Epirubicin loading in poly(butyl cyanoacrylate) nanoparticles manifests via altered intracellular localization and cellular response in cervical carcinoma (HeLa) cells

References

• Amaral JD, Xavier JM, Steer CJ, Rodrigues CM. (2010). The role of p53 in apoptosis. Discov Med 9:145–52
   PubMed Web of Science ®Google Scholar
• Azarmi S, Tao X, Chen H, et al. (2006). Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles. Int J Pharm 319:155–61
   PubMed Web of Science ®Google Scholar
• Bender AR, von Briesen H, Kreuter J, et al. (1996). Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/macrophages in vitro. Antimicrob Agents Chemother 40:1467–71
   PubMed Web of Science ®Google Scholar
• Calero F, Rodriguez-Escudero F, Jimeno J, et al. (1991). Single agent epirubicin in squamous cell cervical cancer. A phase II trial. Acta Oncol 30:325–7
   PubMed Web of Science ®Google Scholar
• Cersosimo RJ, Hong WK. (1986). Epirubicin: a review of the pharmacology, clinical activity, and adverse effects of an adriamycin analogue. J Clin Oncol 4:425–39
   PubMed Web of Science ®Google Scholar
• Chaabane W, User SD, El-Gazzah M, et al. (2012). Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer. Arch Immunol Ther Exp 61:43–58
   PubMed Web of Science ®Google Scholar
• Chumakov PM. (2007). Versatile functions of p53 protein in multicellular organisms. Biochemistry 72:1399–421
   PubMed Web of Science ®Google Scholar
• Davidson MB, Thakkar S, Hix JK, et al. (2004). Pathophysiology, clinical consequences, and treatment of tumor lysis syndrome. Am J Med 116:546–54
   PubMed Web of Science ®Google Scholar
• De Juan BS, von Briesen H, Gelperina SE, Kreuter J. (2006). Cytotoxicity of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles in rat glioma cell lines using different assays. J Drug Target 14:614–22
   PubMed Web of Science ®Google Scholar
• De Smet L, Ceelen W, Remon JP, Vervaet C. (2013). Optimization of drug delivery systems for intraperitoneal therapy to extend the residence time of the chemotherapeutic agent. Sci World J 2013:720858. doi:10.1155/2013/720858
   Web of Science ®Google Scholar
• Edinger AL, Thompson CB. (2004). Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 16:663–9
   PubMed Web of Science ®Google Scholar
• Fang J, Nakamura H, Maeda H. (2010). The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev 63:136–51
   PubMed Web of Science ®Google Scholar
• Faraji AH, Wipf P. (2009). Nanoparticles in cellular drug delivery. Bioorg Med Chem 17:2950–62
   PubMed Web of Science ®Google Scholar
• Ferrandina G, Distefano MG, De Vincenzo R, et al. (2012). Paclitaxel, epirubicin, and cisplatin (TEP) regimen as neoadjuvant treatment in locally advanced cervical cancer: long-term results. Gynecol Oncol 128:518–23
   PubMed Web of Science ®Google Scholar
• Fink SL, Cookson BT. (2005). Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect Immun 73:1907–16
   PubMed Web of Science ®Google Scholar
• Fontana G, Licciardi M, Mansueto S, et al. (2001). Amoxicillin-loaded polyethylcyanoacrylate nanoparticles: influence of PEG coating on the particle size, drug release rate and phagocytic uptake. Biomaterials 22:2857–65
   PubMed Web of Science ®Google Scholar
• Fridman JS, Lowe SW. (2003). Control of apoptosis by p53. Oncogene 22:9030–40
   PubMed Web of Science ®Google Scholar
• Gewirtz DA. (1999). A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 57:727–41
   PubMed Web of Science ®Google Scholar
• Graf A, Mcdowell A, Rades T. (2009). Poly(alkycyanoacrylate) nanoparticles for enhanced delivery of therapeutics-is there real potential? Expert Opin Drug Deliv 6:371–87
   PubMed Web of Science ®Google Scholar
• Grankvist K, Henriksson R. (1987). Doxorubicin and epirubicin iron-induced generation of free radicals in vitro. A comparative study. Biosci Rep 7:653–8
   PubMed Web of Science ®Google Scholar
• Greish K, Nagamitsu A, Fang J, Maeda H. (2005). Copoly(styrene-maleic acid)-pirarubicin micelles: high tumor-targeting efficiency with little toxicity. Bioconjug Chem 16:230–6
   PubMed Web of Science ®Google Scholar
• Greish K, Sawa T, Fang J, et al. (2004). SMA-doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours. J Control Release 97:219–30
   PubMed Web of Science ®Google Scholar
• Juan BSD. (2005). The analysis of doxorubicin-loaded poly(butyl cyanoacrylate) nanoparticles in in vitro glioma models. Chemistry, Biochemistry and Pharmacy. Frankfurt am Main: Johann-Wolfgang-Goethe University
   Google Scholar
• Kamura T, Ushijima K. (2013). Chemotherapy for advanced or recurrent cervical cancer. Taiwan J Obstet Gynecol 52:161–4
   PubMed Web of Science ®Google Scholar
• Kisich K, Gelperina S, Higgins M, et al. (2007). Encapsulation of moxifloxacin within poly (butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis. Int J Pharm 345:154–62
   PubMed Web of Science ®Google Scholar
• Kroemer G, Galluzzi L, Vandenabeele P, et al. (2009). Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 16:3–11
   PubMed Web of Science ®Google Scholar
• Larson N, Greish K, Bauer H, et al. (2011). Synthesis and evaluation of poly(styrene-co-maleic acid) micellar nanocarriers for the delivery of tanespimycin. Int J Pharm 420:111–7
   PubMed Web of Science ®Google Scholar
• Lince F, Bolognesi S, Marchisio DL, et al. (2011). Preparation of poly (MePEGCA-co-HDCA) nanoparticles with confined impinging jets reactor: experimental and modeling study. J Pharm Sci 100:2391–405
   PubMed Web of Science ®Google Scholar
• Mahajan N, Sakarkar D, Manmode A, et al. (2011). Biodegradable nanoparticles for targeted delivery in treatment of ulcerative colitis. Adv Sci Lett 4:349–56
   Web of Science ®Google Scholar
• Mao S, Guo C, Shi Y, Li LC. (2012). Recent advances in polymeric microspheres for parenteral drug delivery–part 2. Expert Opin Drug Deliv 9:1209–23
   PubMed Web of Science ®Google Scholar
• Matteoni R, Kreis TE. (1987). Translocation and clustering of endosomes and lysosomes depends on microtubules. J Cell Biol 105:1253–65
   PubMed Web of Science ®Google Scholar
• Minotti G, Menna P, Salvatorelli E, et al. (2004). Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56:185–229
   PubMed Web of Science ®Google Scholar
• Miyazaki S, Takahashi A, Kubo W, et al. (2003). Poly n-butylcyanoacrylate (PNBCA) nanocapsules as a carrier for NSAIDs: in vitro release and in vivo skin penetration. J Pharm Pharm Sci 6:238–45
   PubMed Web of Science ®Google Scholar
• Nicolas J, Couvreur P. (2009). Synthesis of poly (alkyl cyanoacrylate)-based colloidal nanomedicines. Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:111–27
   PubMed Web of Science ®Google Scholar
• Oowaki H, Matsuda S, Sakai N, et al. (2000). Non-adhesive cyanoacrylate as an embolic material for endovascular neurosurgery. Biomaterials 21:1039–46
   PubMed Web of Science ®Google Scholar
• Ouyang L, Shi Z, Zhao S, et al. (2012). Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif 45:487–98
   PubMed Web of Science ®Google Scholar
• Paudel KR, Rauniar GP, Bhattacharya SK, Das BP. (2008). Recent advancement in drug delivery system. Kathmandu Univ Med J 6:262–7
   PubMedGoogle Scholar
• Pinto-Alphandary H, Andremont A, Couvreur P. (2000). Targeted delivery of antibiotics using liposomes and nanoparticles: research and applications. Int J Antimicrob Agents 13:155–68
   PubMed Web of Science ®Google Scholar
• Plosker GL, Faulds D. (1993). Epirubicin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cancer chemotherapy. Drugs 45:788–856
   PubMed Web of Science ®Google Scholar
• Ramge P, Unger RE, Oltrogge JB, et al. (2000). Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells. Eur J Neurosci 12:1931–40
   PubMed Web of Science ®Google Scholar
• Riedl SJ, Shi Y. (2004). Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5:897–907
   PubMed Web of Science ®Google Scholar
• Schwartz D, Rotter V. (1998). p53-dependent cell cycle control: response to genotoxic stress. Semin Cancer Biol 8:325–36
   PubMed Web of Science ®Google Scholar
• Simeonova M, Ivanova G, Enchev V, et al. (2009). Physicochemical characterization and in vitro behavior of daunorubicin-loaded poly(butylcyanoacrylate) nanoparticles. Acta Biomater 5:2109–21
   PubMed Web of Science ®Google Scholar
• Torchilin V. (2010). Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 63:131–5
   PubMed Web of Science ®Google Scholar
• Tzeng SY, Green JJ. (2013). Therapeutic nanomedicine for brain cancer. Ther Deliv 4:687–704
   PubMedGoogle Scholar
• Uskokovic V. (2013). Entering the era of nanoscience: time to be so small. J Biomed Nanotechnol 9:1441–70
   PubMed Web of Science ®Google Scholar
• Vasir JK, Labhasetwar V. (2007). Biodegradable nanoparticles for cytosolic delivery of therapeutics. Adv Drug Deliv Rev 59:718–28
   PubMed Web of Science ®Google Scholar
• Vats A, Pathak K. (2013). Exploiting microspheres as a therapeutic proficient doer for colon delivery: a review. Expert Opin Drug Deliv 10:545–57
   PubMed Web of Science ®Google Scholar
• Vauthier C, Labarre D, Ponchel G. (2007). Design aspects of poly (alkylcyanoacrylate) nanoparticles for drug delivery. J Drug Target 15:641–63
   PubMed Web of Science ®Google Scholar
• Von Briesen H, Ramge P, Kreuter JR. (2000). Controlled release of antiretroviral drugs. AIDS Rev 2:31–8
   Google Scholar
• Weiss CK, Kohnle MV, Landfester K, et al. (2008). The first step into the brain: uptake of NIO-PBCA nanoparticles by endothelial cells in vitro and in vivo, and direct evidence for their blood-brain barrier permeation. ChemMedChem 3:1395–403
   PubMed Web of Science ®Google Scholar
• World Health Organization. (2013). Human papillomavirus (HPV) and cervical cancer, Fact sheet No. 380, Media Centre, World Health Organization, http://www.who.int/mediacentre/factsheets/fs380/en/
   Google Scholar
• Wohlfart S, Khalansky AS, Bernreuther C, et al. (2011). Treatment of glioblastoma with poly(isohexyl cyanoacrylate) nanoparticles. Int J Pharm 415:244–51
   PubMed Web of Science ®Google Scholar
• Yordanov G. (2012). Poly(alkyl cyanoacrylate) nanoparticles as drug carriers: 33 years later. Bulgarian J Chem 1:61–73
   Google Scholar
• Yordanov G. (2013). Advanced strategies for drug delivery in nanomedicine. In: Kralchevsky P, Miller R, Ravera F, eds. Colloid and interface chemistry for nanotechnology. Progress in Colloid and Interface Science. Boca Raton, USA: CRC Press, 3–36
   Google Scholar
• Yordanov G, Evangelatov A, Skrobanska R. (2013). Epirubicin loaded to pre-polymerized poly(butyl cyanoacrylate) nanoparticles: preparation and in vitro evaluation in human lung adenocarcinoma cells. Colloids Surf B Biointerfaces 107:115–23
   PubMed Web of Science ®Google Scholar
• Yordanov G, Skrobanska R, Evangelatov A. (2011). Entrapment of epirubicin in poly(butyl cyanoacrylate) colloidal nanospheres by nanoprecipitation: formulation development and in vitro studies on cancer cell lines. Colloids Surf B Biointerfaces 92:98–105
   PubMed Web of Science ®Google Scholar
• Zhou Q, Sun X, Zeng L, et al. (2009). A randomized multicenter phase II clinical trial of mitoxantrone-loaded nanoparticles in the treatment of 108 patients with unresected hepatocellular carcinoma. Nanomedicine 5:419–23
   PubMed Web of Science ®Google Scholar
• Zimmer A, Mutschler E, Lambrecht G, et al. (1994). Pharmacokinetic and pharmacodynamic aspects of an ophthalmic pilocarpine nanoparticle-delivery-system. Pharm Res 11:1435–42
   PubMed Web of Science ®Google Scholar