5,855
Views
86
CrossRef citations to date
0
Altmetric
Review Article

Molecular imprinted polymers as drug delivery vehicles

Pages 2262-2271 | Received 14 Aug 2014, Accepted 24 Sep 2014, Published online: 15 Oct 2014

References

  • Ahad A, Aqil M, Ali A. (2014). Investigation of antihypertensive activity of carbopol valsartan transdermal gel containing 1,8-cineole. Int J Biol Macromol 64:144–9
  • Alvarez-Lorenzo C, Concheiro A, (2013a). From drug dosage forms to intelligent drug delivery systems: a change of paradigm. In: Alvarez-Lorenzo C, Concheiro A, eds. Smart materials for drug delivery. Chap. 1. Vol. 1. Cambridge: RSC, 1–32
  • Alvarez-Lorenzo C, Concheiro A, eds. (2013b). Molecularly imprinted polymers as components of drug delivery systems. In: Alvarez-Lorenzo C, Concheiro A, eds. Handbook of molecularly imprinted polymers. Chap. 8. Shrewsbury, U.K., Smithers Rapra Publishing, 309–49
  • Alvarez-Lorenzo C, González-Chomón C, Concheiro A. (2013c). Molecularly imprinted hydrogels for affinity-controlled and stimuli-responsive drug delivery. In: Alvarez-Lorenzo C, Concheiro A, Schneider HJ, Shahinpoor M, eds. Smart materials for drug delivery. Chap. 21. Vol. 1. Cambridge: RSC, 228–60
  • Alvarez-Lorenzo C, Hiratani H, Gomez-Amoza JL, et al. (2002). Soft contact lenses capable of sustained delivery of timolol. J Pharm Sci 91:2182–92
  • Alvarez-Lorenzo C, Yanez F, Barreiro-Iglesias R, Concheiro A. (2006). Imprinted soft contact lenses as norfloxacin delivery systems. J Control Release 113:236–44
  • Alvarez-Lorenzo C, Yañez-Gomez F, Concheiro A. (2013d). Modular biomimetic drug delivery systems. In: Dumitriu S, Popa V, eds. Polymeric materials, medicinal and pharmaceutical applications. Chap. 4. Boca Raton, FL: CRC Press, 85–122
  • Anirudhan TS, Divya PL, Nima J. (2013). Silylated montmorillonite based molecularly imprinted polymer for the selective binding and controlled release of thiamine hydrochloride. React Funct Polym 73:1144–55
  • Aqil M. Zafar S, Ali A, Ahmad S. (2005). Transdermal drug delivery of labetolol hydrochloride: system development, in vitro; ex vivo and in vivo characterization. Curr Drug Deliv 2:125–131
  • Arshady R, Mosbach K. (1981). Synthesis of substrate-selective polymers by host-guest polymerization. Macromol Chem 182:687–92
  • Azodi-Deilami S, Abdouss M, Seyedi SR. (2010). Synthesis and characterization of molecularly imprinted polymer for controlled release of tramadol. Cent Eur J Chem 8:687–95
  • Bhaskarapillai A, Sevilimedu N, Sellergren B. (2009). Synthesis and characterization of imprinted polymers for radioactive waste reduction. Ind Eng Chem Res 48:3730–7
  • Bodhibukkana C, Srichana T, Kaewnopparat S, et al. (2006). Composite membrane of bacterially-derived cellulose and molecularly imprinted polymer for use as a transdermal enantioselective controlled-release system of racemic propranolol. J Control Release 113:43–56
  • Braga MEM, Yanez F, Alvarez-Lorenzo C, et al. (2010). Improved drug loading/release capacities of commercial contact lenses obtained by supercritical fluid assisted molecular imprinting methods. J Control Release 148:e102–4
  • Byrne ME, Park K, Peppas NA. (2002). Molecular imprinting within hydrogels. Adv Drug Deliv Rev 54:149–61
  • Cai W, Gupta RB. (2004). Molecularly-imprinted polymers selective for tetracycline binding. Sep Purif Technol 35:215–21
  • Caro E, Marce RM, Cormack PAG, et al. (2005). Synthesis and application of an oxytetracycline imprinted polymer for the solid-phase extraction of tetracycline antibiotics. Anal Chim Acta 552:81–6
  • Cirillo G, Curcio M, Parisi OI, et al. (2010b). Gastro-intestinal sustained release of phytic acid by molecularly imprinted microparticles. Pharm Dev Technol 15:526–31
  • Cirillo G, Iemma F, Puoci F, et al. (2009). Imprinted hydrophilic nanospheres as drug delivery systems for 5-fluorouracil sustained release. J Drug Targeting 17:72–7
  • Cirillo G, Parisi OI, Curcio M, et al. (2010a). Molecularly imprinted polymers as drug delivery systems for the sustained release of glycyrrhizic acid. J Pharm Pharmacol 62:577–82
  • Cunliffe D, Kirby A, Alexander C. (2005). Molecularly imprinted drug delivery systems. Adv Drug Deliv Rev 57:1836–53
  • Curcio M, Cirillo G, Parisi OI, et al. (2012). Quercetin-imprinted nanospheres as novel drug delivery devices. J Funct Biomater 3:269–82
  • De Souza R, Zahedi P, Allen CJ, Piquette-Miller M. (2010). Polymeric drug delivery systems for localized cancer chemotherapy. Drug Deliv 17:365–75
  • Delie F, Blanco-Prieto MJ. (2005). Polymeric particulates to improve oral bioavailability of peptide drugs. Molecules 10:65–80
  • Demetzos C, Pippa N. (2014). Advanced drug delivery nanosystems (aDDnSs): a mini-review. Drug Deliv 21:250–7
  • Fournier E, Passirani C, Colin N, et al. (2004). Development of novel 5-FU-loaded poly(methylidenemalonate 2.1.2)-based microspheres for the treatment of brain cancers. Eur J Pharm Biopharm 57:189–97
  • Gaspar R, Duncan R. (2009). Polymeric carriers: preclinical safety and the regulatory implications for design and development of polymer therapeutics. Adv Drug Deliv Rev 61:1220–31
  • Hillberg AL, Brain KR, Allender CJ. (2005). Molecular imprinted polymer sensors: implications for therapeutics. Adv Drug Deliv Rev 57:1875–89
  • Hiratani H, Alvarez-Lorenzo C. (2002). Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid. J Control Release 83:223–30
  • Hiratani H, Alvarez-Lorenzo C. (2004). The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems. Biomaterials 25:1105–13
  • Hiratani H, Fujiwara A, Tamiya Y, et al. (2005b). Ocular release of timolol from molecularly imprinted soft contact lenses. Biomaterials 26:1293–8
  • Hiratani H, Mizutani Y, Alvarez-Lorenzo C. (2005a). Controlling drug release from imprinted hydrogels by modifying the characteristics of the imprinted cavities. Macromol Biosci 5:728–33
  • Jang R, Kim KH, Zaidi SA, et al. (2011). Analysis of phospholipids using an open-tubular capillary column with a monolithic layer of molecularly imprinted polymer in capillary electrochromatography-electrospray ionization-tandem mass spectrometry. Electrophoresis 32:2167–73
  • Jantarat C, Tangthong N, Songkro S, et al. (2008). S-propranolol imprinted polymer nanoparticle-on-microsphere composite porous cellulose membrane for enantioselectively controlled delivery of racemic propranolol. Int J Pharm 349:212–25
  • Johnson KR, Young KK, Fan W. (1999). Antagonistic interplay between antimitotic and G1–S arresting agents observed in experimental combination therapy. Clin Cancer Res 5:2559–65
  • Kalmarkar RN, Kulkarni MG, Mashelkar RA. (1997). Pendent chain linked delivery systems: II. Facile hydrolysis through molecular imprinting effects. J Control Release 43:235–43
  • Kempe H, Pujolras AP, Kempe M. (2014). Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. Pharm Res. doi: 10.1007/s11095-014-1468-2
  • Kryscio DR, Peppas NA. (2009). Mimicking biological delivery through feedback-controlled drug release systems based on molecular imprinting. AIChE J 55:1311–24
  • Kumari A, Yadav SK, Yadav SC. (2010). Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B: Biointerfaces 75:1–18
  • Li S, Tiwari A, Ge Y, Fei D. (2010). A pH-responsive, low crosslinked, molecularly imprinted insulin delivery system. Adv Mat Lett 1:4–10
  • Liechty WB, Kryscio DR, Slaughter BV, Peppas NA. (2010). Polymers for drug delivery systems. Annu Rev Chem Biomol Eng 1:149–73
  • Lulinski P. (2013). Molecularly imprinted polymers as the future drug delivery devices. Acta Poloniae Pharm-Drug Res 70:601–9
  • Lulinski P, Maciejewska D. (2009). Examination of imprinting process with molsidomine as a template. Molecules 14:2212–25
  • Mohajeri SA, Malaekeh-Nikouei B, Sadegh H. (2012). Development of a pH-responsive imprinted polymer for diclofenac and study of its binding properties in organic and aqueous media. Drug Dev Ind Pharm 38:616–22
  • Mohajeri SA, Sajadi TSA, Hassanpour MM. (2014). Preparation of a pH-sensitive pantoprazole-imprinted polymer and evaluation of its drug-binding and releasing properties. Sci China Chem 57:857–65
  • Mora-Huertas CE, Fessi H, Elaissari A. (2010). Polymer-based nanocapsules for drug delivery. Int J Pharm 385:113–42
  • Norell MC, Andersson HS, Nicholls IA. (1998). Theophylline molecularly imprinted polymer dissociation kinetics: a novel sustained release drug dosage mechanism. J Mol Recognit 11:98–102
  • Okamoto Y, Kawashima M, Yamamoto K, Hatada K. (1984). Useful chiral packing materials for high-performance liquid chromatographic resolution. Cellulose triacetate and tribenzoate coated on macroporous silica gel. Chem Lett 106:739–42
  • Parisi OI, Morelli C, Puoci F, et al. (2014). Magnetic molecularly imprinted polymers (MMIPs) for carbazole derivatives release in targeted cancer therapy. J Mater Chem B 2:6619–625
  • Puoci F, Cirillo G, Curcio M, et al. (2008b). Molecularly imprinted polymers for α-tocopherol delivery. Drug Deliv 15:253–8
  • Puoci F, Iemma F, Cirillo G, et al. (2007). Molecularly imprinted polymers for 5-fluorouracil release in biological fluids. Molecules 12:805–14
  • Puoci F, Iemma F, Muzzalupo R, et al. (2004). Spherical molecularly imprinted polymers (SMIPs) via a novel precipitation polymerization in the controlled delivery of sulfasalazine. Macromol Biosci 4:22–6
  • Puoci F, Iemma F, Picci N. (2008a). Stimuli-responsive molecularly imprinted polymers for drug delivery: a review. Current Drug Deliv 5:85–96
  • Rangasamy M, Parthiban KG. (2010). Recent advances in novel drug delivery systems. Int J Res Ayurveda Pharm 1:316–26
  • Sancho R, Minguillon C. (2009). The chromatographic separation of enantiomers through nanoscale design. Chem Soc Rev 38:797–805
  • Sellergren B, Allender CJ. (2005). Molecularly imprinted polymers: a bridge to advanced drug delivery. Adv Drug Deliv Rev 57:1733–41
  • Singh B, Chauhan N. (2008). Preliminary evaluation of molecular imprinting of 5-fluorouracil within hydrogels for use as drug delivery systems. Acta Biomater 4:1244–54
  • Sood N, Bhardwaj A, Mehta S, Mehta A. (2014). Stimuli-responsive hydrogels in drug delivery and tissue engineering. Drug Deliv 21:1–23
  • Srichana T, Suedee R. (2001). Evaluation of stereoselective dissolution of racemic salbutamol matrices prepared with commonly used excipients and 1H NMR study. Drug Dev Ind Pharm 27:457–64
  • Subat M, Borovik AS, Konig BJ. (2004). Synthetic creatinine receptor: imprinting of a Lewis acidic zinc(II)cyclen binding site to shape its molecular recognition selectivity. J Am Chem Soc 126:3185–90
  • Suedee R. (2013a). Novel strategic innovations for designing drug delivery system using molecularly imprinted micro/nanobeads. Int J Pharm Sci Rev Res 20:235–68
  • Suedee R. (2013b). The use of molecularly imprinted polymers for dermal drug delivery. Pharm Anal Acta 4:1–23
  • Suedee R, Bodhibukkana C, Tangthong N, et al. (2008). Development of a reservoir-type transdermal enantioselective-controlled delivery system for racemic propranolol using a molecularly imprinted polymer composite membrane. J Control Release 129:170–8
  • Suedee R, Heard CM. (1997). Direct resolution of propranolol and bupranolol by thin layer chromatography using cellulose derivatives as stationary phase. Chirality 9:139–44
  • Suedee R, Jantarat C, Lindner W, et al. (2010). Development of a pH-responsive drug delivery system for enantioselective-controlled delivery of racemic drugs. J Control Release 142:122–31
  • Suedee R, Srichana T, Chotivatesin R, Martin GP. (2003). Stereoselective release behaviors of imprinted bead matrices. Drug Dev Ind Pharm 28:545–54
  • Suedee R, Srichana T, Martin GP. (2000). Evaluation of matrices containing molecularly imprinted polymers in the enantioselective controlled delivery of b-blockers. J Control Release 66:135–47
  • Suedee R, Srichana T, Rattananont T. (2002). Enantioselective release of controlled delivery granules based on molecularly imprinted polymers. Drug Deliv 9:19–30
  • Sumi VS, Kala R, Praveen RS, Rao TP. (2008). Imprinted polymers as drug delivery vehicles for metal-based anti-inflammatory drug. Int J Pharm 349:30–7
  • Sutradhar KB, Sumi CD. (2014). Implantable microchip: the futuristic controlled drug delivery system. Drug Deliv. doi: 10.3109/10717544.2014.903579
  • Tiwari G, Tiwari R, Sriwastawa B, et al. (2012). Drug delivery systems: an updated review. Int J Pharm Investig 2:2–11
  • Veiseh O, Gunn JW, Zhang M. (2010). Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. Adv Drug Deliv Rev 62:284–304
  • Venkatesh S, Saha J, Pass S, Byrne ME. (2008). Transport and structural analysis of molecular imprinted hydrogels for controlled drug delivery. Eur J Pharm Biopharm 69:852–60
  • Venkatesh S, Sizemore SP, Byrne ME. (2007). Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics. Biomaterials 28:717–24
  • Vilar G, Tulla-Puche J, Albericio F. (2012). Polymers and drug delivery systems. Curr Drug Deliv 9:367–94
  • Wang NX, Von Recum HA. (2011). Affinity-based drug delivery. Macromol Biosci 11:321–32
  • Wulff G, Sarhan A. (1972). Über die Anwendung von enzymanalog gebauten polymeren zur racemattrennung. Angew Chem 84:364
  • Yanez F, Martikainen L, Braga MEM, et al. (2011). Supercritical fluid-assisted preparation of imprinted contact lenses for drug delivery. Acta Biomater 7:1019–30
  • Zaidi SA. (2013a). Dual-templates molecularly imprinted monolithic columns for the evaluation of serotonin and histamine in CEC. Electrophoresis 34:1375–82
  • Zaidi SA. (2013b). Recent advancement in various electrochemical and immunosensing strategies for detection of chloramphenicol. Int J Electrochem Sci 8:9936–55
  • Zaidi SA, Cheong WJ. (2008). Robust open tubular layer of S-ketoprofen imprinted polymer for chiral LC separation. J Sep Sci 31:2962–70
  • Zaidi SA, Cheong WJ. (2009). Preparation of an open-tubular capillary column with a monolithic layer of S-ketoprofen imprinted and 4-styrenesulfonic acid incorporated polymer and its enhanced chiral separation performance in capillary electrochromatography. J Chromatogr A 1216:2947–52
  • Zaidi SA, Han KM, Kim SS, et al. (2009). Open tubular layer of S-ofloxacin imprinted polymer fabricated in silica capillary for chiral CEC separation. J Sep Sci 32:996–1001
  • Zaidi SA, Lee SM, Cheong WJ. (2011). Open tubular capillary columns with basic templates made by the generalized preparation protocol in capillary electrochromatography chiral separation and template structural effects on chiral separation capability. J Chromatogr A 1218:1291–9
  • Zaidi SA, Shin JH. (2014). Molecularly imprinted polymer electrochemical sensors based on synergistic effect of composites synthesized from graphene and other nanosystems. Int J Electrochem Sci 9:4598–616
  • Zhao K, Singh J. (1999). In vitro percutaneous absorption enhancement of propranolol hydrochloride through porcine epidermis by terpenes/ethanol. J Control Release 62:359–66

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.