References
- Ardizzone S, Maconi G, Russo A, et al. (2006). Randomized controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 55:47–53
- Chao GT, Deng HX, Huang Q, et al. (2006). Preparation and characterization of pH sensitive semi-interpenetrating network hydrogel based on methacrylic acid, bovine serum albumin (BSA), and PEG. J Polym Res 13:349–55
- Collnot EM, Ali H, Lehr CM. (2012). Nano-and microparticulate drug carriers for targeting of the inflamed intestinal mucosa. J Control Release 161:235–46
- Cruise GM, Scharp DS, Hubbell JA. (1998). Characterization of permeability and network structure of interfacially photopolymerized poly (ethylene glycol) diacrylate hydrogels. Biomaterials 19:1287–94
- Feng SS, Mei L, Anitha P, et al. (2009). Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel. Biomaterials 30:3297–306
- Gann MJM, Higginbotham CL, Geever LM, Nugent MJD. (2009). The synthesis of novel pH-sensitive poly(vinyl alcohol) composite hydrogels using a freeze/thaw process for biomedical applications. Int J Pharm 372:154–61
- Ha JC, Kim SY, Lee YM. (1999). Poly(ethylene oxide)-poly(propylene oxide) – poly(ethylene oxide) (pluronic)/poly(e-caprolactone) (PCL) amphiphilic block copolymeric nanospheres. I. Preparation and characterization. J Control Release 62:381–92
- Hamidi M, Azadi A, Rafiei P. (2008). Hydrogel nanoparticles in drug delivery. Adv Drug Deliver Rev 60:1638–49
- Harris MS, Lichtenstein GR. (2011). Review article: delivery and efficacy of topical 5-aminosalicylic acid (mesalazine) therapy in the treatment of ulcerative colitis. Aliment Pharm Therap 33:996–1009
- He CB, Cui FY, Yin LC, et al. (2009). A polymeric composite carrier for oral delivery of peptide drugs: bilaminated hydrogel film loaded with nanoparticles. Eur Polym J 45:368–76
- Horkay F, Han MH, Han IS, et al. (2006). Separation of the effects of pH and polymer concentration on the swelling pressure and elastic modulus of a pH-responsive hydrogel. Polymer 47:7335–8
- Huttunen KM, Tani N, Juvonen R, et al. (2013). Design, synthesis, and evaluation of novel cyclic phosphates of 5-aminosalicylic acid as cytochrome P450-activated prodrug. Mol Pharm 10:532–7
- Jia WJ, Liu JG, Zhang YD, Wang JW. (2007). Preparation, characterization, and optimization of pancreas-targeted 5-Fu loaded magnetic bovine serum albumin microspheres. J Drug Target 15:140–5
- Klotz U. (2012). The pharmacological profile and clinical use of mesalazine (5-aminosalicylic acid). Arzneimittelforschung 62:53–8
- Li YM, Wang YN, Liu Y, et al. (2014). The possible role of the novel cytokines IL-35 and IL-37 in inflammatory bowel disease. Mediators Inflamm DOI: org/10.1155/2014/136329
- Martin TD, Chan SSM, Hart AR. (2014). Environmental factors in the relapse and recurrence of inflammatory bowel disease: a review of the literature. Dig Dis Sci. DOI: 10.1007/S 10620-014-3437-3
- Mura C, Nàcher A, Merino V, et al. (2011). N-succinyl chitosan systems for 5-aminosalicylic acid colon delivery: in vivo study with TNBS-induced colitis model. Int J Pharm 416:145–54
- Qiu Y, Park K. (2001). Environment-sensitive hydrogels for drug delivery. Adv Drug Deliv Rev 53:321–39
- Römkens TEH, Kampschreur MT, Drenth JPH, et al. (2012). High mucosal healing rates in 5-ASA-treated ulcerative colitis patients: results of a meta-analysis of clinical trials. Inflamm Bowel Dis 18:2190–8
- Shaikh M, Kichenadasse G, Choudhury NR, et al. (2013). Non-vascular drug elutin stents as localized controlled drug delivery platform: preclinical and clinical experience. J Control Release 172:105–17
- Shim WS, Kim JH, Park H, et al. (2006). Biodegradability and biocompatibility of a pH- and thermo-sensitive hydrogel formed from a sulfonamide-modified poly(ε-caprolactone-co-lactide)-poly(ethylene glycol)-poly(ε-caprolactone-co-lactide) block copolymer. Biomaterials 27:5178–85
- Sonu I, Wong R, Rothenberg ME. (2013). 5-ASA induced recurrent myopericarditis and cardiac tamponade in a patient with ulcerative colitis. Dig Dis Sci 58:2148–50
- Thomas S, Baumgart DC. (2012). Targeting leukocyte migration and adhesion in Crohn’s disease and ulcerative colitis. Inflammopharmacology 20:1–18
- Trivedi PP, Jena GB. (2012). Dextran sulfate sodium-induced ulcerative colitis leads to increased hematopoiesis and induces both local as well as systemic genotoxicity in mice. Mutat Res-Gen Tox En 744:172–83
- Trivedi PP, Jena GB. (2013). Melatonin reduces ulcerative colitis-associated local and systemic damage in mice: investigation on possible mechanisms. Dig Dis Sci 58:3460–74
- Wang K, Fu SZ, Gu YC, et al. (2009). Synthesis and characterization of biodegradable pH-sensitive hydrogel based on poly(ε-caprolactone), methacrylic acid, and poly(ethylene glycol). Polym Degrad Stabil 94:730–7
- Wang K, Xu X, Wang YJ, et al. (2010). Synthesis and characterization of poly(methoxyl ethylene glycol-caprolactone-co-methacrylic acid-co-poly(ethylene glycol) methyl ether methacrylate) pH-sensitive hydrogel for delivery of dexamethasone. Int J Pharm 389:130–8
- Wang YJ, Wang C, Wang YJ, et al. (2012). Micelles of methoxy poly(ethylene glycol)-poly(ε-caprolactone) as a novel drug delivery vehicle for tacrolimus. J Biomed Nanotechnol 9:1–11
- Wei L, Wang JL, Zou LZ, Zhu SQ. (2008). Synthesis and characteristic of the thermo- and pH-sensitive hydrogel and microporous hydrogel induced by the NP-10 aqueous two-phase system. Eur Polym J 44:3688–99
- Wolk O, Epstein S, Dahan VL, et al. (2013). New targeting strategies in drug therapy of inflammatory bowel disease: mechanistic approaches and opportunities. Expert Opin Drug Del 10:1275–86
- Xu FJ, Kang ET, Neoh KG. (2006). pH- and temperature-responsive hydrogels from crosslinked triblock copolymers prepared via consecutive atom transfer radical polymerizations. Biomaterials 27:2787–97
- Yin LC, Ding JY, He CB, et al. (2009). Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanopariticles in oral insulin delivery. Biomaterials 30:5691–700