Advanced search
Publication Cover
Drug Delivery Volume 22, 2015 - Issue 3
Submit an article Journal homepage
1,820
Views
48
CrossRef citations to date
0
Altmetric
Research Article

Treatment of glioma by cisplatin-loaded nanogels conjugated with monoclonal antibodies against Cx43 and BSAT1

Vladimir P. BaklaushevDepartment of Medicinal Nanobiotechnology, Pirogov Russian State Medical University, Moscow, Russia, ;Department of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia, Correspondence[email protected]
,
Natalia N. NukolovaDepartment of Medicinal Nanobiotechnology, Pirogov Russian State Medical University, Moscow, Russia, ;Department of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia, ;Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russia,
,
Alexander S. KhalanskyResearch Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia, and
,
Olga I. GurinaDepartment of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia,
,
Gaukhar M. YusubalievaDepartment of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia,
,
Nadejhda Ph. GrinenkoDepartment of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia,
,
Ilya L. GubskiyDepartment of Medicinal Nanobiotechnology, Pirogov Russian State Medical University, Moscow, Russia,
,
Pavel A. MelnikovDepartment of Medicinal Nanobiotechnology, Pirogov Russian State Medical University, Moscow, Russia,
,
Karina Sh. KardashovaDepartment of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia,
,
Alexander V. KabanovDepartment of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russia, ;UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC, USA
&
Vladimir P. ChekhoninDepartment of Medicinal Nanobiotechnology, Pirogov Russian State Medical University, Moscow, Russia, ;Department of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia,
show all
Pages 276-285 | Received 30 Oct 2013, Accepted 13 Dec 2013, Published online: 17 Jan 2014

References

  • Baklaushev VP, Gurina OI, Yusubalieva GM, et al. (2009). Immunofluorescent analysis of connexin-43 using monoclonal antibodies to its extracellular domain. Bull Exp Biol Med 148:725–30
  • Baklaushev VP, Kardashova KSh, Gurina OI, et al. (2012). Cloning and expression of brain-specific anion transporter BSAT1 and isolation of monoclonal antibodies to its extracellular fragment. Bull Exp Biol Med 152:734–8
  • Baklaushev VP, Yusubalieva GM, Tsitrin EB, et al. (2011). Visualization of connexin 43-positive cells of glioma and the periglioma zone by means of intravenously injected monoclonal antibodies. Drug Deliv 18:331–7
  • Bates DC, Sin WC, Aftab Q, Naus CC. (2007). Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus. Glia 55:1554–64
  • Chekhonin VP, Baklaushev VP, Yusubalieva GM, et al. (2012). Targeted delivery of liposomal nanocontainers to the peritumoral zone of glioma by means of monoclonal antibodies against GFAP and the extracellular loop of Cx43. Nanomedicine 8:63–70
  • Hartmann JT, Lipp HP. (2003). Toxicity of platinum compounds. Expert Opin Pharmacother 4:889–901
  • Kabanov AV, Vinogradov SV. (2009). Nanogels as pharmaceutical carriers: finite networks of infinite capabilities. Angew Chem Int Ed Engl 48:5418–29
  • Li JY, Boado RJ, Pardridge WM. (2004). Blood-brain barrier genomics. J Cereb Blood Flow Metab 21:61–8
  • Nukolova NV, Oberoi HS, Cohen SM, et al. (2011a). Folate-decorated nanogels for targeted therapy of ovarian cancer. Biomaterials 32:5417–26
  • Nukolova NV, Yang Z, Kim JO, et al. (2011b). Polyelectrolyte nanogels decorated with monoclonal antibody for targeted drug delivery. React Funct Polym 71:315–23
  • Oberoi HS, Laquer FC, Marky LA, et al. (2011). Core cross-linked block ionomer micelles as pH-responsive carriers for cis-diamminedichloroplatinum(II). J Control Release 153:64–72
  • Oberoi HS, Nukolova NV, Laquer FC, et al. (2012). Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice. Int J Nanomed 7:2557–71
  • Oliveira R, Christov C, Guillamo JS, et al. (2005). Contribution of gap junctional communication between tumor cells and astroglia to the invasion of the brain parenchyma by human glioblastomas. BMC Cell Biol 6:7
  • Peer D, Karp JM, Hong S, et al. (2007). Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2:751–60
  • Prochnow N, Dermietzel R. (2008). Connexons and cell adhesion: a romantic phase. Histochem Cell Biol 130:71–7
  • Steiniger SC, Kreuter J, Khalansky AS, et al. (2004). Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. Int J Cancer 109:759–67
  • Sugiyama D, Kusuhara H, Taniguchi H, et al. (2003). Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine. J Biol Chem 278):43489–95
  • Wohlfart S, Khalansky AS, Bernreuther C, et al. (2011). Treatment of glioblastoma with poly(isohexyl cyanoacrylate) nanoparticles. Int J Pharm 415:244–51
  • Yusubalieva GM, Baklaushev VP, Gurina OI, et al. (2012). Antitumor effects of monoclonal antibodies to connexin 43 extracellular fragment in induced low-differentiated glioma. Bull Exp Biol Med 153:163–9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.