Advanced search
Publication Cover
Drug Delivery Volume 23, 2016 - Issue 8
Submit an article Journal homepage
1,277
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Intraocular distribution of topically applied hydrophilic and lipophilic substances in rat eyes

Nurul Alimah Abdul NasirFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Malaysia, ;Brain & Neuroscience, Communities of Research (Core), Research Management Institute (RMI), Universiti Teknologi MARA, Shah Alam, Malaysia, Correspondence[email protected]
,
Puneet AgarwalDepartment of Ophthalmology, International Medical University, IMU Clinical School, Jalan Rasah, Seremban, Malaysia,
,
Renu AgarwalFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Malaysia, ;Brain & Neuroscience, Communities of Research (Core), Research Management Institute (RMI), Universiti Teknologi MARA, Shah Alam, Malaysia,
,
Igor IezhitsaFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Malaysia, ;Brain & Neuroscience, Communities of Research (Core), Research Management Institute (RMI), Universiti Teknologi MARA, Shah Alam, Malaysia, ;Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia,
,
Renad AlyautdinFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Malaysia, ;Brain & Neuroscience, Communities of Research (Core), Research Management Institute (RMI), Universiti Teknologi MARA, Shah Alam, Malaysia, ;Scientific Centre for Expertise of Medical Application Products, Ministry of Health, Moscow, Russia,
,
Natalia N. NukolovaLaboratory of Chemical Design of Bionanomaterials, Chemistry Department, M.V. Lomonosov Moscow State University, Moscow, Russia, and ;Department of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia
,
Vladimir P. ChekhoninDepartment of Fundamental and Applied Neurobiology, Serbsky National Research Center for Social and Forensic Psychiatry, Moscow, Russia
&
Nafeeza Mohd IsmailFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Malaysia, ;Brain & Neuroscience, Communities of Research (Core), Research Management Institute (RMI), Universiti Teknologi MARA, Shah Alam, Malaysia,
show all
Pages 2765-2771 | Received 27 May 2015, Accepted 24 Jul 2015, Published online: 14 Aug 2015

References

  • Acheampong AA, Shackleton M, John B, et al. (2002). Distribution of brimonidine into anterior and posterior tissues of monkey, rabbit, and rat eyes. Drug Metab Dispos 30:421–9
  • Ahmed I, Patton TF. (1985). Importance of the noncorneal absorption route in topical ophthalmic drug delivery. Invest Ophthalmol Vis Sci 26:584–7
  • Ahmed I, Patton TF. (1987). Disposition of timolol and inulin in the rabbit eye following corneal versus non-corneal absorption. Int J Pharm 38:9–21
  • Agarwal R, Iezhitsa I, Agarwal P, et al. (2014). Liposomes in topical ophthalmic drug delivery: an update. Drug Deliv. [Epub ahead of print]. doi:10.3109/10717544.2014.943336
  • Alyautdin RN, Iezhitsa IN, Agarwal R. (2014). Transcorneal drug delivery: prospects for the use of liposomes. Vestn Oftalmol 130:117–22
  • Chien DS, Homsy JJ, Gluchowski C, Tang-Liu DDS. (1990). Corneal and conjunctival/scleral penetration of p-aminoclonidine, AGN 190342, and clonidine in rabbit eyes. Curr Eye Res 9:1051–9
  • Davis JL, Gilger BC, Robinson MR. (2004). Novel approaches to ocular drug delivery. Curr Opin Mol Ther 6:195–205
  • Fitzgerald P, Hadgraft J, Wilson CG. (1987). A gamma scintigraphic evaluation of the precorneal residence of liposomal formulations in the rabbit. J Pharm Pharmacol 39:487–90
  • Gaudana R, Ananthula HK, Parenky A, Mitra AK. (2010). Ocular drug delivery. AAPS J 12:348–60
  • Järvinen K, Järvinen T, Urtti A. (1995). Ocular absorption following topical delivery. Adv Drug Deliv Rev 16:3–19
  • Keuter J, Ramge P, Petrov V, et al. (2003). Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drugs to the nanoparticles. Pharm Res 20:409–16
  • Maurice DM, Mishima S. (1984). Ocular pharmacokinetics. In: Sears ML, ed. Pharmacology of the eye. Vol. 69. Berlin: Springer, 19–116
  • Nii T, Ishii F. (2005). Encapsulation efficiency of water-soluble and insoluble drugs in liposomes prepared by the microencapsulation vesicle method. Int J Pharm 298:198–205
  • Prausnitz MR, Noonan JS. (1998). Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye. J Pharm Sci 87:1479–88
  • Raviola G. (1983). Conjunctival and episcleral blood vessels are permeable to blood-borne horseradish peroxidase. Invest Ophthalmol Vis Sci 24:725–36
  • Sasaki H, Matsukawa Y, Hashida M, Sezaki H. (1987). Characterization of alkylcarbamoyl derivatives of 5-fluorouracil and their application to liposome. Int J Pharm 36:147–56
  • Schaeffer HE, Krohn DL. (1982). Liposomes in topical drug delivery. Invest Ophthalmol Vis Sci 22:220–7
  • Steuhl P, Rohen JW. (1983). Absorption of horse-radish peroxidase by the conjunctival epithelium of monkeys and rabbits. Graefes Arch Clin Exp Ophthalmol 220:13–18
  • Thombre AG, Himmelstein KJ. (1984). Quantitative evaluation of topically applied pilocarpine in the precorneal area. J Pharm Sci 73:219–22
  • Urtti A, Salminen L, Miinalainen O. (1985). Systemic absorption of ocular pilocarpine is modified by polymer matrices. Int J Pharm 23:147–61
  • Wilson CG. (2004). Topical drug delivery in the eye. Exp Eye Res 78:737–43

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.