1,036
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Synthesis of a novel polyamidoamine dendrimer conjugating with alkali blue as a lymphatic tracer and study on the lymphatic targeting in vivo

, , , , , & show all
Pages 2298-2308 | Received 05 Oct 2014, Accepted 18 Oct 2014, Published online: 19 Nov 2014

References

  • Alex JC, Weaver DL, Fairbank JT, et al. (1993). Gamma-probe-guided lymph node localization in malignant melanoma. Surg Oncol 2:303–8
  • Barrett T, Choyke PL, Kobayashi H. (2006). Imaging of the lymphatic system: new horizons. Contrast Media Mol I 1:230–45
  • Buhleier E, Wehner W, Vogtle F. (1978). Cascade- and nonskid-chain-like syntheses of molecular cavity topologies. Synthesis 2:155–8
  • Chen H, Banaszak Holl M, Orr BG, et al. (2003). Interaction of dendrimers (artificial proteins) with biological hydroxyapatite crystals. J Dent Res 82:443–8
  • Choi SH, Moon WK, Hong JH, et al. (2007). Lymph node metastasis: ultra small superparamagnetic iron oxide enhanced MR imaging versus PET/CT in a rabbit model. Radiology 242:137–43
  • Clement O, Luciani A. (2004). Imaging the lymphatic system: possibilities and clinical applications. Eur Radiol 14:1498–507
  • Dowlatshahi K, Fan M, Snider HC, Habib FA. (1997). Lymph node micrometastases from breast carcinoma: reviewing the dilemma. Cancer 80:1188–97
  • Fisher B, Bauer M, Wickerham DL, et al. (1983). Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. Cancer 52:1551–7
  • Giuliano AE, Kirgan DM, Guenther JM. (1994). Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg 220:391–8
  • Ke W, Shao K, Huang R, et al. (2009). Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. Biomaterials 30:6976–85
  • Khalil HH, Elaffandi AH, Afifi A, et al. (2008). Sentinel Lymph Node Biopsy (SLNB) in management of N0 stage T1–T2 lip cancer as a “Same Day” procedure. Oral Oncol 44:608–12
  • Kobayashi H, Kawamoto S, Bernardo M, et al. (2006). Delivery of gadolinium-labeled nanoparticles to the sentinel lymph node: comparison of the sentinel node visualization and estimations of intranodal gadolinium concentration by the magnetic resonance imaging. J Control Release 111:343–51
  • Kobayashi H, Kawamoto S, Sakai Y, et al. (2004). Lymphatic drainage imaging of breast cancer in mice by micro-magnetic resonance lymphangiography using a nanosize paramagnetic contrast agent. J Natl Cancer Inst 96:703–8
  • Kobayashi H, Koyama Y, Barrett T, et al. (2007). Multimodal nanoprobes for radionuclide and fivecolor near-infrared optical lymphatic imaging. ACS Nano 1:258–64
  • Kobayashi H, Sato N, Hiraga A, et al. (2001). 3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with reference to their pharmacokinetic properties. Magn Reson Med 45:454–60
  • Koller M, Barsuk D, Zipple D, et al. (1998). Sentinel lymph node involvement – a predictor for axillary node status with breast cancer – Has the time come? Eur J Surg Oncol 24:166–8
  • Kurtoglu YE, Mishra MK, Kannan S, Kannan RM. (2010). Drug release characteristics of PAMAM dendrimer–drug conjugates with different linkers. Int J Pharmaceut 384:189–94
  • Lei XG, Jockusch S, Turro NJ, et al. (2008). EPR characterization of gadolinium (III)-containing-PAMAM-dendrimers in the absence and in the presence of paramagnetic probes. J Colloid Interface Sci 322:457–64
  • Lim J, Chouai A, Lo ST, et al. (2009). Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages. Bioconjug Chem 20:2154–61
  • Liu Q, Zuo WS, Wang YS, et al. (2000). The study of sentinel lymph nodes biopsy in breast cancer. J Qilu Oncol 7:217–53
  • Lohrmann C, Foeldi E, Langer M. (2009). MR imaging of the lymphatic system in patients with lipedema and lipo-lymphedema. Microvasc Res 77:335–9
  • Luciani A, Itti E, Rahmouni A, et al. (2006). Lymph node imaging: basic principles. Eur J Radiol 58:338–44
  • Menjoge AR, Kannan RM, Tomalia DA. (2010). Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications. Drug Discov Today 15:171–85
  • Misselwitz B. (2006). MR contrast agents in lymph node imaging. Eur J Radiol 58:375–82
  • Morton DL, Wen DR, Wong JH, et al. (1992). Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 127:392–9
  • Mounzer R, Shakarin P, Papademetris X, et al. (2007). Dynamic imaging of lymphatic vessels and lymph nodes using a bimodal nanoparticulate contrast agent. Lymphat Res Biol 5:151–8
  • Noguchi M, Tsugawa K, Bando E. (1999). Sentinel lymphadenectomy in breast cancer: identification of sentinel lymph node and detection of metastases. Breast Cancer Res Tr 53:97–104
  • Patel DA, Henry JE, Good TA. (2007). Attenuation of beta-amyloid-induced toxicity by sialic-acid-conjugated dendrimers: role of sialic acid attachment. Brain Res 1161:95–105
  • Ratnesh J, Dandekara P, Patravale V. (2009). Diagnostic nanocarriers for sentinel lymph node imaging. J Control Release 138:90–102
  • Reitsamer R, Peintinger F, Prokop E, et al. (2003). Sentinel lymph node biopsy alone without axillary lymph node dissection – follow up of sentinel lymph node negative breast cancer patients. Eur J Surg Oncol 29:221–3
  • Satish KN, Padmaja G, Majeti BK, et al. (2011). Advances in lymphatic imaging and drug delivery. Adv Drug Deliv Rev 63:876–85
  • Tam JP, Spetzler JC. (2001). Synthesis and application of peptide dendrimers as protein mimetics. Curr Protoc Protein Sci 18:15
  • Tomalia DA, Baker H, Dewald JR, et al. (1985). A new class of polymers: starburst-dendritic macromolecules. Polym J 17:117–32
  • Tomalia DA, Reyna LA, Svenson S. (2007). Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem Soc Trans 3:61–7
  • Wang SJ, Yang R, Yao HM, et al. (2009). In vivo lymphatic targeting of methylene blue with microemulsion and multiple microemulsion. Drug Deliv 16:371–7
  • Yang H, Lopina ST. (2007). Stealth dendrimers for antiarrhythmic quinidine delivery. J Mater Sci-Mater M 18:2061–5
  • Ye TT, Zhang WJ, Sun MS, et al. (2014). Study on intralymphatic-targeted hyaluronic acid-modified nanoliposome: influence of formulation factors on the lymphatic targeting. Int J Pharmaceut 471:245–57

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.