Subcutaneously injected ivermectin-loaded mixed micelles: formulation, pharmacokinetics and local irritation study

References

• Aguiar J, Carpena P, Molina-BolıVar J, Carnero Ruiz C. (2003). On the determination of the critical micelle concentration by the pyrene 1: 3 ratio method. J Colloid Interf Sci 258:116–22
   Web of Science ®Google Scholar
• Ali D, Hennessy D. (1996). The effect of level of feed intake on the pharmacokinetic disposition and efficacy of ivermectin in sheep. J Vet Pharmacol Ther 19:89–94
   PubMed Web of Science ®Google Scholar
• Ali M, Afzal M, Verma M, et al. (2013). Improved antifilarial activity of ivermectin in chitosan–alginate nanoparticles against human lymphatic filarial parasite, Brugia malayi. Parasitol Res 112:2933–43
   PubMed Web of Science ®Google Scholar
• Alkan-Onyuksel H, Ramakrishnan S, Chai H-B, Pezzuto JM. (1994). A mixed micellar formulation suitable for the parenteral administration of taxol. Pharmaceut Res 11:206–12
   PubMed Web of Science ®Google Scholar
• Alkan-Onyuksel H, Son K. (1992). Mixed micelles as proliposomes for the solubilization of teniposide. Pharmaceut Res 9:1556–62
   PubMed Web of Science ®Google Scholar
• Alvinerie M, Escudero E, Sutra J-F, et al. (1998). The pharmacokinetics of moxidectin after oral and subcutaneous administration to sheep. Vet Res 29:113–18
   PubMed Web of Science ®Google Scholar
• Amiji MM. (1995). Pyrene fluorescence study of chitosan self-association in aqueous solution. Carbohyd Polym 26:211–13
   Web of Science ®Google Scholar
• Attwood D, Florence A. (1983). Surfactant systems: their chemistry, pharmacy and biology. London: Chapman & Hall
   Google Scholar
• Bassissi F, Lespine A, Alvinerie M. (2006). Assessment of a liposomal formulation of ivermectin in rabbit after a single subcutaneous administration. Parasitol Res 98:244–9
   PubMed Web of Science ®Google Scholar
• Dourmishev A, Serafimova D, Dourmishev L. (1998). Efficacy and tolerance of oral ivermectin in scabies. J Eur Acad Dermatol 11:247–51
   Web of Science ®Google Scholar
• Draize JH, Woodard G, Calvery HO. (1944). Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther 82:377–90
   Web of Science ®Google Scholar
• Duan RL, Sun X, Liu J, et al. (2011). Mixed micelles loaded with silybin-polyene phosphatidylcholine complex improve drug solubility. Acta Pharm Sinic 32:108–15
   Web of Science ®Google Scholar
• Frosch PJ. (1995). Cutaneous irritation. Textbook of contact dermatitis. Berlin, Germany: Springer
   Google Scholar
• González Canga A, Sahag N Prieto AM, Jos Diez Li Bana M, et al. (2009). The pharmacokinetics and metabolism of ivermectin in domestic animal species. Vet J 179:25–37
   PubMed Web of Science ®Google Scholar
• Hammad M, Müller B. (1998a). Increasing drug solubility by means of bile salt–phosphatidylcholine-based mixed micelles. Eur J Pharm Biopharm 46:361–7
   PubMed Web of Science ®Google Scholar
• Hammad M, Müller B. (1998b). Solubility and stability of tetrazepam in mixed micelles. Eur J Pharmaceut Sci 7:49–55
   PubMed Web of Science ®Google Scholar
• Hennessy D. (1997). Modifying the formulation or delivery mechanism to increase the activity of anthelmintic compounds. Vet Parasitol 72:367–90
   PubMed Web of Science ®Google Scholar
• Lazarewicz JW, Pluta R, Salinska E, Puka M. (1989). Beneficial effect of nimodipine on metabolic and functional disturbances in rabbit hippocampus following complete cerebral ischemia. Stroke 20:70–7
   PubMed Web of Science ®Google Scholar
• Leak LV. (1971). Studies on the permeability of lymphatic capillaries. J Cell Biol 50:300–23
   PubMed Web of Science ®Google Scholar
• Lifschitz A, Virkel G, Sallovitz J, et al. (2000). Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle. Vet Parasitol 87:327–38
   PubMed Web of Science ®Google Scholar
• Liu X, Sun Q, Wang H, et al. (2005). Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials 26:109–15
   PubMed Web of Science ®Google Scholar
• Lo P-KA, Fink DW, Williams JB, Blodinger J. (1985). Pharmacokinetic studies of ivermectin: effects of formulation. Vet Res Commun 9:251–68
   PubMed Web of Science ®Google Scholar
• Lo PKA, Williams JB. (1983). Solubilization of ivermectin in water. Google Patents
   Google Scholar
• Luo X, Wang Q, Zhou L, et al. (2010). Study on relationship between Tween-80 contained in injections of Chinese herbal medicine and anaphylactic reactions. Adv Drug Reactions J 12:160–5
   Google Scholar
• Ménard N, Tsapis N, Poirier C, et al. (2012). Drug solubilization and in vitro toxicity evaluation of lipoamino acid surfactants. Int J Pharmaceut 423:312–20
   PubMed Web of Science ®Google Scholar
• Masini E, Planchenault J, Pezziardi F, et al. (1985). Histamine-releasing properties of Polysorbate 80in vitro andin vivo: correlation with its hypotensive action in the dog. Agents Actions 16:470–7
   PubMedGoogle Scholar
• Mazer NA, Benedek GB Carey MC. (1980). Quasielastic light-scattering studies of aqueous biliary lipid systems. Mixed micelle formation in bile salt-lecithin solutions. Biochemistry 19:601–15
   PubMed Web of Science ®Google Scholar
• Moschetta A, Portincasa P, Palasciano G, et al. (2000). Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts. J Lipid Res 41:916–24
   PubMed Web of Science ®Google Scholar
• Narain P, Demaria E, Heuman D. (1998). Lecithin protects against plasma membrane disruption by bile salts. J Surg Res 78:131–6
   PubMed Web of Science ®Google Scholar
• Quagliotto P, Barbero N, Barolo C, et al. (2009). Characterization of monomeric and gemini cationic amphiphilic molecules by fluorescence intensity and anisotropy. Dyes Pigments 82:124–9
   Web of Science ®Google Scholar
• Salvioli G, Gaetti E, Panini R, et al. (1993). Different resistance of mammalian red blood cells to hemolysis by bile salts. Lipids 28:999–1003
   PubMed Web of Science ®Google Scholar
• Son K, Alkan-Onyuksel H. (1996). Physical stability of teniposide in bile salt-egg phosphatidylcholine mixed micelles and liposomes. PDA J Pharm Sci Tech 50:89–93
   PubMedGoogle Scholar
• Song X, Jiang Y, Ren C, et al. (2011). Nimodipine-loaded mixed micelles: formulation, compatibility, pharmacokinetics, and vascular irritability study. Int J Nanomed 7:3689–99
   Web of Science ®Google Scholar
• Steel J. (1993). Pharmacokinetics and metabolism of avermectins in livestock. Vet Parasitol 48:45–57
   PubMed Web of Science ®Google Scholar
• Tagboto S, Townson S. (1996). Onchocerca volvulus and O. lienalis: the microfilaricidal activity of moxidectin compared with that of ivermectin in vitro and in vivo. Ann Tropic Med Parasitol 90:497–505
   PubMed Web of Science ®Google Scholar
• Teelmann K, Schl Ppi B, Sch Pbach M, Kistler A. (1983). Preclinical safety evaluation of intravenously administered mixed micelles. Arzneimittel-Forschung 34:1517–23
   Web of Science ®Google Scholar
• Tompkins J, Stitt L, Ardelli B. (2010). Brugia malayi: in vitro effects of ivermectin and moxidectin on adults and microfilariae. Exper Parasitol 124:394–402
   PubMed Web of Science ®Google Scholar
• Wicks S, Kaye B, Weatherley A, et al. (1993). Effect of formulation on the pharmacokinetics and efficacy of doramectin. Vet Parasitol 49:17–26
   PubMed Web of Science ®Google Scholar
• Zhang, R.-L., Cui, L.-L., Hao, Z.-H, Zhao, Y.-D. 2011. Compare Pharmacokinetics of 5 Different Ivermectin Injection in Rabbit. China Animal Husbandry & Veterinary Medicine, 38(11):188–90
   Google Scholar