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Original Paper

Characterization and evaluation of self-nanoemulsifying sustained-release pellet formulation of ziprasidone with enhanced bioavailability and no food effect

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Pages 2163-2172 | Received 07 Jul 2014, Accepted 29 Jul 2014, Published online: 22 Aug 2014

References

  • Balakumar K, Raghavan CV, Selvan NT, et al. (2013). Self nanoemulsifying drug delivery system (SNEDDS) of Rosuvastatin calcium: design, formulation, bioavailability and pharmacokinetic evaluation. Colloids Surf B Biointerfaces 112:337–43
  • Basalious EB, Shawky N, Badr-Eldin SM. (2010). SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: developmentand optimization. Int J Pharm 391:203–11
  • Chae GS, Lee JS, Kim SH, et al. (2005). Enhancement of the stability of BCNU using self-emulsifying drug delivery systems (SEDDS) and in vitro antitumor activity of self-emulsified BCNU-loaded PLGA wafer. Int J Pharm 301:6–14
  • Chambin O, Jannin V, Champion D, et al. (2004). Pourcelot, influence of cryogenic grinding on properties of a self-emulsifying formulation. Int J Pharm 278:79–89
  • Citrome L. (2009). Using oral ziprasidone effectively: the food effect and dose-response. Adv Ther 26:739–48
  • Constantinides PP. (1995). Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects. Pharm Res 12:1561–72
  • Dokania S, Joshi AK. (2014). Self-microemulsifying drug delivery system (SMEDDS)-challenges and road ahead. Drug delivery 1–16
  • El-Leithy ES, Ibrahim HK, Sorour RM. (2013). In vitro and in vivo evaluation of indomethacin nanoemulsion as a transdermal delivery system. Drug Deliv 1–8
  • Elnaggar YS, El-Massik MA, Abdallah OY. (2009). Self-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimization. Int J Pharm 380:133–41
  • Fagiolini A, Canas F, Gallhofer B, et al. (2010). Strategies for successful clinical management of schizophrenia with ziprasidone. Expert Opin Pharmacother 11:2199–220
  • Fukumori Y. (1997). Coating of multiparticulates using polymeric dispersions. In: Ghebre-Sellassie I, ed. Multiparticulate oral drug delivery. New York: Marcel Dekker, 79–111
  • Greenberg WM, Citrome, L. (2007). Ziprasidone for schizophrenia and bipolar disorder: a review of the Clinical trials. CNS Drug Rev 13:137–77
  • Gursoy RN, Benita S. (2004). Self-microemulsifying drug delivery systems (SMEDDS) for improved oral delivery of lipophilic drugs. Biomed Pharmacother 58:173–82
  • Harvey PD, Bowie CR. (2005). Ziprasidone: efficacy, tolerability, and emerging data on wide-ranging effectiveness. Expert Opin Pharmacother 6:337–46
  • Khan AW, Kotta S, Ansari SH, et al. (2014). Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: design, characterization, in vitro and in vivo evaluation. Drug Deliv 1–10
  • Kommura TR, Gurley B, Khan MA, Reddy IK. (2001). Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. Int J Pharm 212:233–46
  • Lincoln J, Stewart Mark E, Preskorn Sheldon H. (2010). How sequential studies inform drug development: evaluating the effect of food intake on optimal bioavailability of ziprasidone. J Psychiatr Pract 16:103–14
  • Lu JL, Wang JC, Zhao SX, et al. (2008). Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice. Eur J Pharm Biopharm 69:899–907
  • McCreadie R, Macdonald E, Blacklock C, et al. (1998). Dietary intake of schizophrenic patient in Nithsdale, Scotland: case-control study. BMJ 317:784–5
  • Miceli JJ, Wilner KD, Hansen RA, et al. (2000). Single- and multiple-dose pharmacokinetics of ziprasidone under nonfasting conditions in healthy male volunteers. Br J Clin Pharmacol 49:5S–13S
  • Muller RH, Jacobs C, Kayser O. (2001). Nanosuspensions as particulate drug formulations in therapy rationale for development and what we can expect for the future. Adv Drug Deliv Rev 47:3–19
  • Patel NC, Keck PE. (2006). Ziprasidone: efficacy and safety in patients with bipolar disorder. Expert Rev Neurother 6:1129–38
  • Perkins DO. (2002). Predictors of noncompliance in patients with schizophrenia. J Clin Psychiatr 63:1121–8
  • Porter CJ, Trevaskis NL, Charman WN. (2007). Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov 6:231–48
  • Pouton CW, Porter CJ. (2008). Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies. Adv Drug Deliv Rev 60:625–37
  • Prasad RYV, Puthli SP, Eaimtrakarn S, et al. (2003). Enhanced intestinal absorption of vancomycin with labrasol and D-α-tocopheryl PEG 1000 succinate in rats. Int J Pharm 250:181–90
  • Preskom SH. (2005). Pharmacokinetics and therapeutics of acute intramuscular ziprasidone. Clin Pharmacokinet 44:1117–33
  • Serratoni M, Newton M, Booth S, Clarke A. (2007). Controlled drug release from pellets containing water-insoluble drugs dissolved in a self-emulsifying system. Eur J Pharm Biopharm 65:94–8
  • Setthacheewakul S, Mahattanadul S, Phadoongsombut N, et al. (2010). Development and evaluation of selfmicroemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats. Eur J Pharm Biopharm 76:475–85
  • Siddique S, Khanam J, Bigoniya P. (2010). Development of sustained release capsules containing coated matrix granules of metoprolol tartrate. AAPS Pharm SciTechnol 11:1306–14
  • Singh B, Bandopadhyay S, Kapil R, et al. (2009). Self-emulsifying drug delivery systems (SEDDS): formulation development, characterization, and applications. Crit Rev Ther Drug Carrier Syst 26:427–521
  • Swenson ES, Curatolo WJ. (1992). Means to enhance penetration. Adv Drug Deliv Rev 8:39–42
  • Thombrea AG, Herbig SM, Alderman JA. (2011). Improved ziprasidone formulations with enhanced bioavailability in the fasted state and a reduced food effect. Pharm Res 28:3159–70
  • Thombrea AG, Shah JC, Sagawa K, Caldwell WB. (2012). In vitro and in vivo characterization of amorphous, nanocrystalline, and crystalline ziprasidone formulations. Int J Pharm 428:8–17
  • Wang ZY, Sun J, Wang YJ, et al. (2010). Solid self-microemulsifying nitrendipine pellets: preparation and in vitro/in vivo evaluation. Int J Pharm 383:1–6
  • Wei Y, Ye X, Shang X, Peng X. (2012). Enhanced oral bioavailability of silybin by a supersaturatable self-emulsifying drug delivery system (S-SEDDS). Colloid Surf A: Physicochem Eng Aspects 396:22–8
  • Wu W, Wang Y, Que L. (2006). Enhanced bioavailability of silymarin by selfmicroemulsifying drug delivery system. Eur J Pharm Biopharm 63:288–94
  • Xi J, Chang Q, Chan CK, et al. (2009). Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid. AAPS Pharm Sci Tech 10:172–82
  • Zhang P, Liu Y, Feng N, Xu J. (2008). Preparation and evaluation of self microemulsifiying drug delivery system of oridonin. Int J Pharm 355:269–76
  • Zhang Y, Wang R, Wu J, Shen Q. (2012). Characterization and evaluation of self-microemulsifying sustained-release pellet formulation of puerarin for oral delivery. Int J Pharm 427:337–44

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