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Original Articles

Optimization of PEGylated nanoemulsions for improved pharmacokinetics of BCS class II compounds

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Pages 467-474 | Received 12 Aug 2013, Accepted 21 Nov 2013, Published online: 18 Dec 2013

References

  • Amin K, Dannenfelser RM. (2006). In vitro hemolysis: guidance for the pharmaceutical scientists. J Pharm Sci 95:1173–6
  • Backmann N, Kappeler N, Braun T, et al. (2010). Sensing surface PEGylation with microcantilevers. Beilstein J Nanotechnol 1:3–13
  • Chaudhari KR, Ukawala M, Manjappa AS, et al. (2012). Opsonization, biodistribution, cellular uptake and apoptosis study of PEGylated PBCA nanoparticle as potential drug delivery carrier. Pharm Res 29:53–68
  • Constantinides PP, Chaubal MV, Shorr R. (2008). Advances in lipid nanodispersions for parenteral drug delivery and targeting. Adv Drug Deliv Rev 60:757–67
  • Devalapally H, Silchenko S, Zhou F, et al. (2013). Evaluation of a nanoemulsion formulation strategy for oral bioavailability enhancement of danazol in rats and dogs. J Pharm Sci 102:3808–15
  • Dudrick SJ. (2009). History of parenteral nutrition. J Am Coll Nutr 28:243–51
  • Erlich L, Yu D, Pallister DA, et al. (1999). Relative bioavailability of danazol in dogs from liquid-filled hard gelatin capsules. Int J Pharm 179:49–53
  • Fischer D, Osburg B, Petersen H, et al. (2004). Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynycleotides in mice. Drug Metab Dispos 32:983–92
  • Ganta S, Devalapally H, Baguley B, et al. (2008). Microfluidic preparation of chlorambucil nanoemulsion formulation and evaluation of cytotoxicity and pro-apoptotic activity in tumor cells. J Biomed Nanotechnol 4:165–73
  • Hong RL, Huang CJ, Tseng YL, et al. (1999). Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial?. Clin Cancer Res 5:3645–52
  • Ichikawa H, Watanabe T, Tokumitsu H, Fukumori Y. (2007). Formulation consideration of gadolinium lipid nanoemulsion for intravenous delivery to tumors in neutron-capture therapy. Curr Drug Deliv 4:131–40
  • Jiang SP, He SN, Li YL, et al. (2013). Preparation and characteristics of lipid nanoemulsion formulations loaded with doxorubicin. Int J Nanomed 8:3141–50
  • Klibanov AL, Maruyama K, Torchilin VP, Huang L. (1990). Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett 268:235–7
  • Krzyzaniak JF, Alvarez Núñez FA, Raymond DM, Yalkowsky SH. (1997). Lysis of human red blood cells. 4. Comparison of in vitro and in vivo hemolysis data. J Pharm Sci 86:1215–17
  • Liu F, Liu D. (1995). Long-circulating emulsions (oil-in-water) as carriers for lipophilic drugs. Pharm Res 12:1060–4
  • Moghimi SM, Hunter AC, Murray JC. (2001). Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev 53:283–318
  • Owen DE III, Peppas NA. (2006). Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int J Pharm 307:93–102
  • Roser M, Fischer D, Kissel T. (1998). Surface-modified biodegradable albumin nano- and microspheres. II. Effect of surface charges on in vitro phagocytosis and biodistribution in rats. Eur J Pharm Biopharm 46:255–63
  • Shah P, Bhalodia D, Shelat P. (2010). Nanoemulsion: a pharmaceutical review. Syst Rev Pharm 1:24–32
  • Shan X, Liu C, Yuan Y, et al. (2009). In vitro macrophage uptake and in vivo biodistribution of long-circulation nanoparticles with poly(ethylene-glycol)-modified PLA (BAB type) triblock copolymer. Colloids Surf B Biointerfaces 72:303–11
  • Sheng Y, Yuan Y, Liu C, et al. (2009). In vitro macrophage uptake and in vivo biodistribution of PLA-PEG nanoparticles loaded with hemoglobin as blood substitutes: effect of PEG content. J Mater Sci Mater Med 20:1881–91
  • Shibuya-Fujiwara N, Hirayama F, Ogata Y, et al. (2001). Phagocytosis in vitro of polyethylene glycol-modified liposome-encapsulated hemoglobin by human peripheral blood monocytes plus macrophages through scavenger receptors. Life Sci 70:291–300
  • Singh M, Ravin LJ. (1986). Parenteral emulsions as drug carrier system. J Parenter Sci Technol 40:34–41
  • Strickley RG. (2004). Solubilizing excipients in oral and injectable formulations. Pharm Res 21:201–30
  • Torchilin VP. (2005). Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 4:145–60
  • Van Vlerken LE, Vyas TK, Amiji M. (2007). Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery. Pharm Res 24:1405–14
  • Wang M, Thanou M. (2010). Targeting nanoparticles to cancer. Pharm Res 62:90–9
  • Woodburn K, Chang CK, Lee S, et al. (1994). Biodistribution and PDT efficacy of a ketochlorin photosensitizer as a function of the delivery vehicle. Photochem Photobiol 60:154–9
  • Yamaoka T, Tabata Y, Ikada Y. (1994). Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice. J Pharm Sci 83:601–6
  • Yang A, Liu W, Li Z, et al. (2010). Influence of polyethyleneglycol modification on phagocytic uptake of polymeric nanoparticles mediated by immunoglobulin G and complement activation. J Nanosci Nanotechnol 10:622–8

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