Patterson B., Subar A. Fruit vegetables and cancer prevention: a review of the epidemiological evidence. Nutrition and Cancer 1992; 18: 1–29
  • Ellis N. I., Lloyd B., Lloyd R. S., Clayton 8. E. Selenium and vitamin E in relation to risk factors for coronary heart disease. Journal of Clinical Pathology 1984; 37: 200–6
  • Cherniauskene R., Margiavichene L. E., Varsh-Kiavichene Z. Z., Gribauskas P. S. Vitamin E and serum lipids in ischemic heart disease (In Russian). Vopr Med Khim 1984; 30: 102–5
  • Gey K. F. On the antioxidant hypothesis with regard to arteriosclerosis. Bibliotheca Nutritica Diestetica 1986; 37: 53–91
  • Horwitt M. K., Harvey C. C., Dahm C. H., Searcy M. T. Relationship between tocopherol and serum lipid levels for determination of nutritional adequacy. Annals of the New York Academy of Sciences 1972; 203: 223–236
  • WHO. World Health Organization. The WHO MONICA Project. World Health Statistics 1989; 42: 27–149
  • Gey K. F., Puska P., Jordan P., Moser U. K. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. American Journal of Clinical Nutrition 1991; 53: 326S-334S
  • Riemersma R. A., Wood D. A., Macintyre C. C., Elton R. A., Gey K. F., Oliver M. F. Risk of angina pectoris and plasma concentrations of vitamins A, C, and E, and carotene. Lancet 1991; 337: 1–5
  • Rinim E. B., Stampfer M. J., Ascherio A., Giovannucci E., Colditz G. A., Willett W. C. Vitamin E consumption and the risk of coronary heart disease in men. New England Journal of Medicine 1993; 328: 1450–6
  • Stampfer M. J., Hennekens C. H., Manson J. E., Colditz G. A., Rosner B., Willett W. C. Vitamin E consumption and the risk of coronary disease in women. New England Journal of Medicine 1993; 328: 1444–9
  • Salonen J. T., Yla-Herttuala S., Yamamoto R., Butler S., Korpela H., Salonen R., Nyyssonen K., Palinski W., Witztum J. L. Autoantibody against oxidised LDL and progression of carotid atherosclerosis. The Lancet 1992; 339: 883–888
  • Haberland M. E., Fong D., Cheng L. Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidaemic rabbits. Science 1988; 241: 215–218
  • Boyd H. C., Gown A. M., Wolfbauer G., Chait A. Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanbe heritable hyperlipidaemic rabbit. American Journal of Pathology 1989; 135: 815–825
  • Palinski W., Rosenfeld M. E., Yla-Herrtuala S. Low density lipoprotein undergoes oxidative modification in vivo. Proceedings of the National Academy of Science USA 1989; 86: 1372–1376
  • Gaziano J. M., Manson J. E., Fidker P. M., Burling J. E., Hennekens C. E. Beta carotene therapy for chronic stable angina. Circulation 1990; 82: 201
  • Stephens N. G., Parsons A., Schofield P. M., Kelly F., Cheeseinan K., Mitchinson M. J. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996; 347: 781–6
  • Gey K. F., Moser U. K., Jordan P., Stahelin H. B., Eicliholzer M., Ludin E. Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C. American Journal of Clinical Nutrition 1993; 57: 787S-797S
  • Steinberg D. Antioxidant vitamins and coronary heart disease [editorial; comment]. New England Journal of Medicine 1993; 328: 1487–9

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